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GMP Certified

A Natural Diabetic Medicine

Healing INDIA

CLINICALLY TESTED
The Combination of the most famous 9 herbal jewels of AYURVEDA comprises the active constituents of Sugar Remedy. Sugar Remedy is an ayurvedic diabetic medicine which significantly improves the BLOOD SUGAR LEVEL in type-2 diabetes patients in a natural way. Its unique combination of time tested AYURVEDIC herbal extracts and many years of CLINICAL RESEARCH makes Sugar Remedy the most efficient medicine for Type-2 diabetes.

Sugar Remedy is formulated to help Type-2 diabetic people in 4 ways:


a a a a Increases Insulin Production Improves Insulin Sensitivity & Reduces insulin Resistance of cells Maintain Blood Glucose level and Body weight Protects Kidney, Heart, Liver & Nervous system

Why Sugar Remedy?


a Clinically Researched product, in fact only Ayurvedic medicine which is manufactured in an ISO, GMP HACCP Kosher & Organic Certified facility. , , a Only Ayurvedic medicine specially prepared for type-2 Diabetes patients. a Unique combination of High-Quality Purified Ayurvedic Clinically Researched ingredients. a An Ayurvedic Diabetic medicine, gives no side effect. a As effective as standard diabetic allopathic medicine available in the market*. a Vegetarian CAPSULE form :Easy to use 2 capsule daily1 hr before meal. a In just 21 days brings significant improvement in Blood Sugar Level.
400 350 300 250 200 150 100 50 0 0th day 7th 14th day day 21st day 28th day
Diabetic control Sugar Remedy

*Rea tion d more in Research sec

9 Jewels of Ayurveda
BITTER MELLON (KARELA EXTRACT) - The key enzyme at the end of the digesting process is called alpha glucosidase and its job is to release glucose from the more complicated carbohydrates. Sugar Remedy reduces the efficiency of the carbohydrate breakdown and helps reduce the glucose absorption in the intestines. Bitter melon in Sugar Remedy plays a major role in the reduction of glucose absorption in the intestines and liver. WITHANIA (ASHWAGANDHA EXTRACT) - Stress always calls for Stress hormones {GH, Glucagone, Cortisol, etc}, their other name is Anti Insulin Hormones. They stop cells to take proper Glucose and Increase Blood glucose Level, make conditions very bad for diabetic patients. Withania in Sugar Remedy works on Nervous System and reduce the stress from the body. FENUGREEK (METHI EXTRACT ) - The seeds of fenugreek contain an amino acid called 4hydroxyisoleucine. This amino acid can stimulate the secretion of insulin from your pancreas. Also the Type-2 diabetics have a tendency to lose weight and hence our FENUGREEK EXTRACT in Sugar Remedy helps maintain their BMI. Because body weight has a major negative impact on the blood sugar levels, Sugar Remedy is formulated to help with weight management, too. SHILAJIT EXTRACT - Maintaining nerve health is important for anyone concerned about their blood sugar. Diabetic neuropathy is a common complication of diabetes, in which nerves are damaged as a result of high blood sugar level. Sugar Remedy contains Indian Ginseng (Ashwagandha) and Shilajit, potent antioxidant which helps to maintain nerve health in Type-2 diabetics.

TRIPHALA EXTRACT (AMLA, BAHEDA, HARDE) - Uncontrolled Blood Sugar Level and Intermediate Metabolites damage our Cellular Metabolic System. Ascorbic acid in Sugar Remedy acts as an antioxidant and rejuvenates cells. GYMNEMA SYLVESTRE EXTRACT(GUDMAR EXTRACT) - Gymnema is the Key ingredient acting as natural insulin. In Type-2 Diabetes our body cells become less sensitive to Insulin called Insulin Resistance. To cope with it, body needs Extra Insulin in blood. Gymnema in Sugar Remedy acts as Insulin as well as it reduces resistance to Insulin, so cells start taking proper Glucose from the blood, and blood glucose level goes down. EUGENIA JAMUN EXTRACT (JAMUN EXTRACT) - In Type-2 Diabetes cells become less sensitive to insulin. To have Normal Blood Glucose Level body needs more Concentration of Insulin. Eugenia in Sugar remedy helps Pancreatic Cells to grow and produce more Insulin. CINNAMON EXTRACT - Sugar Remedy contains cardio-protective and circulation-enhancing ingredients that work steadily to support your cardiovascular system. Cinnamon have the ability to lower blood glucose levels, it also lowered blood levels of fats and bad cholesterol, which are also to some degree controlled by insulin. VIJAYSAR (PTEROCARPUS MARSUPIUM) - Vijaysar/Bijasar or Indian kino regenerates beta cells of pancreas to produce insulin naturally and reduces cardinal symptoms for diabetes like Polyuria (Production of large volumes of urine), Polyphagia (Gluttonous excessive eating), Polydipsia (abnormally intense thirsts), burning pains in limbs and general weakness.

