BBT genetics What is it about the structure of DNA that allows it to be faithfully replicated?

DNA Is replicated through semi conservative replication. This means that the DNA strands are unwound and each individual strand is used as a template to make a complementary strand from it. The DNA base adenine is complementary in structure and forms two Hydrogen bonds with the thymine base while cytosine forms 3 hydrogen bonds with guanine. This complementarity base pairing between DNA bases ensures that DNA is replicated accurately from the parent strand DNA is replicated faithfully due to complementary base pairing but sometimes replication errors occurs whereby a wrong base pair is placed that is not complementary to the template strand. Correction of the mismatch from replication is possible due to the complementarity of the template strand to the coding strand. When correcting the mismatch created the repair mechanism recognizes the template strand because it has been methylated beforehand. Proteins then mark the mismatch for repair. If the mismatch is on the 5 area then the unmethylated strand is unwound and degraded from the 3 to 5 direction. Repair from the 3 side of the cleavage site is done in a similar way. The removed segments from the unmethylated strand are then replaced by DNA polymerase III and DNA ligase. What is it about DNA that allows its genetic materials to be passed on from one generation to the next?

DNA is able to pass on its genetic materials from one generation to the next due to it complementary binding of its base pairs in the two DNA strands. DNA is passed on to the next generation the production of germ cells which then combine by fertilization to form a diploid cell. This then has to undergoes repeated replication in new cells in order for the embryo to develop. DNA replication is very accurate and this allows genetic materials to be passed on from one generation to the next. The DNA can replicate faithfully by semi conservative replication whereby SSB proteins and helicases are used to unwind and stabilize two DNA strands which have formed a replication fork. The replication fork is asymmetrical due to the anti-parallel direction of the DNA strands. Polymerase III can only replicate from the 5 to 3 direction. The leading strand only needs the RNA primer to bind allowing DNA polymerase to III to build the second strand continuously through complementary base pairing. The lagging strand it goes in the 3 to 5 direction so the process is instead carried out by in small pieces of DNA strand called Okazaki fragments. The Okazaki fragments are then spliced together using an enzyme called DNA ligase.