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16 - 22 octobre 2012

Actualits francophones : Une confrence-dbat sur lautisme Les nouvelles structures pour autistes dans le Mlantois Le spectacle du combat quotidien d'un papa, par la drision et le coup de gueule Organisation d'une confrence-dbat sur la gntique et l'autisme Maison d'accueil spcialise : le chantier avance grands pas L'autisme, ils en ont parl ensemble Enfants autistes : Je ne trouve pas que je suis diffrente Un forum pour aborder lautisme autrement La gntique au cur de la confrence-dbat Autisme : la vie autrement Veauche : La France accuse, dans le domaine de la prise en charge, un srieux retard Le bonhomme de l'ombre, roman sur l'autisme de Maurice Coudy

Actualits scientifiques internationales : Modeling of Autism Genetic Variations in Mice: Focusing on Synaptic and Microcircuit GABA system dysfunction in autism and related disorders: From synapse to symptoms. Functional connectivity magnetic resonance imaging classification of autism. Brain Targeted treatments in autism and fragile X syndrome. Research in Autism Spectrum Corpus callosum abnormalities, intellectual disability, speech impairment, and autism in Extracting multiscale pattern information of FMRI based functional brain connectivity with Trends and topics in Early Intensive Behavioral Interventions for toddlers with autism.

Dysfunctions. Developmental Neuroscience Neuroscience and Biobehavioral Reviews

Disorders patients with haploinsufficiency of ARID1B. Clinical Genetics application on classification of autism spectrum disorders. Plos One Research in Autism Spectrum Disorders
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Abstractness and continuity in the syntactic development of young children with autism. Metaphor and metonymy in ASD children: A critical review from a developmental Methods for assessing sleep in children with autism spectrum disorders: A review. Research Diagnostic History and Treatment of School-aged Children with Autism Spectrum Disorder Assessment of anxiety in children and adolescents with autism spectrum disorders. Research Teaching caregivers to implement video modeling imitation training via iPad for their Collateral effects of mand training for children with autism. Research in Autism Spectrum Ensuring successful admission to hospital for young people with learning difficulties, autism

Autism Research perspective. Research in Autism Spectrum Disorders in Autism Spectrum Disorders and Special Health Care Needs. Nchs Data Brief in Autism Spectrum Disorders children with autism. Research in Autism Spectrum Disorders Disorders and challenging behaviour: a continuous quality improvement and change management programme. Child Evidence-based practice: Quality indicator analysis of antecedent exercise in autism Visual Scanning Patterns during the Dimensional Change Card Sorting Task in Children Teaching advanced operation of an iPod-based speech-generating device to two students Enhanced cortisol response to stress in children in autism. Journal of Autism and Evaluation of a self-instructional package on discrete-trials teaching to parents of children The effect of perceptual-motor training on attention in the children with autism spectrum spectrum disorders. Research in Autism Spectrum Disorders with Autism Spectrum Disorder. Autism Research and Treatment with autism spectrum disorders. Research in Autism Spectrum Disorders Developmental Disorders with autism. Research in Autism Spectrum Disorders disorders. Research in Autism Spectrum Disorders

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INDRE_ET_LOIRE Une confrence-dbat sur lautisme Brigitte BARNEOUD 342 mots 24 octobre 2012 La Nouvelle Rpublique du Centre Ouest NOUREP 37T 8 Franais Copyright 2012. La Nouvelle Rpublique du Centre Ouest. All Rights Reserved. Lautisme, daujourdhui demain: 40 ans de recherches par lcole de Tours. Cest ce thme que le conseil gnral dIndre-et-Loire a choisi pour ouvrir un nouveau cycle de confrences, consacr aux sujets de socit. LIndre-et-Loire compte de nombreux tablissements spcialiss, mais tous ne sont pas adapts laccueil de personnes atteintes dautisme et il ny a pas assez de places. Aujourdhui, alors quon value 440.000 le nombre de personnes qui souffrent de cette maladie en France, le constat demeure proccupant: lautisme reste une maladie diagnostique souvent trop tardivement, ce qui nuit sa prise en charge et accentue le handicap. Mme lorsque le diagnostic est pos, laccompagnement reste inadapt (non-scolarisation, isolement, etc.) Grce aux donnes de la recherche, on sait maintenant que cette pathologie est lie un trouble du fonctionnement crbral. Les travaux mens par lquipe de recherche Inserm de Tours ont t pionniers dans lavance de ces connaissances. Ils se fondent sur la collaboration troite entre les mdecins cliniciens et les chercheurs. Un panorama des donnes les plus rcentes, notamment celles portant sur linfluence des mutations gntiques perturbant la communication entre les neurones, sera prsent et mis en lien avec les perspectives thrapeutiques actuelles et futures. Trois gnrations dexperts de lcole de Tours, seront prsents:
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> Le professeur Frdrique Bonnet-Brilhault, chef du service pdopsychiatrie au CHU de Tours, coordonnateur du centre de ressources autisme de la rgion centre et responsable de lquipe Inserm Autisme U 930; > Le professeur Catherine Barthlmy, chef de service honoraire du centre de pdopsychiatrie, viceprsident de la commission neurosciences de lInserm; > Le professeur Gilbert Lelord, fondateur du centre universitaire de pdopsychiatrie et cofondateur de lunit Inserm U 930. Lautisme, daujourdhui demain , jeudi 25 octobre, 18h30, Htel du Dpartement, place de la Prfecture Tours. Gratuit, ouvert tous. Document NOUREP0020121024e8ao000a5

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Les nouvelles structures pour autistes dans le Mlantois 370 mots 24 octobre 2012 La Voix du Nord Copyright 2012 La Voix du Nord, tous droits rservs. Si vous navez pas daccord direct avec La Voix du Nord ou avec Factiva, vous avez uniquement la possibilit de consulter le prsent document, vous ne pouvez en aucun cas le rutiliser. 2012. C'est l'anne de l'autisme en France. Ce handicap d'origine gntique touche une fille pour quatre garons. On estime donc 400 000 le nombre d'individus atteints, en France, par cette maladie, ou de troubles envahissant le dveloppement. Et dans le Nord, cinquante-et-une d'entre eux sont concernes par l'amendement Creton. C'est--dire des personnes de plus de 20 ans, maintenues en instituts mdicaux ducatifs (IME), faute de place dans des centres pour adultes. Dans le Mlantois, Annoeullin, un IME pour adolescents autistes ouvrira l'an prochain. En 2014, un centre d'accueil pour adultes accueillera trente-deux personnes Attiches. La Fontinelle. C'est le premier IME pour adolescents dans la rgion, Annoeullin. Trente-six jeunes, de 12 20 ans, y seront accueillis partir de l'an prochain avec cet objectif, pour l'association Sesame autisme Nord : qu'ils deviennent le plus autonomes possible. L'Ore de la fort. Situ rue de la Faisanderie, Attiches, ce projet est port par l'association Autisme Nord qui gre dj quatre foyers d'accueil mdicaliss, Orchies et Templeuve et une maison de loisirs Seclin. L'Ore de la fort accueillera trente-deux autistes adultes rpartis dans quatre maisons de huit places, dont une d'accueil temporaire. Son ouverture est prvue pour 2014. La liste d'attente affiche 160 personnes. Il y aura une commission d'attribution qui choisira les jeunes, prioritairement du Nord et en fonction de leur handicap puisqu'on doit trouver un quilibre entre les degrs d'autisme , prcisait Gille Pourbaix en juin, dans nos colonnes. Les associations : Autisme Nord Tl :03 20 05 52 70 ; www.autisme -nord.org ; asso@autisme-nord.org. Sesame Autisme NPDC : Tl :03 21 45 47 45 ; www.sesame-autisme -5962.org ; sesameautisme@sesame-autisme -59-62.org. EPAJ 59 : Cre en 2011 pour Jason et Aurlien, elle concerne dix-huit familles dans le Nord - Pas-de-Calais, la Somme et les Ardennes. Elle participe notamment la promotion d'Handichien, pour remettre gratuitement des chiens d'assistance aux personnes porteuses de handicap. http://epaj59.fr/