RESEARCH RESULTS SUMMARY


BLOOD GLUCOSE LEVEL BLOOD GLUCOSE LEVEL - Treatment with optimum dose of Sugar Remedy reduces fasting blood glucose level on 7th, 14th & 21st day as compared to the uncontrolled Blood Sugar Level on day 0. Optimum dose of Sugar Remedy reduces Fasting Blood Glucose level till normal desired level, but even high dose of Sugar Remedy does not produce Hypoglycemia [Low blood Sugar Level]. EFFECT ON LIVER - SGOT, SGPT are marker enzymes for liver; increase in blood level of these enzymes is a sign of liver damage. In the study it was found that treatment with sugar remedy significantly reduces blood SGOT, SGPT level in diabetic type-2 patients when compared to diabetic control. Results suggest that Sugar Remedy prevents liver damage in diabetes. EFFECT ON KIDNEY - Long-standing diabetes almost always destroys the kidney. SERUM Creatine and Uric Acid are good makers of Kidney Function. Treatment with Sugar Remedy significantly improves SERUM Creatine and Uric Acid Level. When compared to diabetic control, it reveals that Sugar Remedy effectively improves and preserves Kidney Function. EFFECT ON LIPID PROFILE - Obesity is the major problem among type-2 diabetes, in fact this is the one of the cause of the disease itself. Study provides evidences that treatment with Sugar Remedy reduces Blood cholesterol, triglycerides, LDL, VLDL and increases Blood HDL Level. CONCLUSION - Study Evidences Suggest that poly-herbal formulation of Sugar Remedy exhibits significant and consistent improvement of blood sugar level and hypolipidemic activity along with Improved Liver and Kidney functions.
400 350 300 250 200 150 100 50 0 0th day 7th 14th day day 21st day 28th day
Sugar Remedy Diabetic control

LIVER FUNCTION PARAMETER


SGOT SGPT

120 100 80 60 40 20 0 Diabetic control Std. Metformin SR-370


C C C b

KIDNEY FUNCTION PARAMETER


Creatine Uric Acid

12 10 8 6 4 2 0 Diabetic control Std. Metformin SR-370


C C C C

LIPID PROFILE
160 140 120 100 80 60 40 20 0 Diabetic control Std. Metformin SR-370
C C C bC b C b C C
Colestrol Triglyceride HDL VLDL LDL

SOURCE: Pre-Clinical Trials on Sugar Remedy - Jodhpur National University, Pharmacology Department.

Action Mechanism of Sugar Remedy


1) SUGAR REMEDY (SR) INCREASES INSULIN (I+) PRODUCTION IN PANCREATIC BETA CELLS
Pancreas Beta Cells Blood Circulation

I I

I I

2) SUGAR REMEDY (SR) INCREASES INSULIN (I+) SENSITIVITY IN LIVER MUSCLE CELLS SO THESE CELLS CAN ABSORB GLUCOSE (G+) FROM BLOOD PROPERLY AND REDUCE BLOOD GLUCOSE LEVEL

G GG

G GG
G

I X I

I I I

G
I

3) SUGAR REMEDY (SR) REDUCES GLUCOSE (G+) ABSORPTION IN SMALL INTESTINE VIA STOPPING GLUCOSE CUTTING ENZYMES

FAQ
What makes Sugar Remedy different from other Herbal Products? We guarantee that all standardized herbal extracts in Sugar Remedy have been laboratory tested to verify active ingredients. It is the only product in its segment that is clinically researched. How Sugar Remedy helps in Diabetes Type-2? It works as natural Insulin as well as increases growth of Pancreatic cells and improves sensitivity for Insulin in body cells.

