CURRICULUM VITAE

OF

MARUF AHMED
MAILING ADDRESS: Associate Professor Department of Pharmacy University of Rajshahi Rajshahi-6205, BANGLADESH. Tel: +880-721-750041-54/4110 (Off) +880-721-750041-54/3081 (Res.) +880-721-751067 (Res.) Mobile: +88-01556309775, +88-01718442311 Fax: +880-721-750064 E-mail: amaruf2000@yahoo.com amaruf08@bttb.net.bd

EDUCATIONAL QUALIFICATION: 2005 Doctor of Philosophy (PhD.), Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan 1991 Master of Pharmacy (M.Pharm.), University of Dhaka, Dhaka-1000, Bangladesh, First Class (Examination held in 1994)*, Marks obtained- 373 (62.2%) 1990 Bachelor of Pharmacy (B.Pharm.Honours), University of Dhaka, Dhaka-1000, Bangladesh, First Class (Examination held in 1992)*, Marks obtained- 1016 (63.5%) 1987 Higher Secondary Certificate (H.S.C.) Comilla Board, Bangladesh, First Division, Marks obtained-832 (83.2%) 1985 Secondary School Certificate (S.S.C.) Comilla Board, Bangladesh, First Division, Marks obtained- 744 (74.4%) * Due to session jam PRESENT STATUS: Working as an Associate Professor in the Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh since July 16, 2005. JOB EXPERIENCE: From Sept. 30, 1999 to July 15, 2005 From Sept. 30, 1996 to Sept. 29, 1999 From June 15, 1995 to Sept. 24,1996 Worked as Assistant Professor in the Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. Worked as Lecturer in the Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. Worked as Quality Assurance Officer in the Department of Quality Control, Ciba-Geigy (Bangladesh) Ltd.

RESEARCH EXPERIENCE: About two-year research experience on Pharmaceutics carried out in the Department of Pharmacy, University of Dhaka, Bangladesh. In this period I carried out Suppository Preparation, Dissolution, Spectroscopic Assay and Thin Layer Chromatography for the determination of degradation. Four year research experience on Molecular Pharmacology carried out in the Department of Pharmacology, Niigata University of Pharmacy and Applied Life Sciences. I also have basic Computer Literacy.

TRAINING OBTAINED: 1) Three weeks in-plant training in Fisons (Bangladesh) Ltd. In this time I observed manufacturing as well as quality control operation of tablets, capsules, injectable (both antibiotic and non-antibiotic), ointment, toiletries and liquid preparations. 2) Three days Pharmaceutical Marketing Training organized by Pharmacy Graduates Association, Bangladesh. 3) Ten weeks Computer Training on MS-Excel organized by Rajshahi University Computer Center. SCHOLARSHIPS/AWARDS: 1) Comilla Board scholarship at SSC and HSC level. 2) Dhaka University scholarship at graduate level. 3) Dean's Award at graduate level. MEMBER OF PROFESSIONAL ORGANISATION: 1) General member, Bangladesh Pharmaceutical Society. 2) General member, Pharmacy Graduates Association, Bangladesh. 3) General member, Rajshahi University Teachers Association. PERSONAL INFORMATION: Father's name : Late A.K.M. Abdul Mannan Permanent Address : C/O- Dr. Jasimuddin Ahmed Holding No. 813, Station Road, Sirajganj, Post Code- 6700, Bangladesh Date of birth : November 11, 1969 Age : 39 years Nationality : Bangladeshi by birth Marital Status : Married Religion : Islam Sex : Male LIST OF PUBLICATIONS: 1. A dissertation on "Release Kinetics Studies of Diclofenac Sodium from Sustained Release Suppositories" was submitted to the Department of Pharmacy, University of Dhaka as a partial fulfillment for the degree of Master of Pharmacy. 2. M. Ahmed, R. Jalil, M.A. Islam and S.M. Shaheen, Release Kinetics of Diclofenac Sodium from preparatory Glycerol Monostearate Suppositories, Rajshahi University Studies, Part-B, 26; 27-33, 1998 3. M.A.H.M. Kamal, M.A. Islam, M. Rashid and M. Ahmed, Formulation of sustained release Indomethacin suppositories, Journal of Bio-Science, 6; 141-148, 1998 4. M.A.H.M. Kamal, M. Rashid, M. Ahmed, M.H.U. Biswas and M.A. Islam, Release Kinetics of indomethacin from HPMC based sustained release matrix: effects of bees wax and stearic acid, Nuclear Science and Applications, 8 (1-2); 105-108, 1999 5. M.A. Bakr, M.A.W. Sarker, M.A. Islam and M. Ahmed, Malic acid-propane 1,2 diol copolyester as an enteric coating material, Journal of Polymer Materials, 17(4); 467471, 2000 6. M. Ahmed, R. Jalil, M.A. Islam and S.M. Shaheen, Preparation and Stability Study of Diclofenac Sodium, Pakistan Journal of Biological Sciences , 3(10); 17551757,2000. Link to article: http://ansijournals.com/pjbs/2000/1755-1757.pdf 7. M.S Amran, M. Ahmed, M.A. Gafur and M.A. Islam, In vitro Dissolution of commercial Paracetamol tablets, Journal of Asiatic Society, 26(2); 285-288, 2000 8. M. Helal Uddin Biswas, A.R.M. Ruhul Amin, M. Shah Alam Bhuiyan, M.A. Rashid, M. Ahmed and M.A. Islam, In vitro antibacterial screening of the metabolite of a