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Le spectacle du combat quotidien d'un papa, par la drision et le coup de gueule 577 mots 24 octobre 2012 La Voix du Nord VOINOR Seclin Franais Copyright 2012 La Voix du Nord, tous droits rservs. Si vous navez pas daccord direct avec La Voix du Nord ou avec Factiva, vous avez uniquement la possibilit de consulter le prsent document, vous ne pouvez en aucun cas le rutiliser. Gabin au square, au salon de coiffure, l'cole... Dans Le Bal des pompiers , Laurent Savard raconte la vie de son fils, autiste. Un spectacle humoristique sur la diffrence, caustique mais qui respecte l'autre . Plus de dix mille personnes l'ont vu en un an. Demain soir, pour sa premire reprsentation dans le Nord, il sera la salle des ftes de Seclin, 20 h 30. PAR ANNE-SOPHIE PUJOL seclin@lavoixdunord.fr Gabin, votre fils, a dix ans, il est autiste et c'est le personnage principal de votre spectacle. Comment est venue l'criture ? J'ai commenc crire dans ma tte, au fur et mesure que je suivais Gabin. Le dclic, c'est surtout quand j'ai eu face moi cette directrice d'cole publique qui m'a dit en runion pdagogique : "Vous savez monsieur Savard, quand j'ai commenc ce mtier ce n'est certainement pas pour m'occuper d'enfants handicaps." Est-ce que c'est un spectacle sur l'autisme ou sur le handicap ? Je ne voulais pas faire rire du handicap mais autour du handicap et des gens qui se pensent normaux mais ne le sont pas. On a tous une diffrence plus ou moins marque. En France, on a mal la diffrence : l'autisme est un problme de diffrence. Un des moments symptomatique du spectacle c'est quand mon fils se met poil dans le square et que quelqu'un le voit. Du coup, je "pte les plombs" et moi aussi je me mets poil. Comme si les gens n'avaient jamais vu quelqu'un de nu ! En fait, devant moi, se droulait une succession de sketches, c'est aussi cette prise de conscience qui m'a fait crire. Et les gens rient, apprcient ? Oui, c'est un spectacle caustique mais qui respecte l'autre. Je ne voulais pas me "planter", donc j'ai attendu d'tre sr de ma lgitimit avant de monter seul en scne. Je crois que les mentalits ont aussi commenc changer avec le livre de Jean-Louis Fournier, O on va, Papa ? C'est aussi un spectacle politique, parce que vous voulez faire bouger les choses, interpeller ? L'autisme,
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c'est un problme de prise en charge : il n'y a pas assez de centres pour les enfants, on n'applique pas les nouvelles mthodes, on n'est pas assez bien form pour prendre en charge de faon prcoce les enfants. Ce spectacle, c'est celui du combat quotidien d'un papa, par l'humour, la drision, et le coup de gueule. tre parent d'un enfant autiste en 2012, c'est quoi ? C'est une vie o on joue d'autant plus son rle de parent. C'est avoir recours des personnes formes parce que vous ne pouvez pas tre "non stop" avec votre enfant. C'est tre patient : il s'est pass quatre ans pour qu'on ait un diagnostique pos qui s'est affin il y a trois mois et explique son hyperactivit. tre parent d'un enfant autiste, c'est, dans notre cas, l'aider ce qu'il puisse faire ses lacets, tre en change social, acheter le pain. Parce qu'on ne sera pas toujours l. Le Bal des pompiers , salle des fte, demain 20 h 30. Gratuit. Sans rservation. Document VOINOR0020121024e8ao000m4

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Organisation d'une confrence-dbat sur la gntique et l'autisme Correspondant 364 mots 26 octobre 2012 Midi Libre MIDLIB NARBONNE_ML Franais Copyright 2012 Midi Libre All Rights Reserved NISSAN-LEZ-ENSERUNE Dernirement, dans la salle Michel Galabru, la dlgation biterroise de la Croix Rouge et la Maison de Sol-N ont reu nombre de professionnels du monde mdical la confrence-dbat organise par le docteur Jean-Michel Amar et anime conjointement par le professeur Pierre Sarda, chef du service gntique, et le docteur David Genevive, gnticien, tous deux au CHU de Montpellier. Trois thmes ont t dvelopps : gnralits en gntique, syndrome d'Engelmann et de Willi Prader, gntique et autisme. Aprs l'accueil du Dr Amar, le Dr Genevive traita les composantes gntiques de l'autisme et le rle du gnticien dans sa prise en charge . L'autisme est 4 fois plus frquent chez les garons que chez les filles. Les dficiences de l'autisme sont caractrises par le choix des interactions sociales rciproques, la communication verbale, les activits imaginatives avec restriction des intrts associes au retard mental, aux signes neurologiques et anomalies morphologiques et dysmorphiques. Le syndrome de Willi Prader se caractrise la naissance par une hypotonie svre avec des difficults alimentaires, suivie par l'hyperphagie, responsable du dveloppement d'une obsit morbide. Le syndrome d'Engelmann, trouble trs svre du dveloppement neurologique d'origine gntique, est caractris par un retard svre du dveloppement : retard mental, dficit important de la parole et comportement caractristique. Les enfants sont trs joyeux riant de faon inapproprie. Le professeur Sarda commente l' Autisme ou plus gnralement les troubles du spectre autistique (TSA) un trouble du comportement humain caractris par une interaction sociale et une communication anormales, avec des comportement restreints et rptitifs. L'autisme affecte la faon dont le cerveau traite les informations en modifiant de
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manire encore non connue l'organisation des rseaux de neurones durant le dveloppement. Les symptmes sont gnralement dtects par les parents ds les deux premires annes de la vie de l'enfant. La classification internationale distingue en parlant d'autisme : l'autisme infantile, le syndrme d'Asperger, l'autisme atypique. En 2012 l'autisme a t dclar grande cause nationale en France. Les thmes dbattus, les invits ont partag le succulent buffet de Nicolas Cabrol. Document MIDLIB0020121026e8aq000bi

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Ploudalmzeau Maison d'accueil spcialise : le chantier avance grands pas 375 mots 26 octobre 2012 Ouest France OUESTF brest Franais Ouest France 2012. Le projet Fin 2013, la premire Maison d'accueil spcialise (MAS) du Pays de Brest ouvrira ses portes Ploudalmzeau. Le chantier avance bien. Ce mardi, partenaires du projet, familles de futurs rsidents ou encore voisins avaient t convis une visite du chantier. Ce projet est men par l'association Les Gents d'or qui, tout au long de son laboration, a travaill en troite collaboration avec le centre de ressources Autisme Bretagne et le cabinet d'architectes Gohier. La ralisation des 2 700 m2 de construction a t prise en charge par Brest Mtropole Habitat. Construire est leur mtier, pas le ntre ! remarquait Yannick Arzel, directeur du futur tablissement. Pour polyhandicaps et autistes Cette nouvelle structure est appele accueillir 25 personnes en situation de polyhandicap et 15 personnes souffrant d'autisme . Soixante salaris (personnels de sant, administratif, techniques) assureront son bon fonctionnement. Une infirmire sera prsente 24 heures/24, ce qui permettra de limiter les recours hospitalisation se rjouit le directeur. L'tablissement comprendra deux zones. L'une destine aux patients autistes pour lesquels il est important de limiter les stimulations : chambres plus petites, espaces communs disposant d'alvoles pour s'isoler, etc. La zone rserve aux polyhandicaps proposera, quant elle, des dimensions plus larges, de faon pouvoir voluer dans de bonnes conditions avec les fauteuils roulants, lits mdicaliss et
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autres quipements. La moiti des places dj attribue Sur les 40 places disponibles, une vingtaine a dj t attribue. Il s'agit de dossiers concernant des personnes actuellement hberges dans des structures pour adultes ou dont les familles attendaient avec impatience une possibilit de rapprochement gographique. Nous avons beaucoup apprendre de vos comptences de parents remarquait Yannick Arzel qui a dj rencontr plusieurs reprises ces familles. Aprs la visite du chantier, Jean-Pierre Phelippeau, directeur gnral des Gents d'or, devait souligner que s'il leur est parfois difficile de s'implanter sur un territoire, Ploudalmzeau, on ne parle plus d'intgration mais d'inclusion, tant la personne handicape a sa place dans la cit ! . Ce projet est financ principalement par l'Agence rgionale de sant, tant au niveau de la construction que du fonctionnement. Document OUESTF0020121026e8aq000d1

