Brand name: Solu-cortef

Generic name: Hydrocortisone

Indication: management of adrenocortical insufficiency, relief inflammation of
corticosteroid-responsive dermatoses, adjunctive treatment of ulcerative colotis
Drug classification: anti-inflammatory agent, corticosteroid, glucocorticoid
mineralocorticoid
Mechanism of action: decreases inflammation by suppression of migration of
polymorphonuclear leukocytes and reversal of increased capillary permeability
Dosage: Adult 100-500mg IV over a period of 30sec-10min, Children/infant: not
<25mg/day
Special precaution: hyperthyroidism, cirrhosis, nonspecific ulcerative colitis,
hypertension, osteoporosis, thromboembolic tendencies, CHF, convulsive
disorders, myasthenia gravis, thrombophlebitis, peptic ulcer, diabetes
Pregnancy risk category: C
Adverse reaction: CNS: insomnia, nervousness GI: increased appetite Derma:
hirsutism Endo: diabetes mellitus Resp: epistaxis other: cataracts, anthralgia
Contraindications: serious infections, except septic shock or tuberculosis meningitis,
hypersensitivity, viral, fungal or tubercular skin lesions
Form: Aerosol 10%, cream 0.5%, injection, suspension 25mg/ml, ointment 0.5%,
suppository 10mg, tablets 10mg
Nursing responsibilities:
 Monitor any sign of anaphylactic reaction
 Assess client’s urine, muscle weakness and wasting, weight