Real Stories

Being a Doctor myself I have tried many Allopathic medicines, but they were causing Hypoglycemia. Thanks to SUGAR REMEDY my sugar level is normal now without any side effects. DR. SUSHMA TRIVEDI

It is a great product. My average fasting blood glucose before SUGAR REMEDY was 240. Now it's 113. That's amazing.. -MR. HEMARAMJI CHOUDRY - Excise Inspector

I came to know about Sugar Remedy from one of my disciples and it seemed trustworthy as it was made with totally natural herbs. Now my sugar level dropped to about 30 to 40 points SWAMI AMRATNAND JI MAHARAJ

With SUGAR REMEDY, proper diet, and exercise, my blood sugar is under 100 from the 140s and I have stopped my diabetic medication. Sowhatever the assurance I got while buying SUGAR REMEDY IS 100% CORRECT SHREEMATI. SANTOSH

What is the time period for Sugar Remedy to bring effect? In 21 days of medication Sugar Remedy shows significant improvement in Blood Glucose Level. How should I start taking Sugar Remedy? You should take 2 capsules with a glass of water 1 hour before lunch or dinner or follow prescriptions of your medical registered practitioner. Does Sugar Remedy have any side effects? It does not have any side effects as all ingredients are natural and clinically researched.

REFERENCES
Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation. - Nerurkar PV, Johns LM, Buesa LM, Kipyakwai G, Volper E, Sato R, Shah P Feher D, Williams PG, Nerurkar VR. , Bitter Gourd (Momordica charantia) is a Cornucopia of Health: A Review of its Credited Antidiabetic, Anti-HIV, and Antitumor Properties. - Fang EF, Ng TB.Curr Mol Med. 2011 Jul 1;11(5):417-36. Momordica charantia reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. Br J Nutr. 2008; Nerurkar PV, Lee YK, Motosue M, Adeli K, Nerurkar VR. Laboratory of Metabolic Disorders and Alternative Medicine, Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, Honolulu, HI, USA Gymnema's effects on glucose in human diabetics were first scientifically confirmed in 1926 when it was demonstrated that the leaves of Gymnema reduced urinary glucose. (K.G. Gharpurey, Indian Medical Gazette 1926; 61: 155). Al-Romaiyan A, Liu B, Asare-Anane H, Maity CR, Chatterjee SK, Koley N, Biswas T, Chatterji AK, Huang GC, Amiel SA, Persaud SJ, Jones PM. A novel Gymnema sylvestre extract stimulates insulin secretion from human islets in vivo and in vitro. Phytother Res. 2010 Sep;24(9):1370-6. Ahmed AB, Rao AS, Rao MV. In vitro callus and in vivo leaf extract of Gymnema sylvestre stimulate -cells regeneration and anti-diabetic activity in Wistar rats. Phytomedicine. 2010 Nov;17(13):1033-9. Epub 2010 Jul 27. Liu B, Asare-Anane H, Al-Romaiyan A, Huang G, Amiel SA, Jones PM, Persaud SJ. Characterization of the insulinotropic activity of an aqueous extract of Gymnema sylvestre in mouse beta-cells and human islets of Langerhans. Cell Physiol Biochem. 2009;23(1-3):125-32. Epub 2009 Feb 18. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol. 1990 Oct;30(3):295-300. Shanmugasundaram ER, Gopinath KL, Radha Shanmugasundaram K, Rajendran VM. Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharmacol. 1990 Oct;30(3):265-79. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol. 1990;30:281-294 Kirkham S, Akilen R, Sharma S, Tsiami A. The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance. Diabetes Obes Metab. 2009 Dec;11(12):1100-13. Crawford P Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a . randomized, controlled trial. J Am Board Fam Med. 2009 Sep-Oct;22(5):507-12. Roussel AM, Hininger I, Benaraba R, Ziegenfuss TN, Anderson RA. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr. 2009 Feb;28(1):16-21. Solomon TP Blannin AK. Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily , cinnamon ingestion in healthy humans. Eur J Appl Physiol. 