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Saint-Malo Ville L'autisme, ils en ont parl ensemble 338 mots 26 octobre 2012 Ouest France Ouest France 2012. Un forum sur l'autisme s'est tenu la Maison de la famille. Parole tait donne aux malades et leurs familles. L'un d'eux tmoigne. Un tat des lieux a permis de rvler que 53 enfants (40 garons et 13 filles) taient identifis comme autistes typiques, sur le pays de Saint-Malo. Virgil, 21 ans, est l'un d'eux. Il tmoigne. Quand j'tais petit, je courais partout, mais je ne sais pas pourquoi, car j'tais autiste. Je suis all l'cole 10 ans. Mon parcours au collge a t trs difficile. Je n'ai pas pu aller dans le collge de ma ville, car ils ne voulaient pas d'handicaps, donc pas d'embrouille. Mais, j'ai quand mme eu mon brevet des collges et je suis rentr au lyce. J'ai fait une seconde bac pro comptabilit. Au dbut, je ne communiquais pas avec les lves. partir de la premire, je commenais communiquer avec les autres. Je comprenais leur conversation et je me suis fait un peu de copains. J'ai ressenti de la joie et, avec l'aide de Stphan et de Maud, mes AVS (Auxiliaire de vie scolaire), qui m'ont beaucoup aid, j'ai eu mon bac avec une mention bien. Aprs, j'ai suivi un BTS CGO premire anne. C'tait trs difficile, a allait trop vite. Aujourd'hui, j'ai plus d'analyse qu'avant. Pour l'instant, je reste avec mes parents, pour russir mon indpendance plus tard. J'ai pris de l'autonomie et je ralise beaucoup de choses seul : cuisine, courses, matchs de foot, cours de code, bibliothque, tennis de table que je pratique en comptition. Pour l'avenir, j'adore les chiffres et la comptabilit, et j'ai une excellente mmoire. Je recherche un emploi d'aide comptable. Je suis autiste, mais je fais beaucoup d'efforts pour entrer dans votre monde, alors n'oubliez pas le mien ! Document OUESTF0020121026e8aq001zc
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Ergu-Gabric Enfants autistes : Je ne trouve pas que je suis diffrente Recueilli par 571 mots 26 octobre 2012 Ouest France OUESTF quimper Franais Ouest France 2012. La semaine de l'autisme se tient jusqu' demain Ergu-Gabric. L'occasion de dcouvrir, de l'intrieur, la vie de certains enfants autistes. Est-ce difficile de vivre auprs des autres ? Se sentent-ils diffrents ? Ils rpondent ces questions, accompagns de leurs mamans. Adrien, 10 ans, Je vais l'cole comme les autres. Je suis seulement un petit peu diffrent. Les autres enfants arrivent rester plus calmes que moi. Une auxiliaire de vie scolaire m'accompagne. C'est la matresse qui a expliqu la classe que j'tais autiste et ce que a voulait dire. Quand un nouvel lve handicap est arriv l'cole, j'ai tout de suite dit que moi aussi j'tais handicap. Moi, a ne me drange pas que les autres le savent. Mes copains, a leur est gal. J'ai un peu plus de mal l'crit, je prfre l'oral. Zanna, maman d'Adrien Nous avons appris l'autisme d'Adrien assez tard. Il avait dj 7 ans. Avant, on ne savait pas ce qu'il avait. On se posait beaucoup de questions : pourquoi il n'obit jamais ? Qu'est-ce que l'on fait mal ? Une fois que le diagnostic a t pos, au moins on savait comment travailler, les rgles qu'il fallait respecter...
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L'autisme est un nom qui effraie, il faut alors apprhender le handicap. Ce n'est pas toujours facile car c'est invisible. La famille ne nous croit pas, ne comprend pas. Gabriella (1), 13 ans Je suis scolarise normalement et je ne trouve pas que je suis diffrente. J'ai une vraie bande de copains mais je n'ai pas envie de le leur dire. Car les autres ne comprennent pas et c'est compliqu expliquer. Je l'ai dit une fois, mais on m'a dit que je mentais car, pour eux, les autistes ne parlent pas. Avant d'tre diagnostique, je pleurais tous les soirs, je ne voulais pas aller l'cole. Aujourd'hui, tout va mieux. Marie (1), maman de Gabriella La cour de rcr, c'est parfois le champ de foire. C'est en se faisant des amis que les autistes apprennent les relations sociales mais ils ont parfois des ractions diffrentes, les autres enfants ne comprennent pas toujours. En tant que parent, on a besoin de savoir ce qu'ils ont. Il faut tomber sur les bonnes personnes, qui osent dire le mot autiste. Aprs, il faut continuer sa vie, assumer ses responsabilits. Pour les frres et soeurs, aussi, ce n'est pas vident. Ils en ont marre qu'on parle tout le temps d'autisme. Mario, 11 ans, et Nathalie, sa maman Mario est n aveugle. Nous avons appris plus tard que c'tait une des consquences de l'autisme et aujourd'hui il voit correctement. Il a fallu tout lui apprendre, la motricit, la parole... Le matin, il est scolaris normalement avec un ducateur. Il apprend seulement les mathmatiques et le franais. L'aprs-midi, il est au centre exprimental Aba. Mario aime beaucoup qu'on s'intresse lui, qu'on lui pose des questions... Il y a encore quelques annes, je n'aurai jamais pu croire qu'il puisse parler et mme compter. Il progresse normment. Elodie RAB. (1) Les prnoms ont t modifis. Document OUESTF0020121026e8aq002ds

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Dole-ville Un forum pour aborder lautisme autrement 202 mots 26 octobre 2012 Le Progrs PROGRS 21 Franais 2012 Le Progrs. Dclar cause nationale 2012, lautisme a fait lobjet dun forum, mercredi soir, salle Edgar-Faure. Organise par lassociation Lieu-Dit et lassociation pour la Cause Freudienne Bourgogne FrancheComt, cette srie de tables rondes avait pour objectif daborder lautisme sous un angle clinique renouvel. Le clinicien doit y mettre du sien, a dclar Marga Karsz-Medelenko, prsidente de Lieu-Dit, ds louverture, le sujet possde un savoir, mme sil ne parle pas. Nous laccueillons, nous laccompagnons dans sa cration. Toutes les interventions sont dailleurs alles dans ce sens. Le cas de Laura, une enfant atypique, a longuement t voqu par lquipe pluridisciplinaire qui la entoure jusqu la faire accder une sociabilit dont elle tait jusque-l absente. Jeu, musique, danse mais aussi participation des parents aux activits sont aujourdhui des pratiques qui se dveloppent. La pdopsychiatre Isabelle Chaveneau a parl dalliance thrapeutique avec les parents qui, sils viennent avec leur anxit et leur besoin de recettes, peuvent entrer dans un jeu dchange plus riche avec leur enfant dans le cadre de sances adaptes. Document PROGRS0020121026e8aq0009a

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La gntique au cur de la confrence-dbat Correspondant 428 mots 28 octobre 2012 Midi Libre MIDLIB BEZIERS Franais Copyright 2012 Midi Libre All Rights Reserved Dernirement, dans la salle Michel-Galabru, la dlgation biterroise de la Croix-Rouge et la Maison de Sol-N ont reu nombre de professionnels du monde mdical la confrence-dbat organise par le docteur Jean-Michel Amar et anime conjointement par le professeur Pierre Sarda, chef du service gntique, et le docteur, David Genevieve, gnticien, tous deux exerant au CHU de Montpellier. Trois thmes ont t dvelopps : 'gnralits en gntique' ; 'syndrome d'Engelmann et de Willi Prader' ; 'gntique et autisme'. Le chromosome 15 en cause Aprs l'accueil du Dr Amar, le Dr Genevieve traita des composantes gntiques de l'autisme et le rle du gnticien dans sa prise en charge. L'autisme est quatre fois plus frquent chez les garons que chez les filles. Les dficiences sont caractrises par le choix des interactions sociales rciproques, la communication verbale, les activits imaginatives avec restriction des intrts associes au retard mental, aux signes neurologiques et anomalies morphologiques et dysmorphiques. Le syndrome de Willi Prader se caractrise la naissance par une hypotonie svre avec des difficults alimentaires, suivie par une hyperphagie, responsable du dveloppement d'une obsit morbide. Tous les malades ont un comportement particulier avec difficults d'apprentissage. L'hypogonadisme touche les deux sexes et la taille est rduite. L'absence de la rgion PWS/AS du chromosome 15 paternel est la cause de la pathologie. Le syndrome d'Engelmann, trouble trs svre du dveloppement neurologique d'origine gntique, est caractris par un retard svre du dveloppement avec retard mental, dficit important de la parole, dmarche brieuse par ataxie crbelleuse et/ou trmulations des membres et comportement caractristique : les enfants sont trs joyeux, riant de faon inapproprie. Le docteur britannique Engelmann en dcrit les symptmes pour la premire fois en 1965. Tout comme le syndrome de Willi Prader, l'absence de la rgion PWS/AS du chromosome 15 mais maternel cette fois est la cause de la pathologie.
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Grande cause nationale en 2012 Le professeur Sarda commente l'autisme, ou plus gnralement les troubles du spectre autistique (TSA), un trouble du comportement humain caractris par une interaction sociale et une communication anormales, avec des comportements restreints et rptitifs. L'autisme affecte la faon dont le cerveau traite les informations en modifiant de manire encore non connue l'organisation des rseaux de neurones durant le dveloppement. Les symptmes sont gnralement dtects par les parents ds les deux premires annes de la vie de l'enfant. Notez qu'en 2012, l'autisme a t dclar grande cause nationale en France. Document MIDLIB0020121028e8as000ke

