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Genotype & phenotype MeSH: Animals.doi. Ocular. Refraction. while genetic factors predominate in familial occurrence of myopia with a Mendelian inheritance pattern. The involvement of numerous mediators.Document 1 of 1 A genetic perspective on myopia Author: Jacobi. As high-throughput technology for largescale genotyping and RNA expression analysis enters the field of myopia research. M. Zrenner. Tight environmental influence is exemplified by defocus-induced myopia produced in animal models. (major).physiopathology.genetics (major) Publication title: Cellular and Molecular Life Sciences Volume: 62 Issue: 7-8 Pages: 800-8 Publication year: 2005 Publication date: Apr 2005 Year: 2005 Publisher: Springer Science & Business Media Place of publication: Basel Country of publication: Netherlands Publication subject: Sciences: Comprehensive Works ISSN: 1420-682X Source type: Scholarly Journals Language of publication: English Document type: Journal Article Document feature: References DOI: http://dx.complications. E. Humans. Myopia -. particular interest focussing on scleral extracellular matrix proteins and developmental genes of the eye. in myopia development has been indicated through various lines of investigation.complications.1007/s00018-004-4353-z 26 July 2013 Page 3 of 5 ProQuest . Vision Disorders -.7-8 (Apr 2005): 800-8. Genetic linkage. Myopia -.genetics (major). F K. Its aetiology is complex and is likely to involve the interaction of environmental and genetic influences.[PUBLICATION ABSTRACT] Subject: Genetics. a productive avenue will open up for deciphering the aetiological heterogeneity of myopia and the biological pathways underlying its development. such as cytokines. Vision Disorders -. neurotransmitters and transcription factors. Broghammer. Vision Disorders -. Myopia.physiopathology.org/10. C M Publication info: Cellular and Molecular Life Sciences 62. Genetic Predisposition to Disease. Myopia -. ProQuest document link Abstract: Myopia is a refractive error of the eye that has a significant socioeconomic impact due to its increasing prevalence and the fact that it causes visual impairment. Pusch.

Basel 2005 Last updated: 2013-02-06 Database: ProQuest Health & Medical Complete.com/docview/346821422?accountid=49910 Copyright: Birkhäuser Verlag.ProQuest Research Library: Science & Technology 26 July 2013 Page 4 of 5 ProQuest .proquest.Accession number: 15868405 ProQuest document ID: 346821422 Document URL: http://search.

1007/s00018-004-4353-z _______________________________________________________________ Contact ProQuest Copyright © 2012 ProQuest LLC.American Psychological Association. 800-8. All rights reserved.. doi:http://dx. . Broghammer. Cellular and Molecular Life Sciences.Terms and Conditions 26 July 2013 Page 5 of 5 ProQuest . M. & Pusch.. A genetic perspective on myopia. C. (2005). Zrenner. K.. 6th Edition Jacobi.Bibliography Citation style: APA 6th . 62(7-8).doi. M. F.org/10. E.