Brand Name: Pritor

Generic Name: Telmisartan

Indication: Hypertension (used alone or with other antihypertensive)
Drug Classification: Antihypertensive (angiotension II antagonist)
Mechanism of Action: Blocks the vasoconstricting and aldosterone- secreting effects of
angiotensin II by selectively blocking the binding of angiotensin I receptor in many
tissues, such as vascular smooth muscle and the adrenal gland.
Dosage: Adults: 40 mg PO daily
Special Precaution: Renovascular Hypertension, renal impairment and kidney transplant,
intravascular volume depletion, other conditions with stimulation of the renin
– angiotensin – asdosterone system, primary aldosteronism, aortic and Mitral
stenosis, obstructive Hypertrophic cardiomyopathy, Hyperkalemia, Hepatic impairment.
Pregnancy Risk Category: C (D in second and third trimesters)
Adverse Reaction:
CNS: dizziness, pain, fatigue, Headache. CV: Chest pain, hypertension, Peripheral
edema. EENT: pharyngitis sinusitis. GI: abdominal pain, diarrhea,
Dyspepsia, nausea. GU: urinary tract infection. Musculoskeletal: back pain,
Myalgia. Respiratory: cough, upper. Respiratory tract infection
Other: flu like symptoms
Contraindications: Contraindicated in patients hypersensitive to drug or its components.
Form: Tablets – 40 mg, 80 mg
Nursing Responsibility:
 drugs that react on the renin – angiotensin system can cause fetal and neonatal
morbidity and death when given to pregnant women. These problems haven’t been
detected when exposure has been limited to the first trimester.
 Use cautiously in patients with biliary obstruction disorders or Renal and hepatic
insufficiency and in those with and activated Renin angiotension system such as
volume or salt depleted patients
 Monitor patient for hypotension after starting drug. Place patient supine if
hypotension occurs, and give I.V. normal saline is needed.
 Most of the antihypertensive effect occurs within 2 weeks. Maximal blood pressure
reduction is usually reached after 4 weeks. Diuretics may be added if blood pressure
isn’t controlled by drug alone.
 For patients whose renal function may depend on the activity of the renin-
angiotensin-aldosterone system (such those with sever heart failure), treatment with
ACE inhibitors and angiotensin receptor antagonists has cause oliguria or
progressive azotemia and (rarely) acute renal failure.
 Drug isn’t removed by hemodialysis. Patients undergoing dialysis may develop
orthostatic hypotension. Closely monitor blood pressure.