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Autisme : la vie autrement 707 mots 29 octobre 2012 News Press NPRESS Franais (c) Copyright News Press 2012. Tous droits reserves. Association Perce-Neige De nombreux clichs illustrent notre vision de l'autisme. Etres surdous ou totalement renferms sur euxmmes, les autistes ont de multiples visages. Ils peuvent fasciner comme drouter. Camille Blossier, conseillre technique au sein de Perce-Neige, nous donne les cls de cet univers inaccessible. "L'autisme a t dcrit en 1943 par le Docteur Lo Kanner. Il tait jusqu'alors considr comme une psychose infantile. Actuellement, on l'identifie au travers d'un trouble principal : le trouble majeur de la communication et des interactions sociales. Pour tre qualifis d'autistiques, ces troubles doivent tre prsents et constats avant l'ge de 3 ans. Aujourd'hui encore, les causes de l'autisme restent mystrieuses. La piste gntique semble toutefois tre la plus vraisemblable. La personne autiste n'est pas en mesure de dcoder spontanment le langage, qu'il soit oral ou gestuel. Il ne peut donc pas y rpondre. Evidemment, ce handicap se manifeste diffremment selon les sujets. Certaines personnes sont totalement replies sur elles-mmes, enfermes dans des strotypies gestuelles ou phoniques. D'autres bnficient d'une relative autonomie. Enfin, il existe le 'syndrome d'Asperger' : les personnes touches sont d'une intelligence rare avec un talent exceptionnel dans un domaine trs prcis. Un comportement domin par l'angoisse Les autistes sont trs angoisss. Combine leur difficult communiquer, cette anxit peut parfois gnrer des troubles du comportement. L'inattendu les plongeant dans un grand dsarroi, ils peuvent parfois se faire mal ou faire mal aux autres. L'apprentissage d'un mtier est trs rare chez les autistes. Il
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existe des exemples bien sr, notamment chez les personnes touches par le 'syndrome d'Asperger'. Parmi ces autistes d'exception, on pense Temple Grandin. Cette femme a en effet russi dcrocher un doctorat en sciences du comportement animal et enseigner l'universit du Colorado ! Oliver Sacks s'est d'ailleurs intress son parcours dans son ouvrage Un anthropologue sur Mars." La question rituelle "et aprs ?" "Les personnes autistes sont incapables d'anticiper. Cela les angoisse terriblement. Lors de leur intgration dans une Maison Perce-Neige, l'quipe encadrante a pour objectif d'organiser l'aprs', les aider s'orienter, se reprer dans le temps comme dans l'espace. Selon les rsidents, l'intgration dans une Maison Perce-Neige demande un temps d'adaptation plus ou moins long. Ils ont besoin de repres forts dans leur cadre de vie, leurs rapports avec les autres, leurs activits. Certains autistes se sentiront vraiment mal tant qu'ils n'auront pas trouv ces marques. Nous veillons galement surveiller leur tendance aux strotypies. Elles se manifestent par exemple par des balancements d'avant en arrire ou par l'utilisation d'objets dtourns de leur usage premier. Les autistes peuvent ainsi fixer du regard pendant un long moment le hublot d'une machine laver en marche. Ces actions 'en boucle' leur permettent quasiment de 's'hypnotiser', de combler leur angoisse du vide et par consquent de se calmer. Ils ne doivent toutefois pas s'enfermer dans ce cycle d'autostimulation au risque de ne plus faire que cela. Des tudes amricaines ont avanc l'hypothse que les autistes recevraient toutes les informations ambiantes d'un seul coup. N'ayant pas la capacit de les trier et de les hirarchiser, ils seraient en fait 'sur-stimuls', saturs d'informations. Ils immobiliseraient alors les lments qu'ils peuvent identifier. Cette hypothse expliquerait leur rsistance au changement." Plus jamais de "souffrance sur la souffrance "Grce au travail quotidien des ducateurs, certains autistes gagnent en autonomie. Certains loisirs, comme le dessin, leur offrent l'opportunit de s'exprimer et de librer leur sensibilit intriorise. En parallle de ce travail, nous veillons accompagner du mieux possible les familles. Elles ont longtemps eu un rapport tendu avec la mdecine. Pour expliquer les causes de l'autisme, on a souvent point du doigt une mauvaise relation parents/enfant (mre/enfant en particulier). Cette mprise a ajout de la souffrance sur la souffrance. Les parents ne doivent plus jamais tre traits ainsi. A Perce-Neige, nous avons toujours l'esprit l'accompagnement des familles. Cela fait partie de notre mission. " FR259548
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Saint-Galmier-rgion Veauche La France accuse, dans le domaine de la prise en charge, un srieux retard 257 mots 29 octobre 2012 Le Progrs PROGRS 23 Franais 2012 Le Progrs. Des yeux extraordinaires, une vivacit et une ptillance toute preuve, Lna est une petite fille trs attachante. Atteinte dautisme, elle saccroche face de nombreuses difficults: acquisitions scolaires, langage, etc. Ses parents, Sverine et Stphane Dumas ont cr lassociation Lna avance. Rencontre. Cette anne, Lna est en sur-maintien en grande section de maternelle aux Glycines. Mme Levet, directrice et enseignante, est extraordinaire avec elle. Lna est prise en charge, orthophonie, psychomotricit, etc., mais ce nest pas suffisant. Depuis 3 ans, elle bnficie dune ducatrice spcialise avec la mthode ABA. Elle la rencontre une fois par semaine domicile et aussi lcole. Mais tout cela a un cot notre charge et lassociation a pour but de recueillir des fonds indispensables la prise en charge de Lna dans le cadre de lABA. Cest une mthode comportementale qui est individualise afin de rpondre aux besoins de chacun. Elle donne les bases dune prise en charge utiliser dans la vie de tous les jours: difficults face aux comportements, acquisitions scolaires, meilleure autonomie, etc. La France accuse dans ce domaine un srieux retard. Lassociation est rcente. Une pice de thtre a t joue Savigneux et dans lt, Mickal Jones est venu jouer Saint-Romain-le-Puy. Un chque a t remis et nous avons pu faire connatre lassociation ce moment-l.

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Document PROGRS0020121029e8at000a2

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Mauriac Le bonhomme de l'ombre, roman sur l'autisme de Maurice Coudy 356 mots 29 octobre 2012 La Montagne LAMONT La Montagne-Cantal; La Montagne-Tulle Franais Copyright 2012. Centre France. All Rights Reserved. Le bonhomme de l'ombre , un roman sur l'autisme sign Maurice Coudy. Maurice Coudy qui habite actuellement dans les environs de Bort-les-Orgues vient de signer un roman sur l'autisme intitul Le bonhomme de l'ombre. Prsentation. Question : Pourquoi avez-vous choisi d'crire un roman sur l'autisme ? Le bonhomme de l'ombre est avant tout un roman sur la vie et l'histoire d'un couple qui se voit confront, au travers de l'enfant qu'il a eu, l'autisme. Question : Vous avez dirig pendant plus de 27 ans l'tablissement de Peyrelevade qui accueille des enfants difficiles, psychotiques et autistes. Votre exprience et ce temps pass auprs d'eux vous a-t-il inspir ? Rien ne remplace l'exprience! Auprs des enfants mais aussi en rencontrant chaque fois que la demande m'en tait faite les parents. Car si rien n'est facile pour ces enfants difficiles, aux comportements tranges, surprenants, dfiant toute logique, rien n'est facile non plus pour les parents. Ils ont besoin d'tre couts et soutenus. Les parents doivent tre des partenaires, vcus comme tels par toute l'institution. Toutes les forces, toutes les comptences, tous les savoirs mme les plus intuitifs doivent converger vers une prise en charge scurisante, empreinte d'un profond humanisme et avec beaucoup de respect et d'humilit. C'est le vcu, la confrontation au quotidien, la scurit matrielle et affective, en quelque sorte
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l'exprience, qui nous autorise parler un peu de l'autisme. Voil pourquoi j'ai eu envie d'crire ce roman. Le bonhomme de l'ombre , dans cette belle aventure amoureuse, vient heurter les liens positifs qui unissent cet homme et cette femme jusqu' rendre difficile voire impossible une vie commune. Mais je ne vous dvoilerai pas la fin. Le rsum serait trop imparfait. Question : Comment se procurer le livre ? Il suffit de me tlphoner au 06.72.12.20.34. Le livre cote 12 ?. Le bonhomme de l'ombre , un roman sur l'autisme sign Maurice Coudy. Document LAMONT0020121029e8at0005z

