2

Fig. 1 Experiment with recovery of originally extended RBC. Typical recovery time, tc =0.1 s (from Hochmuth R.M. et al., 1978)

Fig. 2 Recovery of neutrophils. A) cell is fully aspirated inside the pipette and it takes sausage-like shape, b) cell is expelled from the micropipette , and c)-e) cells recovers it spherical shape. Typical recovery time is about 50s. (From TranSon-Tay et al., 1991).

3 a) Fig. 3 A) Force applied to a fibroblast via magnetic bead, b) fibronactin coated magnetic beads bound to the cell membrane, and c) creep/relaxation response of the cell (from Bausch et al., 1998) b)

c)

Fig . 4 Hysteresis in cancer cells changes after cell treatment causing a re-arrangement of the cytoskeleton (from Suresh, 2007)

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