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Medical Microbiology and Infection at a Glance STEPHEN H. GILLESPIE MD.FRCP (Edin), FRCPath Professor of Medical Microbiology Royal Free and University College Medical School (Royal Free C University ¢ London KATHLEEN B. BAMFORD MD,FRCPath, Senior Lecturer in Medical Microbiology Imper School of Medicine pital London Edited by JANET P.GILLESPIE MB, MRCGP General Practitioner ©2000 Blackwell Science Lid Exltorial tices: (Osney Mead, Oxford OX20EL 25 on Sect, London WIN 2B. 23 Ainslie Place. Edinburgh EH3 6A) 330 Main Street Malden MA (21485018, USA, 54 University Steet, Carton ‘Vieworia 3083, Australia 10,rue Casiniar Delavigne "7S006 Pars France ther Editorial Offices Black ll Wisenschafs- Verlag GmbH Kurfurstendamm 37 10707 Berlin, Germany Blackwell Science KK MG Kodenmacho Building 7-10 Kodenmacho Nibombashi ‘Chuo-ku, Tokyo 108 Japan Towa State University Press AA Blackwell Science Company 2121'S, State Avenue ‘Ames, Jowa 800148300, USA First published 2000 Reprinted 2000, 200 Setby Excel Typesetters Ca, Hong Kone Printed and bound in Groat Britain at the Alden Press, Oxford and Northampton The Blackwell Science logoisa teade mark of Blackyvll Science Ld, registered atthe United Kingdom Trade Marks Registry The right ofthe Autorstobe bistarnvrors iMesh Ao hs Work eae has been asrted in acordance ea esd with the Copyright, Designs and Abingdon, Oxon OX144YN Pateats Ac (one Teens 50 an uiasasss) llrightsreserved. No part of {hs publicotion may be eprntuccd The Americas Stored ina ettval sssem, or lacksell Pulshine Iransmited,inany form ory any cio AIDC ‘means electronic mechanical PO Box 20 ‘Photocopvine recording or otherwise, 50 Winter Sport Lane Exceptanpermited by the UK Wiiaton 1 05498 020 Gopyright-Designs and Patents Act. (Onder Te: SOD 216 2522 Tons without the pao pe Fax: M2 864 7626) ofthe copyright one. nil ‘Blackwell Seienee Ply Lid catalogue record fo this tite StUnivenaity Street isavalabl from the Brish Library Carton, Vitoria 3083 (Onder Te 398570300 ISBN 0.632-050268 Fax: 39875001) Library of Congress Cataloging-in-publication Data Peete eee [Blackwell Sience visit our website: Gittespic, SH. ‘www lackwellsecnec.com ‘Medical microbiology and infection ataglance/ Stephen H. Gillespie, Kathleen B. Barntord Eeited by Janet PCillspi P Includes index ISBN 0.632.050268 1. Medical microbiology. 1 Bamford, Kathloen i, Tie [DNLME 1. Microbiology. 2, Communicable Diseases. 616-01—de2t DNLM/DLC for Library of Congress we.2684 cP. Contents 10 u 2 B 4 15 16 ” 18 19 20 2 2 B Py 25 26 ” Preface,7 Concepts, Structure and classification of bacteria, 8 Innate immunity and normal flora, 10 Pathogenicity and transmission of ‘microorganisms, 12 ‘The laboratory investigation of infection, 14 Antibacterial therapy, 16 Resistance to antibacterial agents. 18 Hospital-acquired infections, 20 Control of infection in hospital, 22 Control of infection in the community, 24 Bacteriology Staphylococcus, 26 Streptococcal infections, 28 Corynebacterium, Listeria and Bacillus,30 ‘Mycobacteria, 32 Clostridium species, 34 ‘Non-sporing anaerobic infections,36 Neisseria and Haemophilus,38 ‘Small Gram-negative cocco-bacilli: Bordetella, Brucella, Francisella and Yersinia, 40 Enteric Gram-negative bacteria, 42 Vibrio, Campylobacter and Helicobacter, 44 Environmental pathogens: Pseudomonas Burkholderia and Legionella, 46 Chlamydia, Mycoplasma and Rickettsia, 48 Spiral bacteria, 50 Virology Virus structure, classification and antiviral therapy,52 Herpesvirus 1,54 Herpesvirus 11,56 DNA viruses: adenovirus, parvovirus and, poxvirus,58 Measles, mumps and rubella, 60 28 29 30 31 32 3B 50 Influenza and parainfluenza viruses, 62 Enterovirus and viruses infecting the gastrointestinal tract, 64 Hepatitis viruses, 66 ‘Tropical, exotic or arbovirus infections, 68 Mycology Yeast infections, 70 Filamentous fungi, 72 Parasitology Intestinal protozoa,74 Malaria, leishmaniasis and trypanosomiasis, 76 Gut helminths, 78. Tissue helminths, 80 Systemic infection Congenital and perinatal infections, 82 HIV infection and AIDS,84 Pyrexia of unknown origin and septicaemia, 86 Endocarditis, myocarditis and pericarditis, 8 Infections of the central nervous system, 90 Respiratory tract infections, 92 Urinary and genital infections, 94 Infections of the bones and joints, 96 Bacterial diarrhoeal disease, 98. Zoonoses, 100 Infections in immunocompromised patients, 102 Ocular infections, 104 Infections of the skin and soft tissue, 106 Glossary, 109 Antibiotic table, 113 Index, 117 A colour plate section follows facing page 120

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