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Developmental Neuroscience; New Findings from University of California Describe Advances in Developmental Neuroscience 410 mots 26 octobre 2012 Genomics & Genetics Weekly GEWK 64 Anglais (c) Copyright 2012 Genomics & Genetics Weekly via NewsRx.com 2012 OCT 26 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -Fresh data on Developmental Neuroscience are presented in a new report. According to news reporting out of Los Angeles, California, by NewsRx editors, research stated, "Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental disorders that are characterized by deficits in social interaction, verbal and nonverbal communication, and restrictive interests and repetitive behaviors. While human genetic studies have revealed marked heritability in ASD, it has been challenging to translate this genetic risk into a biological mechanism that influences brain development relevant to the disorder phenotypes." Our news journalists obtained a quote from the research from the University of California, "This is partly due to the complex genetic architecture of ASD, which involves de novo gene mutations, genomic abnormalities, and common genetic variants. Rather than trying to reconstitute the clinical disorder, using genetic model animals to examine specific features of core ASD pathophysiology offers unique opportunities for refining our understanding of neurodevelopmental mechanisms in ASD. A variety of ASD-relevant phenotypes can now be investigated in rodents, including stereotyped and repetitive behaviors, and deficits in social interaction and communication. In this review, we focus on several prevailing mouse models and discuss how studies have advanced our understanding of synaptic mechanisms that may underlie ASD pathophysiology." According to the news editors, the research concluded: "Although synaptic perturbations are not the only alterations relevant for ASD, we reason that understanding the synaptic underpinnings of ASD using mouse models may provide mechanistic insights into its etiology and lead to novel therapeutic and interventional strategies." For more information on this research see: Modeling of Autism Genetic Variations in Mice: Focusing on Synaptic and Microcircuit Dysfunctions. Developmental Neuroscience, 2012;34(2-3):88-100.

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Neuroscience; Researchers from King's College Publish New Studies and Findings in the Area of Neuroscience 298 mots 26 octobre 2012 Genomics & Genetics Weekly GEWK 170 Anglais (c) Copyright 2012 Genomics & Genetics Weekly via NewsRx.com 2012 OCT 26 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -Investigators publish new report on Neuroscience. According to news reporting out of London, United Kingdom, by NewsRx editors, research stated, "Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by repetitive behaviours and restricted interests, impairments in social behaviour and relations, and in language and communication. These symptoms are also observed in a number of developmental disorders of known origin, including Fragile X Syndrome, Rett Syndrome, and Foetal Anticonvulsant Syndrome." Our news journalists obtained a quote from the research from King's College, "While these conditions have diverse etiologies, and poorly understood pathologies, emerging evidence suggests that they may all be linked to dysfunction in particular aspects of GABAergic inhibitory signalling in the brain. We review evidence from genetics, molecular neurobiology and systems neuroscience relating to the role of GABA in these conditions." According to the news editors, the research concluded: "We conclude by discussing how these deficits may relate to the specific symptoms observed." For more information on this research see: GABA system dysfunction in autism and related disorders: From synapse to symptoms. Neuroscience and Biobehavioral Reviews, 2012;36(9):2044-55. (Elsevier www.elsevier.com; Neuroscience and Biobehavioral Reviews www.elsevier.com/wps/product/cws_home/831) Our news journalists report that additional information may be obtained by contacting S. Coghlan, King's College London, Dept. of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK.
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Autism; Recent Findings from University of Utah Highlight Research in Autism 557 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 49 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Current study results on Autism have been published. According to news reporting originating in Salt Lake City, Utah, by NewsRx journalists, research stated, "Group differences in resting state functional magnetic resonance imaging connectivity between individuals with autism and typically developing controls have been widely replicated for a small number of discrete brain regions, yet the whole-brain distribution of connectivity abnormalities in autism is not well characterized. It is also unclear whether functional connectivity is sufficiently robust to be used as a diagnostic or prognostic metric in individual patients with autism." The news reporters obtained a quote from the research from the University of Utah, "We obtained pairwise functional connectivity measurements from a lattice of 7266 regions of interest covering the entire grey matter (26.4 million connections) in a well-characterized set of 40 male adolescents and young adults with autism and 40 age-, sex-and IQ-matched typically developing subjects. A single resting state blood oxygen level-dependent scan of 8 min was used for the classification in each subject. A leave-oneout classifier successfully distinguished autism from control subjects with 83% sensitivity and 75% specificity for a total accuracy of 79% (p=1.1 x 10(-7)). In subjects <20 years of age, the classifier performed at 89% accuracy (p=5.4 x 10(-7)). In a replication dataset consisting of 21 individuals from six families with both affected and unaffected siblings, the classifier performed at 71% accuracy (91% accuracy for subjects <20 years of age). Classification scores in subjects with autism were significantly correlated with the Social Responsiveness Scale (p=0.05), verbal IQ (p=0.02) and the Autism Diagnostic Observation Schedule-Generic's combined social and communication subscores (p=0.05). An analysis of informative connections demonstrated that region of interest pairs with strongest correlation values were most abnormal in autism. Negatively correlated region of interest pairs showed higher correlation in autism (less anticorrelation), possibly representing weaker inhibitory connections, particularly for long connections (Euclidean distance >10 cm). Brain regions showing greatest differences included regions of the default mode network, superior parietal lobule, fusiform gyrus and anterior insula. Overall,
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classification accuracy was better for younger subjects, with differences between autism and control subjects diminishing after 19 years of age. Classification scores of unaffected siblings of individuals with autism were more similar to those of the control subjects than to those of the subjects with autism." According to the news reporters, the research concluded: "These findings indicate feasibility of a functional connectivity magnetic resonance imaging diagnostic assay for autism." For more information on this research see: Functional connectivity magnetic resonance imaging classification of autism. Brain, 2011;134(Pt 12):3742-54. (Oxford University Press - www.oup.com/; Brain - brain.oxfordjournals.org) Our news correspondents report that additional information may be obtained by contacting J.S. Anderson, Dept. of Neuroradiology, University of Utah, 1A71 School of Medicine, Salt Lake City, UT 84132, United States. Keywords for this news article include: Utah, Brain, Autism, Neurology, United States, Salt Lake City, Central Nervous System, North and Central America, Developmental Disabilities. Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC Document MHWK000020121026e8at00012

