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1. A patient begain to receive intravenous antibiotics dissolved in sterile saline solution developed fever within an hour.

(The solution in which antibiotics were dissolved had been sterilized by autoclaving.) The IV infusion was stopped and the fluid cultured, but cultures on a variety of media were sterile. Which of the following bacterial components would have been most effective in producing the patient's fever? A. Spores B. Lipopolysaccharide. C. Capsule polysaccharide. D. Outer membrane proteins. E. Siderophores. Three days after an appendectomy, a patient develops high fever. The patient's vital signs include a dangerously low blood pressure. The patient's erythrocyte sedimentation rate (ESR) is above-normal. Which of the cytokines below most directly contributed to development of these symptoms? A. IL-4 B. IFN-gamma C. IL-8 D. IL-10 E. TNF-alpha A hospitalized patient spikes a fever. Lactose-fermenting Gram-negative rods are isolated from a blood culture. Which of the following, produced in response to infection, played the largest role in producing the fever? A. C3b B. IL-1 C. IL-2 D. IL-8 E. Interferon-alpha Toxin of Vibrio cholerae is: A. LOS B. Cholera toxin - activates adenylate cyclase C. Toxin A - enterotoxin D. LPS E. ShET 1 The following statement are true of typhoid fever: A. The incubation period for enteric fever is 3-60 days, but symptoms typically occur in 3-5 weeks B. Patients who continue to shed bacteria for more than 1 month are considered chronic carriers C. Detection of persistently high H antibody offers an additional way of screening for long-term carriers D. Widal's test shows cross-reactivity with some other Salmonella species E. Blood culture culture is more sensitive than bone marrow Drug of choice for enteric fever in children is: A. cotrimoxazole B. ceftriaxon C. chloramphenicol D. ampicillin E. quinolone

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7. Oxygen requirements of Salmonella spp. is: A. Microaerophilic B. Aerobic C. Facultative anaerobe D. Obligate anaerobe E. Obligate aerobe 8. Morbidity of Bordetella pertussis is: A. Folliculitis B. Urinary tract infections C. Neonatal meningitis D. Conjunctivitis E. Whooping cough 9. This specimen can give the highest positivity for Salmonella typhi culture A. blood B. urine C. faeces D. bone marrow aspirate E. bile aspirate 10. Prolonged fever with neutropenia can be seen in A. dengue fever B. measles C. typhoid fever D. diphtheria E. varicella 11. Toxin of Shigella spp. is: A. Yst II B. Enterotoxins C. Cholera toxin - activates adenylate cyclase D. Leukocidin E. LPS

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