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Humans. ProQuest document link Abstract: Myopia is a refractive error of the eye that has a significant socioeconomic impact due to its increasing prevalence and the fact that it causes visual impairment.org/10. Genetic Predisposition to Disease. a productive avenue will open up for deciphering the aetiological heterogeneity of myopia and the biological pathways underlying its development. F K.physiopathology. Vision Disorders -.7-8 (Apr 2005): 800-8. neurotransmitters and transcription factors. such as cytokines. in myopia development has been indicated through various lines of investigation. Tight environmental influence is exemplified by defocus-induced myopia produced in animal models.genetics (major). Zrenner.1007/s00018-004-4353-z 26 July 2013 Page 3 of 5 ProQuest . Refraction.physiopathology. Myopia -. E. Genetic linkage.complications. Genotype & phenotype MeSH: Animals.doi. Vision Disorders -. M. Vision Disorders -. Ocular. Pusch.Document 1 of 1 A genetic perspective on myopia Author: Jacobi. Its aetiology is complex and is likely to involve the interaction of environmental and genetic influences.complications. (major).[PUBLICATION ABSTRACT] Subject: Genetics. particular interest focussing on scleral extracellular matrix proteins and developmental genes of the eye. C M Publication info: Cellular and Molecular Life Sciences 62. As high-throughput technology for largescale genotyping and RNA expression analysis enters the field of myopia research. Myopia. Myopia -. Broghammer. while genetic factors predominate in familial occurrence of myopia with a Mendelian inheritance pattern. Myopia -. The involvement of numerous mediators.genetics (major) Publication title: Cellular and Molecular Life Sciences Volume: 62 Issue: 7-8 Pages: 800-8 Publication year: 2005 Publication date: Apr 2005 Year: 2005 Publisher: Springer Science & Business Media Place of publication: Basel Country of publication: Netherlands Publication subject: Sciences: Comprehensive Works ISSN: 1420-682X Source type: Scholarly Journals Language of publication: English Document type: Journal Article Document feature: References DOI: http://dx.

Accession number: 15868405 ProQuest document ID: 346821422 Document URL: http://search.com/docview/346821422?accountid=49910 Copyright: Birkhäuser Verlag.proquest. Basel 2005 Last updated: 2013-02-06 Database: ProQuest Health & Medical Complete.ProQuest Research Library: Science & Technology 26 July 2013 Page 4 of 5 ProQuest .

Zrenner. A genetic perspective on myopia.Bibliography Citation style: APA 6th . Broghammer. (2005).doi. . M.. All rights reserved. F. doi:http://dx.. C.American Psychological Association. M. Cellular and Molecular Life Sciences. 6th Edition Jacobi. 800-8.1007/s00018-004-4353-z _______________________________________________________________ Contact ProQuest Copyright © 2012 ProQuest LLC. E. & Pusch. K.. 62(7-8).Terms and Conditions 26 July 2013 Page 5 of 5 ProQuest .org/10.

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