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Autism and Developmental Disorders; Research Conducted at MIND Institute Has Provided New Information about Autism and Developmental Disorders 476 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 55 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Research findings on Autism and Developmental Disorders are discussed in a new report. According to news reporting out of Sacramento, California, by NewsRx editors, research stated, "Autism is a neurodevelopmental disorder consisting of a constellation of symptoms that sometimes occur as part of a complex disorder characterized by impairments in social interaction, communication and behavioral domains. It is a highly disabling disorder and there is a need for treatment targeting the core symptoms." Our news journalists obtained a quote from the research from MIND Institute, "Although autism is accepted as highly heritable, there is no genetic cure at this time. Autism is shown to be linked to several genes and is a feature of some complex genetic disorders, including fragile X syndrome (FXS), fragile X premutation involvement, tuberous sclerosis and Rat syndrome. The term autism spectrum disorders (ASDs) covers autism, Asperger syndrome and pervasive developmental disorders (PDD-NOS) and the etiologies are heterogeneous. In recent years, targeted treatments have been developed for several disorders that have it known specific genetic cause leading to autism. Since there are significant molecular and neurobiological overlaps among disorders, targeted treatments developed for a specific disorder may be helpful in ASD of unknown etiology. Examples of this are two drug classes developed to treat FXS, Arbaclofen, a GABA(B) agonist, and mGluR5 antagonists, and both may be helpful in autism without FXS. The mGluR5 antagonists are also likely to have a benefit in the aging problems of fragile X premutation carriers, the fragile X-associated tremor ataxia syndrome (FXTAS) and the Parkinsonism that can occur in aging patients with fragile X syndrome." According to the news editors, the research concluded: "Targeted treatments in FXS which has a well known genetic etiology may lead to new targeted treatments in autism." For more information on this research see: Targeted treatments in autism and fragile X syndrome.
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Research in Autism Spectrum Disorders, 2012;6(4):1311-1320. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders www.elsevier.com/wps/product/cws_home/709651) Our news journalists report that additional information may be obtained by contacting C.K. Gukan, UC Davis Med Center, MIND Inst, Sacramento, CA 95817, United States. Keywords for this news article include: Genetics, Sacramento, California, United States, Fragile X Syndrome, Nervous System Diseases, Congenital Abnormalities, Sex Chromosome Disorders, North and Central America, Neurologic Manifestations, Developmental Disabilities, X-Linked Mental Retardation, Neurobehavioral Manifestations, Autism and Developmental Disorders Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC Document MHWK000020121026e8at00019

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Autism; Research Findings from University Hospital Update Understanding of Autism 394 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 56 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Researchers detail new data in Autism. According to news originating from Lille, France, by NewsRx correspondents, research stated, "Corpus callosum abnormalities are common brain malformations with a wide clinical spectrum ranging from severe intellectual disability to normal cognitive function. The etiology is expected to be genetic in as much as 30-50% of the cases, but the underlying genetic cause remains unknown in the majority of cases." Our news journalists obtained a quote from the research from University Hospital, "By next-generation mate-pair sequencing we mapped the chromosomal breakpoints of a patient with a de novo balanced translocation, t(1; 6)(p31; q25), agenesis of corpus callosum (CC), intellectual disability, severe speech impairment, and autism. The chromosome 6 breakpoint truncated ARID1B which was also truncated in a recently published translocation patient with a similar phenotype. Quantitative polymerase chain reaction (Q-PCR) data showed that a primer set proximal to the translocation showed increased expression of ARID1B, whereas primer sets spanning or distal to the translocation showed decreased expression in the patient relative to a non-related control set. Phenotype-genotype comparison of the translocation patient to seven unpublished patients with various sized deletions encompassing ARID1B confirms that haploinsufficiency of ARID1B is associated with CC abnormalities, intellectual disability, severe speech impairment, and autism." According to the news editors, the research concluded: "Our findings emphasize that ARID1B is important in human brain development and function in general, and in the development of CC and in speech development in particular." For more information on this research see: Corpus callosum abnormalities, intellectual disability, speech impairment, and autism in patients with haploinsufficiency of ARID1B. Clinical Genetics, 2012;82(3):248255. Clinical Genetics can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ,
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Autism; Research from University of California in the Area of Autism Published 369 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 61 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Investigators publish new report on Autism. According to news originating from Davis, California, by NewsRx correspondents, research stated, "We employed a multi-scale clustering methodology known as 'data cloud geometry' to extract functional connectivity patterns derived from functional magnetic resonance imaging (fMRI) protocol. The method was applied to correlation matrices of 106 regions of interest (ROIs) in 29 individuals with autism spectrum disorders (ASD), and 29 individuals with typical development (TD) while they completed a cognitive control task." Our news journalists obtained a quote from the research from the University of California, "Connectivity clustering geometry was examined at both 'fine' and 'coarse' scales. At the coarse scale, the connectivity clustering geometry produced 10 valid clusters with a coherent relationship to neural anatomy. A supervised learning algorithm employed fine scale information about clustering motif configurations and prevalence, and coarse scale information about intra-and inter-regional connectivity; the algorithm correctly classified ASD and TD participants with sensitivity of [Formula: see text] and specificity of [Formula: see text]. Most of the predictive power of the logistic regression model resided at the level of the fine-scale clustering geometry, suggesting that cellular versus systems level disturbances are more prominent in individuals with ASD." According to the news editors, the research concluded: "This article provides validation for this multi-scale geometric approach to extracting brain functional connectivity pattern information and for its use in classification of ASD." For more information on this research see: Extracting multiscale pattern information of FMRI based functional brain connectivity with application on classification of autism spectrum disorders. Plos One, 2012;7(10):e45502. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

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Autism; Research on Autism Detailed by Investigators at Louisiana State University 364 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 62 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- New research on Autism is the subject of a report. According to news reporting from Baton Rouge, Louisiana, by NewsRx journalists, research stated, "The use of applied behavior analysis (ABA) to treat persons with autism goes back several decades. Many specific target behaviors and intervention strategies have been developed." The news correspondents obtained a quote from the research from Louisiana State University, "In the last two decades the most heavily studied of these methods has been Early Intensive Behavioral Interventions (EIBI). This package of ABA methods is unique in two ways. First, a broad range of target behaviors are trained for 20-40 h per week. This training is much more treatment per week than what is described in most ABA studies. Second, the children treated are typically 2-3 years of age, which is younger than for most ABA research. Reviews of EIBI have typically focused on the efficacy of the methods. These are important, but at present we argue that these methods are effective." According to the news reporters, the research concluded: "This paper is different in that it looks at current trends such as generalization, parent training, factors that mitigate against effective treatment and the need for follow-up and booster treatment." For more information on this research see: Trends and topics in Early Intensive Behavioral Interventions for toddlers with autism. Research in Autism Spectrum Disorders, 2012;6(4):1412-1417. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651) Our news journalists report that additional information may be obtained by contacting J.L. Matson, Louisiana State University, Dept. of Psychol, Baton Rouge, LA 70803, United States.
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Autism; Findings from University of Connecticut Provide New Insights into Autism 355 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 105 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Investigators publish new report on Autism. According to news reporting out of Storrs, Connecticut, by NewsRx editors, research stated, "Grammar is frequently considered to be a strength in the cognitive profile of individuals with autism spectrum disorders (ASDs); however, few studies have investigated how abstract (i.e. distinct from specific lexical items) is the grammatical knowledge of individuals with ASD. In this study, we examine the extent to which children with ASD have abstracted the transitive (SVO) frame in English." Our news journalists obtained a quote from the research from the University of Connecticut, "Participants in a longitudinal study of language acquisition in children with autism (17 children with ASD averaging 41 months of age, 18 TD children averaging 28 months of age) were taught two novel verbs in transitive sentences and asked (via intermodal preferential looking) whether these verbs mapped onto novel causative vs. noncausative actions. Both groups consistently mapped the verbs onto the causative actions (i.e. they engaged in syntactic bootstrapping). Moreover, the children with ASD's performance on this task was significantly and independently predicted by both vocabulary and sentence-processing measures obtained 8 months earlier." According to the news editors, the research concluded: "We conclude that many children with ASD are able to generalize grammatical patterns, and this ability may derive from earlier lexical and grammatical knowledge." For more information on this research see: Abstractness and continuity in the syntactic development of young children with autism. Autism Research, 2011;4(6):422-37. (Wiley-Blackwell - www.wiley.com/; Autism Research - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1939-3806)

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Autism; Investigators at Sapienza University Publish Research in Autism 306 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 111 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Investigators publish new report on Autism. According to news reporting out of Rome, Italy, by NewsRx editors, research stated, "The aim of the present article is to critically review the experimental research in the domain of metaphor and metonymy competencies in Autism Spectrum Disorders (ASD) children." Our news journalists obtained a quote from the research from Sapienza University, "After providing some basic definitions of metaphor and metonymy, we consider some major points emerging from studies on metaphorical and metonymical competencies in typical child development. Then, we review a number of emblematic studies concerning the relationship between autism and metaphor and metonymy, starting from the pioneering clinical studies by Kanner and Asperger in the 1940s, We also critically analyze experimental research on these same topics starting from the 1990s." According to the news editors, the research concluded: "The discussion highlights some major points emerging from recent experimental research and outlines possible perspectives for future research." For more information on this research see: Metaphor and metonymy in ASD children: A critical review from a developmental perspective. Research in Autism Spectrum Disorders, 2012;6(4):1289-1296. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651) Our news journalists report that additional information may be obtained by contacting S. Melogno, Roma La Sapienza University, Dept. of Psychol Dev & Socialisat Proc, I-00185 Rome, Italy. Keywords for this news article include: Rome, Italy, Europe, Autism, Pediatrics