2009 Apr;105(6):969-76. Dugoua JJ, Seely D, Perri D, Cooley K, Forelli T, Mills E, Koren G. From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark. Can J Physiol Pharmacol. 2007 Sep;85(9):837-47. Hlebowicz J, Darwiche G, Bjrgell O, Almr LO. Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects. Am J Clin Nutr. 2007 Jun;85(6):1552-6. Mang B, Wolters M, Schmitt B, Kelb K, Lichtinghagen R, Stichtenoth DO, Hahn A. Effects of a cinnamon extract on plasma glucose, HbA, and serum lipids in diabetes mellitus type 2. Eur J Clin Invest. 2006 May;36(5):340-4. Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care. 2003 Dec;26(12):3215-8. Malagasy Institute of Applied Research: Eugenia Jambolana -- Madagascar; Suzanne Urverg Ratsimamanga "In Vivo"; Hypoglycemic Activity of Eugenia Jambolana and Ficus Bengalensis: Mechanism of Action; S. Achrekar, et al.; 1991 "Indian Journal of Physiology and Pharmacology"; Antidiabetic and Antiulcer Effects of Extract of Eugenia Jambolana Seed in Mild Diabetic Rats; A. Chaturvedi, et al.; 2009 "Indian Journal of Physiology and Pharmacology"; Effect of Ethanolic Extract of Eugenia Jambolana Seeds on Gastric Ulceration and Secretion in Rats; A. Chaturvedi, et al.; 2007 "Indian Journal of Pharmacology"; Hepatoprotective Activity of Eugenia Jambolana Lam. in Carbon Tetrachloride Treated Rats; S.S. Sisodia and M. Bhatnagar; 2009 Bhattacharya, S.K.,AND A.V. Muruganandam. 2003. Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol. Biochem. Behav. 75:547-555. Achana, R., and A. Namasivyam. 1999. Antistressor effect of Withania somnifera. J. Ethnopharmacol. 64:91-93. Roy Upton. 2000.American Herbal Pharmacopoeia and Therapeutic compendium, Ashwagandha Root. Mirjalili,M.H., E.Moyano, M.Bonfill, R.M.Cusido and J.Palazon. 2009. Steroidal lactones from Withania somnifera, an ancient plant for novel medicine. Molecules. 14:2373-2393. Kapoor , L.D Handbook of Ayurvedic Medicinal plants; CRC Press: London, UK, 2001; pp. 337-338. Rastogi, R.P Mehrotra, B.N. Compendium of Indian Medicinal Plants; Central Drug Research .; Institute: New Delhi, India, 1998. Karnick CR.1991. A double-blind, placebo-controlled clinical study on the effecs of Withania somnifera and panax ginseng extracts on psychomotor performance in healthy Indian volunteers. Indian Med 3[2]:1-5. Journal of Ethnopharmacology: The Spermatogenic andOvogenic Effects of Chronically Administered Shilajit to Rats Indian Journal of Pharmacology: Effect of Shilajit on Blood Glucose and Lipid Profile

All the information given in the Brochure are based on Pre-Clinical, Clinical Trials. Effects of the medicine can vary from person to person.

UMALAXMI ORGANICS
Umalaxmi is an advanced bioceutical company with Indias largest manufacturing facility for specialty ingredients for the nutraceutical, food and beverage, sports nutrition and pet care industries. For us at Umalaxmi, Business is not an activity but the religion. Giving good services to customer is a business mantra for the company. * * * * * * * * Premium ingredients ISO, GMP HACCP KOSHER, ORGANIC & JAS Certified manufacturing plant , , Technical expertise to develop custom formulation Competitive edge due to in house raw material sourcing State of the art quality control Value-added customer services On-time delivery Responsible partners

Umalaxmi Organics Pvt. Ltd.


(A Govt. Recognized Export House) ISO 9001-2008, GMP, HACCP, KOSHER, ORGANICS Certified Company BRANCH OFFICE: 37-A, Bhagat Vatika, Rajbhawan Road, Civil lines, Jaipur, Rajasthan, INDIA. Tel. : +91 141 2222861, Fax : +91 141 2222761 Web. : www.sugarremedy.com Customer Care : Info@sugarremedy.com

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