Topic 4.2-Meoisis (Core) Slide 1-title page Slide 2Meiosis- A reduction division of _________ to form haploid ___________.

Slide 3-6: Somatic cell nuclei (_______ cells) are diploid. They contain ________________ pair of each chromosome. During what phase do the chromosomes replicate in order to make pairs of sister chromatids, which join at the centromere? Meiosis is a process of how many divisions? What is reduction division? What separates sister chromatids? The end product of meiosis is from a ______ somatic diploid cell is _________ haploid gametes. Slide 7What does homologous mean? Where do they carry the same gene?

One of the homologous pair is ____. ______, meaning they are inherited from the father. ________ is inherited from the mother. _____ of the human chromosome pairs are homologous. The other pair are ____________________. Slide 8In preparation for the reduction division of meiosis, the chromosome ______________. When does the replication occur? Where is each single chromosome become paired as sister chromatids? Side 9-10: During what phase do the homologous chromosomes associate with each other? Crossing over between _____________ chromatids can take place.

This results in ____________________ of alleles and is a source of _______________ ___________ in gametes. Slide 11Explain what happens during Metaphase I.

Slide 12Spindle fibres contract during what phase? _________________ are separated and pulled to opposing poles. This is the ___________ _____________. Slide 13New nuclei form and the cytoplasm begins to divide by _________. Are the nuclei still diploid? Slide 14There is no ___________________ phase in Interphase II. Slide 15Explain what happens during Prophase II.

Slide 16Pairs of sister chromatids alight at the what? Spindle fibres and attach at the __________________.

Slide 17__________________ contract and centromeres are broken. The pairs of sister chromatids are pulled to opposing sides or same sides? Slide 18New ___________ ____________ are formed in telephase II. Slide 19-21: Fill in the chart below:

Slide 22-23: What happens in Meiosis I? Explain what you see.

Slide 24-30: Non-disjunction leads to changes in __________________ number. This can occur in anaphase I, anaphase II, or both?

Slide 31Fill in the blank:

Slide 32-33: Non-disjunction produces gametes with an ___________ number of chromosomes. What adds the homologous chromosomes? What does this result in?

Slide 34Non-disjunction in anaphase I or II leads to what? Explain how trisomy occurs.

Slide 35-36: Write down 3 facts from these slides: Slide 37-

What are the six steps for pre-natal test used to check for gender and trisomy disorders: 1. 2. 3. 4. 5. 6. Slide 38- Chorionic Villus Sampling or Amniocentesis. Slide 39What two things can risks of miscarriage? Slides 40-41: Explain how inheritance of chromosome 21 can lead to down syndrome (At least 3 things.. 3 marks). Slides 42-43: What gender is this karyotype? Slides 44-45: What gender is this karyotype? What is the trisomy? Slides 46-47: What gender is this karyotype? Slides 48-49: Is this a trisomy? If not, what is it? Slide 50-YAY YOURE DONE