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Autism; Investigators from California State University Zero in on Autism 404 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 112 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Current study results on Autism have been published. According to news reporting originating from San Bernardino, California, by NewsRx correspondents, research stated, "A literature review completed by Bauer and Blunden (2008) determined that compared to objective measures, subjective assessments of sleep for typically developing children (e.g., parental reports) were of limited utility. No comparable literature review has been undertaken to determine whether subjective measures are appropriate for assessing sleep in children with autism spectrum disorders (ASD)." Our news editors obtained a quote from the research from California State University, "Such a review is necessary as children with ASD have more sleep problems than typically developing children and children's sleep difficulties can negatively affect the child and other family members. It is, therefore, important to have measures of sleep for children with ASD that can reliably detect sleep problems and track improvements in sleep. This literature review described frequently used measures of children's sleep and evaluated their utility for assessing sleep in children with ASD. It was determined that, with the exception of sleep latency, parents' reports of children's sleep are not consistently associated with objective measures of children's sleep. This was true for single-item parent-reports and for a widely used multi-item parent-report measure of children's sleep." According to the news editors, the research concluded: "Limitations of objective sleep measures (e.g., polysomnography, actigraphy), including the inability of children with ASD to tolerate such methods, are described." For more information on this research see: Methods for assessing sleep in children with autism spectrum disorders: A review. Research in Autism Spectrum Disorders, 2012;6(4):1337-1344. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651)
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Autism; New Autism Findings from Centers for Disease Control and Prevention Published 306 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 123 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- New research on Autism is the subject of a report. According to news reporting originating from Hyattsville, Maryland, by NewsRx correspondents, research stated, " Data from the 2011 Survey of Pathways to Diagnosis and Services The median age when school-aged children with special health care needs (CSHCN) and autism spectrum disorder (ASD) were first identified as having ASD was 5 years. Schoolaged CSHCN identified as having ASD at a younger age (under age 5 years) were identified most often by generalists and psychologists, while those identified later (aged 5 years and over) were identified primarily by psychologists and psychiatrists." Our news editors obtained a quote from the research from Centers for Disease Control and Prevention, "Nine out of 10 school-aged CSHCN with ASD use one or more services to meet their developmental needs. Social skills training and speech or language therapy are the most common, each used by almost three-fifths of these children." According to the news editors, the research concluded: "More than one-half of school-aged CSHCN with ASD use psychotropic medication." For more information on this research see: Diagnostic History and Treatment of School-aged Children with Autism Spectrum Disorder and Special Health Care Needs. Nchs Data Brief, 2012;(97):1-8. The news editors report that additional information may be obtained by contacting B. Pringle, Centers for Disease Control and Prevention National Center for Health Statistics 3311 Toledo Road, Hyattsville, Maryland 20782, United States. Keywords for this news article include: Autism, Maryland, Neurology, Pediatrics, Hyattsville, United States, North and Central America, Developmental Disabilities.
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Autism; New Autism Research Reported from Ohio State University 315 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 123 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- A new study on Autism is now available. According to news reporting out of Columbus, Ohio, by NewsRx editors, research stated, "Anxiety disorders are among the most common comorbid conditions in children and adolescents with autism spectrum disorders (ASDs), although assessment presents unique challenges. Many symptoms of anxiety appear to overlap with common presentations of autism." Our news journalists obtained a quote from the research from Ohio State University, "Furthermore, deficits in language and cognitive functioning make it difficult for such children to convey their emotional states accurately. A comprehensive review of the recent literature was conducted to assay the types and rates of use of tools for evaluating anxiety symptoms in children and adolescents with ASDs." According to the news editors, the research concluded: "We identified strengths and weaknesses in existing scales, identified instruments that (although imperfect) seem to have a good coverage for youngsters with ASDs, recommended strategies for studying anxiety in these youth, and offered suggestions for future scale development." For more information on this research see: Assessment of anxiety in children and adolescents with autism spectrum disorders. Research in Autism Spectrum Disorders, 2012;6(4):1345-1365. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651) Our news journalists report that additional information may be obtained by contacting S.N. Grondhuis, Ohio State University, Columbus, OH 43210, United States.

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Autism; Research Results from Washington State University Update Understanding of Autism 392 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 183 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Current study results on Autism have been published. According to news originating from Pullman, Washington, by NewsRx editors, the research stated, "Children with autism fail to imitate from an early age and this lack of imitation is a salient diagnostic marker for the disorder. For children with Autism Spectrum Disorder (ASD), increased imitation skills appear to be related to increased skill development in a variety of areas." Our news journalists obtained a quote from the research from Washington State University, "Video modeling was recently validated as a technique to support imitation acquisition in young children with autism. The purpose of this research was to determine if there is a functional relation between caregiver implemented Video Modeling Imitation Training (VMIT) via iPad and increased imitation skills in young children with autism. In addition, a secondary analysis of language development after exposure to VMIT was also conducted. A multiple baseline design across four caregivers and their children with autism was implemented. Results indicated that all four caregivers were able to successfully create video models on an iPad when provided with minimal training and implement VMIT with fidelity for their children. All four children made substantial gains in their imitation skills during caregiver implemented treatment. Imitation skills maintained post treatment and, to varying degrees, generalized to imitation of live models." According to the news editors, the research concluded: "Expressive language skills increased to varying degrees for all participants." For more information on this research see: Teaching caregivers to implement video modeling imitation training via iPad for their children with autism. Research in Autism Spectrum Disorders, 2012;6(4):13891400. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651)
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Autism and Developmental Disorders; Research from Michigan State University Provides New Data about Autism and Developmental Disorders 405 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 186 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Researchers detail new data in Autism and Developmental Disorders. According to news originating from East Lansing, Michigan, by NewsRx correspondents, research stated, "Proponents of the verbal behavior approach to instruction for individuals with autism have identified mand training as a starting point for early intervention. Mand training is a process whereby the learner is taught to request highly preferred items under conditions when those items are most valuable." Our news journalists obtained a quote from the research from Michigan State University, "A hypothesized benefit of this approach is that mand training has a collateral effect on nontargeted behavior, though empirical support for this hypothesis is currently tenuous. The present investigation examined the collateral effects of vocal mand training compared to vocal request training for 3 previously nonvocal children with autism. Levels of orienting toward a speaker, compliance with instruction, and overall problem behavior were measured across experimental conditions and analyzed using an alternating treatment design. Results indicate that problem behavior for all participants occurred at lower levels during mand training than request training and that the level of nontargeted social behavior (i.e., orienting and compliance) was higher during mand training for 2 participants and was similar across both conditions for the final participant." According to the news editors, the research concluded: "The results support the hypothesis that mand training can have a collateral impact on nontargeted behavior, though explicit instruction of social behaviors may also need to be embedded within mand training procedures." For more information on this research see: Collateral effects of mand training for children with autism. Research in Autism Spectrum Disorders, 2012;6(4):1366-1376. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon,
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England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders -

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Pediatrics; Researchers at Evelina Children's Hospital Target Pediatrics 330 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 204 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- New research on Pediatrics is the subject of a report. According to news reporting from London, United Kingdom, by NewsRx journalists, research stated, "Background Children and young people with autism spectrum conditions frequently have adverse experiences in accessing health care. An audit of experiences of families known to our tertiary service and hospital staff was conducted." The news correspondents obtained a quote from the research from Evelina Children's Hospital, "A checklist asking about particular aspects of behaviour and communication was developed and incorporated into pre-admission planning. Awareness of the child/young person's communication needs and behaviours, plus good preplanning by all staff involved and a team member allocated to ensure that the care plan is carried through, has resulted in a vastly improved 'patient experience' from the perspective of family and staff. Children and young people with autism spectrum disorder, often with coexisting learning difficulties, vary greatly in their reactions to hospital admission." According to the news reporters, the research concluded: "Preplanning that involves the family with a dedicated informed staff member can dramatically reduce distress and improve the patient and staff experience." For more information on this research see: Ensuring successful admission to hospital for young people with learning difficulties, autism and challenging behaviour: a continuous quality improvement and change management programme. Child, 2012;38(6):789-97. (Wiley-Blackwell - www.wiley.com/; Child onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-3588) Our news journalists report that additional information may be obtained by contacting K. Pratt, Guy's & St Thomas' NHS Foundation Trust Evelina Children's Hospital and King's College London, London, UK.

