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Carpio, Charlene N.

2MT-P English 3- Second Draft

A View on Yellow Disease

To my classmates, to my professor, Mr. Arlo Mortos, Good afternoon. As you know, my name is Charlene Carpio, and I'm pleased to talk with you a topic entitled, A View on Yellow Disease. The subject of my presentation is liver cirrhosis. I will be discussing its signs and symptoms, causes and treatment of this disease. I hope that you find this presentation interesting. Okay, lets get started! The term cirrhosis is a symptom that refers to the orange or tawny color of a diseased liver. Liver cirrhosis is the degeneration of tissue in an organ resulting in fibrosis, with nodule and scar formation throughout the liver. The clinical features of cirrhosis result from hepatic cell dysfunction, portosystemic shunting, and portal hypertension. Based from Current Medical Diagnosis and Treatment 2011, patients with cirrhosis may have few or no symptoms of liver disease. Some of the symptoms may be nonspecific, that is, they don't suggest that the liver is their cause. Symptoms may be perilous, less often, abrupt. Yellowing of the skin (jaundice) due to the accumulation of bilirubin in the blood, weakness, fatigue, disturbed sleep, muscle cramps and weight loss are some of the more common symptoms and signs of liver cirrhosis. Abdominal pain may be present, menstrual abnormalities, loss of libido, sterility, gynecomastia in men may occur and testicular atrophy because of primary gonadal injury or suppression of hypothalamic or pituitary function. Skin manifestation consist of spider angioma, palmar arythma and Dupuytrens contracture.

Liver cirrhosis can be caused by a number of agents leading to the symptoms that I have said a while ago. More common are habitual alcohol consumption, chronic hepatitis B, C or D, and non-alcoholic fatty liver disease a condition that is associated with obesity, diabetes, malnutrition and certain drugs such as steroids. Chronic alcoholism is the number one most common cause of liver cirrhosis. Alcohol seems to injure the liver by blocking the normal metabolism of protein, fats, and carbohydrates. As Dr. Eduardo Gonzales stated in his medical notes, chronic hepatitis B is a major public health problem in the country. It afflicts between 10-12% of all Filipinos, (i.e., more than 8 million Filipinos). The hepatitis B virus (HBV) is mainly transmitted by the parenteral route (i.e., use of contaminated needle for injection and transfusion of infected blood) and by sexual intercourse. But the virus also spreads through contact with body fluids like saliva, tears, breast milk and urine. An infected mother can likewise transmit the virus to her baby during delivery. In most cases, hepatitis B is a self-limiting disease that leaves no permanent damage to the liver. However, in about 10% of people that get the infection, the virus persists for months to years and results in chronic hepatitis B, which results in progressive damage to the liver and eventually, cirrhosis. According to Dr. Lee of medicinenet.com, the liver damage that accompanies cirrhosis is irreversible. The goals of treatment are to slow down or stop the formation of scar tissue and prevent or manage the lifethreatening complications of the disease. Treatment of cirrhosis includes preventing further damage to the liver, treating the complications of cirrhosis, preventing liver cancer or detecting it early, and liver transplantation. In alcoholic cirrhosis: abstinence from alcohol and intake of an adequate wholesome diet; in cirrhosis caused by viral hepatitis: use of experimental approaches that include the use of drugs to improve immune responses to viral infection (interferon) or to help destroy the virus; in certain types of cirrhosis caused by chronic hepatitis: corticosteroids are indicated;










soluble vitamins may be helpful.

To wrap it up, Cirrhosis of the liver interferes with the liver's metabolism of nutrients, detoxification of the blood, bile production, and other normal functions. its damage is irreversible. Signs and symptoms typically occur after at least 10 years of alcohol abuse and develop slowly over the following weeks to months. In as much as cirrhosis can be caused by a variety of factors, the specific treatment for the condition depends on the underlying cause. Let me leave you with these closing thoughts, Every day you do one of two things: build health or produce disease in yourself. Thank you for listening.