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Humans. Vision Disorders -.Document 1 of 1 A genetic perspective on myopia Author: Jacobi. Genetic linkage. Myopia -. while genetic factors predominate in familial occurrence of myopia with a Mendelian inheritance pattern. Zrenner. neurotransmitters and transcription factors. Genetic Predisposition to Disease. Myopia -. particular interest focussing on scleral extracellular matrix proteins and developmental genes of the eye. Pusch.7-8 (Apr 2005): 800-8. in myopia development has been indicated through various lines of investigation. Myopia. E. Broghammer. F K.physiopathology. Ocular.physiopathology. C M Publication info: Cellular and Molecular Life Sciences 62. Tight environmental influence is exemplified by defocus-induced myopia produced in animal models.org/10.genetics (major) Publication title: Cellular and Molecular Life Sciences Volume: 62 Issue: 7-8 Pages: 800-8 Publication year: 2005 Publication date: Apr 2005 Year: 2005 Publisher: Springer Science & Business Media Place of publication: Basel Country of publication: Netherlands Publication subject: Sciences: Comprehensive Works ISSN: 1420-682X Source type: Scholarly Journals Language of publication: English Document type: Journal Article Document feature: References DOI: http://dx. ProQuest document link Abstract: Myopia is a refractive error of the eye that has a significant socioeconomic impact due to its increasing prevalence and the fact that it causes visual impairment. Genotype & phenotype MeSH: Animals. Its aetiology is complex and is likely to involve the interaction of environmental and genetic influences. Refraction.complications. Myopia -. M. Vision Disorders -.genetics (major).1007/s00018-004-4353-z 26 July 2013 Page 3 of 5 ProQuest .[PUBLICATION ABSTRACT] Subject: Genetics.complications. such as cytokines.doi. As high-throughput technology for largescale genotyping and RNA expression analysis enters the field of myopia research. a productive avenue will open up for deciphering the aetiological heterogeneity of myopia and the biological pathways underlying its development. Vision Disorders -. The involvement of numerous mediators. (major).

Accession number: 15868405 ProQuest document ID: 346821422 Document URL: http://search.proquest.ProQuest Research Library: Science & Technology 26 July 2013 Page 4 of 5 ProQuest . Basel 2005 Last updated: 2013-02-06 Database: ProQuest Health & Medical Complete.com/docview/346821422?accountid=49910 Copyright: Birkhäuser Verlag.

. . 800-8. All rights reserved.1007/s00018-004-4353-z _______________________________________________________________ Contact ProQuest Copyright © 2012 ProQuest LLC.org/10. (2005). K. F. 6th Edition Jacobi. doi:http://dx. & Pusch. M. Zrenner. Cellular and Molecular Life Sciences. C. E. A genetic perspective on myopia. 62(7-8)..Bibliography Citation style: APA 6th . Broghammer..Terms and Conditions 26 July 2013 Page 5 of 5 ProQuest .doi.American Psychological Association. M.

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