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Autism and Developmental Disorders; Researchers from State University of New York Discuss Findings in Autism and Developmental Disorders 367 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 210 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Fresh data on Autism and Developmental Disorders are presented in a new report. According to news originating from Cortland, New York, by NewsRx correspondents, research stated, "The purpose of the research was to conduct a quality indicator analysis of studies exploring the effects of antecedent exercise on self-stimulatory behaviors of individuals with autism spectrum disorders (ASD). Educational Resources Information Center (ERIC), Google Scholar, SPORTDiscus, PsychINFO, and PubMed/MedLine databases from 1980 to October 2010 and reference lists of included articles were searched." Our news journalists obtained a quote from the research from the State University of New York, "Twelve research studies employing group experimental (Gersten et al., 2005) or single-subject designs (Horner et al., 2005) met inclusion criteria. Each study was assessed for the presence and clarity of quality indicators. Group experimental and single-subject designs met 48% and 82% of quality indicators, respectively. This suggests that the effects of antecedent exercise on self-stimulatory behaviors of individuals with ASD is incomplete and claims of exercise being an evidence-based practice are premature. Several indicators were difficult to interpret or lacking clear definitions." According to the news editors, the research concluded: "Recommendations for clarifying and applying the quality indicators are offered." For more information on this research see: Evidence-based practice: Quality indicator analysis of antecedent exercise in autism spectrum disorders. Research in Autism Spectrum Disorders, 2012;6(4):1418-1425. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651)

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Autism; Researchers from Sun Yat-Sen University Report Recent Findings in Autism 325 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 211 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Investigators discuss new findings in Autism. According to news originating from Guangdong, People's Republic of China, by NewsRx correspondents, research stated, "Impaired cognitive flexibility in children with autism spectrum disorder (ASD) has been reported in previous literature. The present study explored ASD children's visual scanning patterns during the Dimensional Change Card Sorting (DCCS) task using eye-tracking technique." Our news journalists obtained a quote from the research from Sun Yat-Sen University, "ASD and typical developing (TD) children completed the standardized DCCS procedure on the computer while their eye movements were tracked. Behavioral results confirmed previous findings on ASD children's deficits in executive function. ASD children's visual scanning patterns also showed some specific underlying processes in the DCCS task compared to TD children. For example, ASD children looked shorter at the correct card in the postswitch phase and spent longer time at blank areas than TD children did. ASD children did not show a bias to the color dimension as TD children did." According to the news editors, the research concluded: "The correlations between the behavioral performance and eye moments were also discussed." For more information on this research see: Visual Scanning Patterns during the Dimensional Change Card Sorting Task in Children with Autism Spectrum Disorder. Autism Research and Treatment, 2012;2012():123053. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment www.hindawi.com/journals/aurt/)

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Autism and Developmental Disorders; Researchers' Work from Medical University Focuses on Autism and Developmental Disorders 343 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 214 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Investigators publish new report on Autism and Developmental Disorders. According to news reporting originating from Graz, Austria, by NewsRx correspondents, research stated, "We evaluated a program for teaching two adolescents with autism spectrum disorders (ASD) to perform more advanced operations on an iPod-based speech-generating device (SGD). The effects of the teaching program were evaluated in a multiprobe multiple baseline across participants design that included two intervention phases." Our news editors obtained a quote from the research from Medical University, "The first intervention focused on teaching the students to navigate between two screen pages and complete a multi-step response sequence to request preferred stimuli. The second intervention aimed to teach the students to turn on and unlock the device prior to navigating to the correct screen pages. Teaching procedures included response prompting, prompt fading, and differential reinforcement. Results showed that both interventions were effective in teaching the respective operations." According to the news editors, the research concluded: "Learning advanced operation of the iPod-based SGD could be seen as one way to promote greater independence in using such devices for multi-step communication." For more information on this research see: Teaching advanced operation of an iPod-based speechgenerating device to two students with autism spectrum disorders. Research in Autism Spectrum Disorders, 2012;6(4):1258-1264. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier www.elsevier.com; Research in Autism Spectrum Disorders www.elsevier.com/wps/product/cws_home/709651)

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Autism and Developmental Disorders; Scientists at Medical University of South Carolina Publish Research in Autism and Developmental Disorders 358 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 219 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Research findings on Autism and Developmental Disorders are discussed in a new report. According to news reporting out of Charleston, South Carolina, by NewsRx editors, research stated, "Children with Autism often show difficulties in adapting to change. Previous studies of cortisol, a neurobiologic stress hormone reflecting hypothalamic-pituitary-adrenal (HPA) axis activity, in children with autism have demonstrated variable results." Our news journalists obtained a quote from the research from the Medical University of South Carolina, "This study measured cortisol levels in children with and without Autism: (1) at rest; (2) in a novel environment; and (3) in response to a blood draw stressor. A significantly higher serum cortisol response was found in the group of children with autism. Analysis showed significantly higher peak cortisol levels and prolonged duration and recovery of cortisol elevation following the blood-stick stressor in children with autism." According to the news editors, the research concluded: "This study suggests increased reactivity of the HPA axis to stress and novel stimuli in children with autism." For more information on this research see: Enhanced cortisol response to stress in children in autism. Journal of Autism and Developmental Disorders, 2012;42(1):75-81. Journal of Autism and Developmental Disorders can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer www.springer.com; Journal of Autism and Developmental Disorders www.springerlink.com/content/0162-3257/)

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Autism and Developmental Disorders; Studies from K.L. Young and Co-Researchers in the Area of Autism and Developmental Disorders Published 416 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 230 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -Current study results on Autism and Developmental Disorders have been published. According to news originating from Winnipeg, Canada, by NewsRx correspondents, research stated, "The purpose of this research was to evaluate a self-instructional package (Fazzio & Martin, 2007) to train parents of children with autism to conduct discrete-trials teaching (DTT). In Study 1, we investigated the effectiveness of a self-instructional manual and a self-instructional video for teaching five parents of children with autism to correctly apply DTT to teach three tasks to a confederate who role-played a child with autism, and to their own child when possible." Our news journalists obtained a quote from the research, "Following an average of 4.76 h of training, the package produced a strong effect with three parents and a weak effect with two parents. In Study 2, we investigated the effectiveness of the self-instructional manual combined with role-playing and feedback, plus the self-instructional video, for teaching an additional five parents. Following an average of 4.68 h of training, all five parents demonstrated large, clinically significant gains in their performance of DTT, both with a confederate as well as with their own child, with a minimal investment of one-on-one instructor time." According to the news editors, the research concluded: "These results suggest that the training package in Study 2 has considerable potential as an effective, efficient and acceptable method of training parents of children with autism to apply DTT." For more information on this research see: Evaluation of a self-instructional package on discrete-trials teaching to parents of children with autism. Research in Autism Spectrum Disorders, 2012;6(4):13211330. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651)
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Autism; Studies from University of Tehran Describe New Findings in Autism 317 mots 29 octobre 2012 Mental Health Weekly Digest MHWK 238 Anglais Copyright 2012 Mental Health Weekly Digest via NewsRx.com 2012 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- A new study on Autism is now available. According to news reporting originating in Tehran, Iran, by NewsRx editors, the research stated, "The present study attempted to investigate the effect of perceptual-motor training on attention in children with autism spectrum disorders. The participants (20 girls and 20 boys) were divided into experimental and control groups." The news reporters obtained a quote from the research from the University of Tehran, "They were selected from among 85 subjects after primary tests to be matched. The design of the study was quasiexperimental including an independent variable, a pretest and a posttest. After considering the research hypotheses using descriptive statistics and one-way Analysis of Covariance (ANCOVA), the results suggested a significant difference in posttest scores of experimental and control groups after independent variable being applied." According to the news reporters, the research concluded: "The results also showed that perceptual-motor trainings for children with autism increase their attention because of the impact they have on increasing neurological and cognitive function." For more information on this research see: The effect of perceptual-motor training on attention in the children with autism spectrum disorders. Research in Autism Spectrum Disorders, 2012;6(4):1331-1336. Research in Autism Spectrum Disorders can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Research in Autism Spectrum Disorders - www.elsevier.com/wps/product/cws_home/709651) Our news correspondents report that additional information may be obtained by contacting J. Afshari, Univ Tehran, Tehran, Iran.

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