Monocillium species isolated from a soil sample of Bangladesh, The Sciences, 1 (1); 25-27, 2001 9. Maruf Ahmed, M. Helal Uddin Biswas, M. Motiur Rahman, M. Shah Alam Bhuiyan, M.Abu Hena Mostofa Kamal and Golam Sadik, Development of a spectrophotometric method for the determination of aspirin in blood sample, The Sciences, 1 (2); 61-62, 2001 10. Takafumi Nagatomo, Toshio Ohnuki, Masaji Ishiguro, Maruf Ahmed and Takashi Nakamura, -Adrenoceptors: Three-Dimensional Structures and Binding Sites for Ligands, Japanese Journal of Pharmacology , 87; 7-13, 2001. Link to article: 11. Yoko Hanaoka, Takashi Nakamura, Maruf Ahmed, Hitoshi Kurose, Taku Nagao and Takafumi Nagatomo, Binding studies of -adrenoceptor agonists and antagonists in COS-7 cells expressing human 3- adrenoceptors by Radioligand Binding Assay, Pharmacology Reviews and Communications , 11(4); 285-290, 2001. Link to abstract: 12. M.A. Bakr, M. Ahmed, M.A. Islam, M.R. Karim and M.H.U. Biswas, Toxicological study of malic acid-propane 1,2 diol-glycerol copolyesters on brine shrimp Nauplii, The Sciences, 2 (1); 32-34, 2002 13. Masaji Ishiguro, Yukiyo Futabayashi, Toshio Ohnuki, Maruf Ahmed, Ikunobu Muramatsu, Takafumi Nagatomo, Identification of binding sites of prazosin, tamsulosin and KMD-3213 with 1-adrenergic receptor subtypes by molecular modeling, Life Sciences, 71(21); 2531-2541, 2002. Link to abstract: http://dx.doi.org/10.1016/S0024-3205(02)02077-5 14. Maruf Ahmed, Yoko Hanaoka and Takafumi Nagatomo. Structure-activity relationship studies of phenoxypropanolamine derivatives for 3-adrenergic activity. Nippon Yakurigaku Zasshi, 120(1):112P-113P, 2002 . Link to abstract: 15. Maruf Ahmed, Yoko Hanaoka, Takafumi Nagatomo, Tatsuya Kiso, Takao Kakita, Hitoshi Kurose, and Taku Nagao, Binding and functional affinity of some newly synthesized phenethylamine and phenoxypropanolamine derivatives for their agonistic activity at recombinant human 3- adrenoceptor, Journal of Pharmacy and Pharmacology, 55; 95-101, 2003. Link to abstract: http://dx.doi.org/10.1211/002235702531 16. Takashi Nakamura, Maruf Ahmed, Jun Suzuki, Kimiyoshi Kaneko, Hajime Katayama and Takafumi Nagatomo, Molecular pharmacology of -adrenoceptor antagonists, y Yakuri, 66(3/4):141-149, 2004 17. Maruf Ahmed, Yoko Hanaoka, Tatsuya Kiso, Takao Kakita, Yoshikazu Ohtsubo and Takafumi Nagatomo. Molecular characterization of pharmacological properties and selectivity of SWR-0315NA for 3-adrenoceptors. Biological and Pharmaceutical Bulletin, 27(5):718-722, 2004. Link to article: 18. Maruf Ahmed, Yoko Hanaoka, Tatsuya Kiso, Takao Kakita, Yoshikazu Ohtsubo, Ikunobu Muramatsu and Takafumi Nagatomo, Comparison of the binding affinity of some newly synthesized phenylethanolamine and phenoxypropanolamine compounds at recombinant human - and 1-adrenoceptor subtypes, Journal of Pharmacy and Pharmacology, 57: 75-81, 2005. Link to abstract: http://dx.doi.org/10.1211/0022357055074 19. A dissertation on Pharmacological and Molecular Characterization of Novel SWRcompounds for -adrenergic receptors as assessed by Molecular Modeling, SiteDirected Mutagenesis, Binding Affinity and Functional Activity was submitted to the Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, in partial fulfillment of the requirements for the degree of Doctor of Philosophy (PhD) in Pharmacology 20. M. Belal Hossain, M. Rashid, M. Ahmed, S. M. Shaheen and A. K. M. Motahar Hossain, Release kinetics studies of Ibuprofen from sustained release

