BIOORG1 Organic Chemistry 1 for Biology Majors COLLEGE: Science DEPARTMENT: Chemistry COURSE CODE: BIOORG1 CLASS DAYS

AND CLASS TIME: ___________ ROOM:___________ INSTRUCTOR: Name: _________________________________________________ Contact details: _________________________________________ Consultation hours: ______________________________________ COURSE DESCRIPTION: BIOORG1: Organic Chemistry 1 for Human Biology Majors is a 3 unit lecture course (Major) and a prerequisite to BIOORG2. This course covers a review of basic principles, nomenclature, as well as structure and reactive sites of organic molecules. It also discusses the different forms of isomerism, conformations and configurations of organic compounds. The course also covers the physical and chemical properties of alkanes, alkyl halides, alcohols, ethers, and epoxides. LEARNING OUTCOMES (LO): On completion of the course, the student is expected to be able to do the following: ELGA LEARNING OUTCOME Critical and Creative Thinker LO1: Write/draw molecular structures and apply the International Union of Effective Communicator Pure and Applied Chemistry (IUPAC) rules in naming organic compounds. Lifelong Learner Service Driven Citizen LO2: Predict the physical properties such as melting point, boiling point and solubility of organic molecules based on their polarity and three dimensional structures. LO3: Use electronic effects (hyperconjugation, inductive effect, and resonance) or structural effects to predict chemical behaviors of organic compounds and recognize how extensively organic substances affect human lives and the environment. LO4: Recognize isomeric compounds and realize that a small difference in structure and orientation greatly affects their physical properties and bioactivity. LO5: Confidently show the synthetic steps in the preparation of organic molecules and identify/write the most likely mechanism using curved arrows for each step to show the conversion of one organic compound to another. FINAL COURSE OUTPUT: As evidence of attaining the above learning outcomes, the student is required to accomplish the tasks below. LEARNING OUTCOME REQUIRED OUTPUT DUE DATE LO1: Write/draw molecular structures and apply Effectively communicate in class Week 5 onwards the International Union of Pure and Applied (Five-minute presentation) a (two to three Chemistry (IUPAC) rules in naming organic specific organic compound of students presenting compounds. interest containing an assigned in a meeting) functional group. The report LO2: Predict the physical properties such as should show the molecular melting point, boiling point and solubility of structure of the compound, its organic molecules based on their polarity and three IUPAC name, properties (physical dimensional structures. and chemical), its synthesis and related compounds. The report LO3: Use electronic effects (hyperconjugation, should also highlight the impact of inductive effect, and resonance) or structural its use to the community and/or the effects to predict chemical behaviors of organic environment. compounds and recognize how extensively organic substances affect human lives and the environment.

LO5: Confidently show the synthetic steps in the preparation of organic molecules and identify/write the most likely mechanism using curved arrows for each step to show the conversion of one organic compound to another. RUBRIC FOR ASSESSMENT: Criterion Very Satisfactory/4 Organization Presentation is (25%) well organized and complete Scientific Scientific Accuracy information or (50%) facts presented/cited are 100% accurate. Presentation Presentation is (25%) very lively and interesting. The student was able to answer all questions from the class. Good/3 Presentation is organized but not complete Scientific information or facts presented/cited show some inaccuracies. Presentation is lively and generates the interest of the viewer. The student was able to answer some questions from the class. Satisfactory/2 Presentation is not organized, but complete. Scientific information or facts presented/cited show a significant number of inaccuracies. Presentation is not that lively but generates the interest of the viewer. The student was able to answer some questions from the class Needs Improvement/1 Presentation is not organized and incomplete. Scientific information or facts presented or cited are all inaccurate. Presentation is boring, does not generate the interest of the viewer, and the student was not able to answer questions from the class

OTHER REQUIREMENTS AND ASSESSMENTS: Aside from the final output, the student will be assessed at other times during the term by the following: Written Exams Homework/Problem Sets GRADING SYSTEM: The student will be graded according to the following: Long Exams 60% Problem Sets/Quizzes/Presentation 15% Final Exam 25% Passing Grade Grading Scale 60-65.7 >65.7-71.4 LEARNING PLAN: LEARNING OUTCOME LO1: Write/draw molecular structures and apply the International Union of Pure and Applied Chemistry (IUPAC) rules in naming organic compounds. LO2: Predict the physical properties such as melting point, boiling point and solubility of organic molecules based on their polarity and three dimensional structures. 60% Grade 1.0 1.5 TOPIC Introduction to Organic Chemistry Chapter 1:Structure and Bonding 1.2 Bonding 1.3-1.4 Lewis Structures 1.5 Resonance 1.6 Determining Molecular Shape 1.7 Drawing Organic Structures 1.8 Hybridization 1.9 Ethane, Ethylene and Acetylene 1.10 Bond Length and Bond Strength 1.11 Electronegativity and Bond Polarity 1.12 Polarity of Molecules >71.4-77.1 >77.1-82.8 2.0 2.5 >82.8-88.5 >88.5-94.2 >94.2-100 WEEK NO. Week 1 Week 1-2 3.0 3.5 4.0 LEARNING ACTIVITIES Lecture Lecture Powerpoint Presentation Exercises Problem Set

chemical behaviors of organic compounds and recognize how extensively organic substances affect human lives and the environment.

