Pt: RAAGAS, NORWIN

PHARMACOLOGICAL SHEET

Drug name

General action

Specific action

indication

1. Cefuroxime 750mg IVTT q 8H

-Antibiotic -Cephalosporins (second generation)

-Bactericidal: inhibits synthesis of bacterial cell wall, causing cell death.

-lower respiratory infections caused by S. pneumoniae, S. aureus, E.coli, Klebsiela, H. influenzae, S. pyrogenes. -septicemia caused by S. pneumoniae, S. aureus, E.coli, Klebsiela, H. influenzae. -Perioperative prophylaxis.

contraindicatio n -allergy to cephalosporins or penicillins. -use cautiously with renal failure, lactation and pregnancy.

4. Metronidaz ole 500 g IVTT q 8H

-Antibiotic -Antibacterial -Amebicide -Antiprotozoal

-Bactericidal: Inhibits DNA synthesis in specifics anaerobes, causing cell death; antiprotozoaltrichomonacidal, amebicidal: biochemical mechanism of action in not known.

-preoperative, intraoperative, postoperative prophylaxis for patients undergoing colorectal surgery -Trichonomiasis -Acute intestinal amebiasis -prophylaxis for

-hypersensitivity to metronidazole; pregnancy -use cautiously with CNS disease, hepatic disease, candidiasis, blood dyscrasias, lactation.

Nursing responsibility CNS: headache, -check for liver dizziness, and renal lethargy, dysfunction, paresthesias lactation, GI: N&V, diarrhea, pregnancy, and anorexia, allergy to abdominal pain, medication flatulence, liver -sensitivity tets toxicity before and GU: nephrotoxicity during therapy if Hematologic: expected bone marrow response is not depression seen Local: pain, -have vitamin K abscess at available in case injection site, of hypoprophlebitis, inflation thrombinemia at IV site occurs -discontinue if hypersensitivity reactions occur. -teach pt to avoid alcohol while taking this drug, that the pt will experience these side effects: stomach upset or diarrhea. CNS: headache, dizziness, alaxia, vertigo, incoordination, insomnia, -assess for CNS seizures, fatigue or hepatic peripheral disease; neuropathy. candidiasis, GI: unpleasant blood dyscarias, metallic taste, pregnancy, anorexia, N&V, lactation.

Adverse effect

PT: DATIG, R

PHARMACOLOGICAL SHEET

Drug name

General action

Specific action

Indication

1. Cefuroxim e 750mg IVTT q 8H

-Antibiotic -Cephalosporins (second generation)

-Bactericidal: inhibits synthesis of bacterial cell wall, causing cell death.

-lower respiratory infections caused by S. pneumoniae, S. aureus, E.coli, Klebsiela, H. influenzae, S. pyrogenes. -septicemia caused by S. pneumoniae, S. aureus, E.coli, Klebsiela, H. influenzae. -Perioperative prophylaxis.

2. Ranitidine 50g IVTT q 8H

-Histamine2(H2) antagonist

-Competitively inhibits the action of histamine at the H2 receptors of the parietal cells of the stomach, inhibiting basal gastric acid secretion and gastric acid

-short-term treatment for active duodenal ulcer -short-term treatment of active, benign gastric ulcer -treatment of

Nursing responsibility -allergy to CNS: headache, -check for liver cephalosporins dizziness, and renal or penicillins. lethargy, dysfunction, -use cautiously paresthesias lactation, with renal failure, GI: N&V, pregnancy, and lactation and diarrhea, allergy to pregnancy anorexia, medication abdominal pain, -sensitivity tets flatulence, liver before and toxicity during therapy if GU: expected nephrotoxicity response is not Hematologic: seen bone marrow -have vitamin K depression available in case Local: pain, of hypoproabscess at thrombinemia injection site, occurs phlebitis, -discontinue if inflation at IV site hypersensitivity reactions occur. -teach pt to avoid alcohol while taking this drug, that the pt will experience these side effects: stomach upset or diarrhea. -allergy to ranitidine, lactation -use cautiously with impaired renal or hepatic function, CNS : headache, pregnancy. malaise, -assess for dizziness, allergy to drug, somnolence, impaired real or insomnia, vertigo hepatic function, CV : tachycardia, lactation,

contraindication

Adverse effect