NAME

CLASSIFICATION

Dosage & Route

ACTION

INDICATION

ADVERSE EFFECT
body as a Whole: Hypersensitivity [Pruritus, rash, urticaria, edema, hemorrhagic urticaria (rare), anaphylactoid reaction (rare)], sweating, skeletal muscle flaccidity; cold, clammy skin, hypothermia. CNS: Euphoria, insomnia, disorientation, visual disturbances, dysphoria, paradoxic CNS stimulation (restlessness, tremor, delirium, insomnia),

CONTRAINDICATION

NURSING CONSIDERATION
Assess lung sounds, PR and BP before drug administration and during peak of medication. Observe fore paradoxical spasm and withhold medication and notify physician if condition occurs. Administer PO medications with meals to minimize gastric irritation. Extended-release tablet should be swallowed-whole. It should not be crushed or chewed. If administering medication through inhalation, allow at least 1 minute between inhalation of aerosol medication. Advise the patient to rinse mouth with

MORPHINE SULFATE (morfeen) Brand Names: Astramorph PF, Avinza, DepoDur, Duramorph, Epimorph , Kadian, MSIR, MS Contin, Oramorph SR, Roxanol, RMS, Statex

Availability

central nervous system (cns) agent; analgesic; narcotic (opiate) agonist)

morphine hydrochloride Rectal suppositories: 20 mg, 30 mg Syrup: 1 mg/ml, 5 mg/ml, 10 mg/ml, 20 mg/ml, 50 mg/ml Tablets: 10 mg, 20 mg, 40 mg, 60 mg

Natural opium alkaloid with agonist activity by binding with the same receptors as endogenous opioid peptides. Narcotic agonist effects are identified with 3 types of receptors: Analgesia at supraspinal level, euphoria, respiratory depression and physical dependence; analgesia at spinal level, sedation and miosis; and

Symptomatic relief of severe acute and chronic pain after nonnarcotic analgesics have failed and as preanesthetic medication; also used to relieve dyspnea of acute left ventricular failure and pulmonary edema and pain of MI.

Hypersensitivity to opiates; increased intracranial pressure; convulsive disorders; acute alcoholism; acute bronchial asthma, chronic pulmonary diseases, severe respiratory depression; chemicalirritant induced pulmonary edema; prostatic hypertrophy; diarrhea caused by poisoning until the toxic material has been eliminated; undiagnosed acute abdominal conditions; following biliary tract surgery and surgical anastomosis; pancreatitis; acute ulcerative colitis; severe liver or renal insufficiency; Addisons disease;

dysphoric, hallucinogenic and cardiac stimulant effects.

convulsions (infants and children); decreased cough reflex, drowsiness, dizziness, deep sleep, coma, continuous intrathecal infusion may cause granulomas leading to paralysis. Special Senses: Miosis. CV: Bradycardia, palpitations, syncope; flushing of face, neck, and upper thorax; orthostatic hypotension, cardiac arrest. GI: Constipation, anorexia, dry

hypothyroidism; during labor for delivery of a premature infant, in premature infants; pregnancy (category B; D in long-term use or when high dose is used); lactation.

water after each inhalation to minimize dry mouth. Inform the patient that Albuterol may cause an unusual or bad taste.

mouth, biliary colic, nausea, vomiting, elevated transaminase levels. Urogenital: Urinary retention or urgency, dysuria, oliguria, reduced libido or potency (prolonged use). Other: Prolonged labor and respiratory depression of newborn. Hematologic: Precipitation of porphyria.