Académique Documents
Professionnel Documents
Culture Documents
What is it?
Technically speaking, an affinity group of the Informatics Key Function Committee of the CTSA Consortium
A group of people interested in pursuing answers to the question how can ontologies best enable translational science?
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History
October 2010
Hogan and Scheuermann hatch idea at dinner during IKFC meeting
Spring 2011
Initial proposal takes shape, distributed to folks for feedback
History (continued)
April 2012
First Clinical and Translational Science Ontology Workshop held in Baltimore, MD Participants enthusiastic about forming ontologyrelated AG in IKFC Given takeover of CTSA Consortium support by C4, old AG proposal forms no longer in use Proposal split into elevator pitch and operations documents
July 2012
Elevator pitch and operations documents submitted to IKFC Operations Committee
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History (continued)
November 2012
C4 and IKFC Operations Committee member inform Hogan that the Clinical and Translational Science Ontology Affinity Group (CTSO-AG) is approved!
December 2012
C4 sets up infrastructure for CTSO-AG on ctsacentral.org CTSO-AG keeps Google Group for inclusion of members outside Consortium
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History (continued)
January 2013
First CTSO-AG monthly call held
February 2013
Second Clinical and Translational Science Ontology Workshop held in Orlando, Florida (sponsored by Translational Research Institute of UAMS and cosponsored by NCBO)
March 2013
Second CTSO-AG call held
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Current Activities
Defining subject matter of the AG
Ontology in support of CTSA evaluation Identifying and cataloging projects, software, research studies, etc. that use ontologies and the ontologies they employ Generating a tutorial on ontology targeted at junior translational science investigators
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Definition Activity
Are we interested in any type of controlled vocabulary, thesaurus, taxonomy, classification, etc.? If not, what are the distinctions and why do they matter? White paper is currently on v6 and very close to distribution to entire CTSO-AG Lead: Mathias Brochhausen
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Evaluation Activity
Collaboration with evaluation KFC Representing key metrics for interoperability of evaluation data Has links to CTSAConnect project to deliver investigator data (e.g., grants, pubs) data into the process Two-page proposal distributed for feedback, with ultimate goal of obtaining buy in from leadership of Evaluation KFC Lead: Dagobert Soergel
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Catalog Activity
If we are going to understand how ontologies enable translational science, then we need to track their use and associated outcomes Setting up Wiki site Made initial decisions for organization of site Lead: William Hogan
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Tutorial Activity
Initial goal is deck of ~60 PowerPoint slides Currently collecting folks existing tutorials, slides, videos, Wikis, etc. Leads: He, Brochhausen, Soergel, Hogan
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C4 site
https://ctsacentral.org/committee/ikfc-clinical-and-translationalscience-affinity-group-ctso-ag list.kfc.informatics.ontology@ctsacentral.org
CTSO Workshops
First: http://www.bioontology.org/wiki/index.php/Clinical_and_Trans lational_Science_Ontology_Workshop Second: http://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Worksh op
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Join monthly calls (details emailed to both Google Group and C4 listservs)
Second Tuesday of the month at 2p ET Next one is Tuesday, April 9 at 2p ET
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Acknowledgements
Those instrumental to formation of group:
Richard Scheuermann Barry Smith Warren Kibbe Lindsay Cowell Melissa Haendel Jesse Tennenbaum Mathias Brochhausen Dagobert Soergel JENNIFER BUFFORD! And the remainder of the 37 participants of the first Workshop who self-identified as being interested in participating
IKFC Operations Committee for their valuable criticisms, suggestions, recommendations, etc. Award UL1TR000039 from NCATS
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