microcapsules, Dhaka University Journal of Pharmaceutical Sciences , 4: 45-49, 2005. Link to article: http://www.pharmadu.net/journal2005/?art=109 21. Sharif Mohammad Shaheen, Abdul Khalek Molla, Maruf Ahmed and A. K. M. Motahar Hossain, Application of a few waxy materials on the release of Naproxan from polyethylene glycol based suppositories, Pakistan Journal of Biological Sciences, 8(12): 1585-1689, 2005. Link to article: http://ansijournals.com/pjbs/2005/1685-1689.pdf 22. Maruf Ahmed, Masaji Ishiguro and Takafumi Nagatomo, Molecular modeling of SWR-0342SA, a 3-selective agonist, with 1- and 3-adrenoceptor, Life Sciences, 78(17): 2019-2023, 2006. Link to abstract: http://dx.doi.org/10.1016/j.lfs.2005.09.023 23. Sharif Mohammad Shaheen, Fazle Rabbi Shakil Ahmed, Md. Nazir Hossen, Maruf Ahmed, Md. Shah Amran and Md. Anwar-Ul-Islam, Liposome as a carrier for advanced drug delivery, Pakistan Journal of Biological Sciences , 9(6): 1181-1191, 2006. Link to article: http://ansijournals.com/pjbs/2006/1181-1191.pdf 24. Habib Abul Muntasir, Jyuniti Takahashi, Mamunur Rashid, Maruf Ahmed, Tadazumi Komiyama, Murad Hossain, Jun Kawakami, Masayuki Nashimoto, and Takafumi Nagatomo, Site-directed mutagenesis of the serotonin 5-hydroxytryptamine2C receptor: identification of amino acids responsible for Sarpogrelate binding, Biological and Pharmaceutical Bulletin, 29(8): 1645-1650, 2006. Link to article: http://bpb.pharm.or.jp/bpb/200608/b08_1645.pdf 25. Sharif Mohammad Shaheen, Md. Nazir Hossen, Maruf Ahmed and Md. Shah Amran, Green Tea in Health Care: A Natural Medicine, A Natural Drink, Journal of Applied Science Research 2(6): 306-309, 2006. Link to article: http://www.insinet.net/jasr/2006/306-309.pdf 26. Sharif Mohammad Shaheen, Md. Nazir Hossen, Kazi Mehedul Islam, Maruf Ahmed, Md. Shah Amran and Mamunur Rashid, Effect of Bio-adhesive Polymers like HPMC, Gelatin, Na-CMC and Xanthan Gum on Theophylline Release from Respective Tablets, International Journal of Pharmacology 2(5): 504-508, 2006. Link to article: http://ansijournals.com/ijp/2006/504-508.pdf 27. Maruf Ahmed, Habib Abul Muntasir, Murad Hossain, Masaji Ishiguro, Tadazumi Komiyama, Ikunobu Muramatsu, Hitoshi Kurose, and Takafumi Nagatomo, Betablockers show inverse agonism to a novel constitutively active mutant of 1adrenoceptor, Journal of Pharmacological Science, 102: 167172, 2006. Link to article: http://www.jstage.jst.go.jp/article/jphs/102/2/167/_pdf 28. Maruf Ahmed, Habib Abul Muntasir, Masaji Ishiguro, Tadazumi Komiyama, Ikunobu Muramatsu, Murad Hossain, Takashi Nakamura, Takafumi Nagatomo, Pharmacological and molecular characterization of novel SWR-compounds for adrenergic receptors as assessed by molecular modeling, site-directed mutagenesis, binding affinity and functional activity, y Yakuri /Pharmacometrices, 71(1/2): 110, 2006. 29. Most. Afia Akhtar, Mamunur Rashid, Mir Imam Ibne Wahed, Md. Robiul Islam, Sharif Mohammad Shaheen, Md. Ariful Islam, Md. Shah Amran and Maruf Ahmed, Comparison of long-term antihyperglycemic and hypolipidemic effects between Coccinia cordifolia (Linn.) and Catharanthus roseus (Linn.) in alloxan-induced diabetic rats, Research Journal of Medicine and Medical Sciences , 2(1): 29-34, 2007. Link to article: http://insinet.net/rjmms/2007/29-34.pdf 30. Kaori Miyajima, Mikio Nakazawa, Habib Abul Muntasir, Murad Hossain, Maruf Ahmed and Takafumi Nagatomo, Differential inhibition by oxygen radicals of vasoactive amines-induced contractions in the porcine coronary artery, Biological and Pharmaceutical Bulletin, 30(7): 1242-1245, 2007. Link to article: http://www.jstage.jst.go.jp/article/bpb/30/7/1242/_pdf