LO4: Recognize isomeric compounds and realize that a small difference in structure and orientation greatly affects their physical properties and bioactivity.

LO1: Write/draw molecular structures and apply the International Union of Pure and Applied Chemistry (IUPAC) rules in naming organic compounds. LO5: Confidently show the synthetic steps in the preparation of organic molecules and identify/write the most likely mechanism using curved arrows for each step to show the conversion of one organic compound to another.

Chapter 3: Introduction to Organic Molecules and Functional Groups 3.1-3.2 Functional Groups 3.3 Intermolecular Forces 3.4 Physical Properties 3.5-3.8Applications Exam1 Chapter 4: Alkanes 4.1-4.2 Alkanes and Cycloalkanes 4.3-4.6 Naming of Alkanes and Cycloalkanes 4.7-4.8 Physical Properties of Alkanes 4.9-4.13 Conformations of Alkanes and Cycloalkanes 4.14 Oxidation of Alkanes 4.15 Lipids Chapter 5: Stereochemistry 5.1- 5.2 Isomers 5.3 Chiral and Achiral Molecules 5.4 -5.6 Stereogenic Centers 5.7 Diastereomers 5.8 Meso Compounds 5.9 R and Assignments in Compounds with Two or More Stereogenic Centers 5.10 Disubstituted Cycloalkanes 5.12-5.13 Physical and Chemical Properties of Stereoisomers Exam2 Chapter 6: Understanding Organic Reactions 6.1 Writing Equations for Organic Reactions 6.2 Kinds of Organic Reactions 6.3 Bond Breaking and Bond Making 6.7-6.8 Energy Diagrams 6.9 Kinetics 6.10 Catalysts 6.11 Enzymes Chapter 7 Alkyl Halides and Nucleophilic Substitution 7.1 -7.4 Nomenclature and Physical Properties of Alkyl Halides 7.5 The Polar Carbon Halogen Bond 7.6 Nucleophilic Substitution 7.7 The Leaving Group 7.8 The Nucleophile 7.11-7.12 SN2 Mechanism 7.13-7.16 SN1 Mechanism 7.17-7.18 SN1 or SN2 Chapter 8 Alkyl Halides and Elimination Reactions 8.1-8.3 Elimination Reactions 8.4-8.5 E2 Mechanism and Zaitsev Rule 8.6 E1 Mechanism 8.7 SN1 nad E1 Reactions 8.8 Stereochemistry of E2 Reaction 8.9 E1 or E2 8.10 E2 and Alkyne Synthesis 8.11 When is the reaction SN1, SN2, E1 or E2 Exam 3 Chapter 9 Alcohols, Ethers and Epoxides

Week 3-4

Lecture Powerpoint Presentation Exercises Written Exam Lecture Powerpoint Presentation Exercises

Week 4 Week 5

Week 6-7

Lecture Powerpoint Presentation Exercises

Week 8 Week 8

Written Exam Lecture Powerpoint Presentation Exercises Problem Set

Week 9-10

Lecture Powerpoint Presentation Exercises

Week 11

Week 12 Week 13

Written Exam

Textbook: Smith, J.G. Organic Chemistry, 3rd Ed.; Mc Graw-Hill Companies, Inc.: USA, 2011 References: McMurry, J. E. Organic Chemistry, 8th Ed.; Brooks/Cole, Cengage Learning, Inc.: USA, 2012. Solomons, G.T.W.; Fryhle, C. B. Organic Chemistry, 10th Ed.; John Wiley & Sons (Asia) Pte Ltd: USA, 2011. McMurry, J. Organic Chemistry with Biological Applications, 2nd Ed.; Brooks/Cole, Cengage Learning, Inc.: USA, 2011. Wade, L.G. Organic Chemistry, 7th Ed.; Prentice Hall International: New Jersey, 2009. ONLINE RESOURCES: On-Line Learning Center for "Organic Chemistry" (J. G. Smith). www.mhhe.com/smith3e

CLASS POLICIES: Students are required to submit their problem sets and assignments on time. They are also required to take written examinations. Failure to take an exam on the scheduled date will result in a grade of zero in the long exam. Make-up exams will be given only given to students with reasonable excuses (in reference to DLSU-Manila student handbook). Except those students in the Deans List, students exceeding more than 5 absences will automatically get a final grade of 0.0.