31. Ranjan Kumar Barman, M. Anwar Ul Islam, Maruf Ahmed, Mir Imam Ibne Wahed, Robiul Islam, Alam Khan, M. Belal Hossain and Bytul M Rahman, Simultaneous high-performance liquid chromatographic determination of atenolol and amlodipine in pharmaceutical-dosage form, Pakistan Journal of Pharmaceutical Sciences , 20(4): 274-279, 2007. Link to abstract: http://www.pakmedinet.com/11124 32. Md. Shah Amran, Maruf Ahmed, SM Shaheen, Sheikh Niaz Morshed, Md. Jahangir Alam Khandakar, Md. Masudur Rahman, Md. Mosiur Rahman and Md. Amjad Hossain, A study on the packaging information of essential drug products used at union and thana health complex level in Bangladesh, Pakistan Journal of Pharmaceutical Sciences, 20(4): 327-332, 2007. Link to abstract: http://www.pakmedinet.com/11134 33. Kazuya Takahashi, Murad Hossain, Maruf Ahmed, Mohiuddin Ahmed Bhuiyan, Toshio Ohnuki and Takafumi Nagatomo, Asp125 and Thr130 in transmembrane domain 3 are major sites of 1b-adrenergic receptor antagonist binding, Biological and Pharmaceutical Bulletin, 30(10): 1891-1894, 2007. Link to article: http://bpb.pharm.or.jp/bpb/200710/b10_1891.pdf 34. Bytul M. Rahman, M. Mukhlesur Rahman, Maruf Ahmed, Mir Imam Ibne Wahed, Ranjan Kr Barman, M. Abdur Rashid Khan, M. Belal Hossain and Robiul Islam, Development and evaluate the formulation of Ketorolac Tromethamine tablets and a comparative study with marketed product, Research Journal of Medicine and Medical Sciences, 2(2): 102-105, 2007. Link to article: http://www.insinet.net/rjmms/2007/102-105.pdf 35. Bytul M. Rahman, M. Mukhlesur Rahman, Maruf Ahmed, M. Robiul Islam, Mir Imam Ibne Wahed, Ranjan Kr Barman, M. Abdur Rashid Khan, M. Belal Hossain and Md. Shah Amran. Simultaneous high-performance liquid chromatographic determination of metformin hydrochloride and rosiglitazone maleate in pharmaceutical-dosage form, Research Journal of Medicine and Medical Sciences , 2(2): 115-121, 2007. Link to article: http://www.insinet.net/rjmms/2007/115-121.pdf 36. Yuko Nagaoka, Maruf Ahmed, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Masaji Ishiguro, Takashi Nakamura, Masatomo Watanabe and Takafumi Nagatomo, Amino acids of the human 1d-adrenergic receptor involved in antagonist binding, Journal of Pharmacological Sciences, 106: 114 120, 2008. Link to article: http://www.jstage.jst.go.jp/article/jphs/106/1/114/_pdf 37. Maruf Ahmed, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Masaji Ishiguro, Takashi Tanaka, Ikunobu Muramatsu, And Takafumi Nagatomo. Mutational analysis of the 1a-adrenergic receptor binding pocket of antagonists by radioligand binding assay. Biological and Pharmaceutical Bulletin, 31(4): 598-601, 2008. Link to article: http://www.jstage.jst.go.jp/article/bpb/31/4/598/_pdf

REFERENCES: 1) Dr. Takafumi Nagatomo Professor and Dean Department of Pharmacology, Faculty of Pharmaceutical Sciences Niigata University of Pharmacy and Applied Life Sciences 265-1 Higashijima, Niigata 956-8603 JAPAN Tel: +81-(0)25-025-5234 Fax: +81-(0)25-025-5135 Email: nagatomot@s4.dion.ne.jp 3) Dr. Reza-Ul-Jalil Professor Department of Pharmacy University of Dhaka Dhaka-1000, Bangladesh Tel:880-2-9120325 (Res) E-mail: jalil@bdonline.com

2) Dr. Md. Abdur Rashid Professor and Dean Faculty of Pharmacy University of Dhaka Dhaka-1000, Bangladesh Tel:880-2-9566799 (Res) Email: rashidma@aitlbd.net

4) Dr. Md. Anwar-Ul-Islam Professor Department of Pharmacy University of Rajshahi Rajshahi-6205, Bangladesh Tel: 880-721-750071 (Res) Email: profanwarulislam@yahoo.com