Promixin

Promixin1millionunitpowderfornebulisersolutionunitdosevials Whenusedincertaintypesofbacterialinfections Promixin(Prohmixin)isamedicinewhichisused incertaintypesofbacterialinfectionsandcystic fibrosis.Promixincontainscolistimethatesodium.It issuppliedbyProfilePharmaLimited. Yourmedicine Promixinisusedtotreatcertaintypesoflung infectionsinpeoplewithcysticfibrosis.Itworksby killingcertaintypesofbacteria. Donotshareyourmedicinewithotherpeople.It maynotbesuitableforthemandmayharmthem. Thepharmacylabelonyourmedicinetellsyouhow muchmedicineyoushoulduse.Italsotellsyouhow oftenyoushoulduseyourmedicine.Thisisthe dosethatyouandyourprescriberhaveagreedyou shoulduse.Youshouldnotchangethedoseofyour medicineunlessyouaretoldtodosobyyour prescriber. Ifyoufeelthatthemedicineismakingyouunwellor youdonotthinkitisworking,thentalktoyour prescriber. Whentotakeyourmedicine Somemedicinesworkbestiftheyaretakenata specifictimeofday.Gettingthemostfromyour medicinecanalsobeaffectedbywhatyoueat, whenyoueatandthetimesatwhichyoutakeother medicines.Makesureyoufollowanyspecific instructionsgiventoyoubyyourprescriberorthat areinthePatientInformationLeafletthatcomes withthismedicine. Howtotakeyourmedicine Thismedicineneedstobereconstitutedbeforeyou inhaleitthroughanebuliser.Specialinstructionsfor preparingthemedicinewillbegiventoyoubyyour prescriberandcanbefoundinthePatient InformationLeafletthatcomeswiththismedicine.If youhaveanyconcernsaboutthismedicineorhow touseit,talktosomeonewhoisinvolvedinyour medicalcare. InthecaseofPromixin: breatheinPromixinthroughthemouth,try nottoswallowthemedicine followyourdoctor'sinstructionsandmake sureyoureadthelabelonyourmedicine whichwillgiveyouinformationonhowtouse yourmedicineandwhentotakeit followtheadviceonthebesttechniquesfor usingthismedicinewhichyouwillfindinthe patientinformationleafletthatcomeswith yourmedicine ifyouareunsurehowtouseyournebuliser orarehavingproblemsyoushoulddiscuss Providedbywww.medicines.org.uk/guides thesedifficultieswithyourprescriber, pharmacistorcysticfibrosisnurse donotmixothernebulisersolutionswiththis medicine disposeofanyremainingsolutionafterusing Promixin useimmediatelyafterithasbeenprepared Ifyouarehavingproblemstakingthismedicine,you shouldtalktoyourprescriberorpharmacist.They maybeabletogiveyouadviceonotherwaysto takeyourmedicineorothermedicinesthatare easierforyoutotake. Takingtoomuchofyourmedicine Takingextradosesofsomemedicinescanbe harmful.Insomecasesevenoneextradosecan causeyouproblems.Ifyoutakeextradosesofyour medicine,youmustgetmedicaladviceimmediately. Youmayneedatesttoassesstheeffectoftaking extradoses.Thisisbecausetheeffectsoftaking toomuchmedicineareverycomplexsoitisvery importantthatyouseekmedicaladvice. Contactyourprescriber,pharmacist,specialistclinic orNHSDirecton08454647foradvice. Makesureyoutakeallofyourmedicinecontainers withyouifyouareadvisedtogotohospital. Stoppingyourmedicine Ifyouarehavinganyproblemsusingyourmedicine youmustspeaktoyourprescriber.Ifyouarenot havinganyproblemsusingthismedicinethendo notstopusingit,evenifyoufeelbetter,unless advisedtodosobyyourprescriber. Ifyouareinanydoubt,contactyourprescriber, pharmacist,specialistclinicorNHSDirecton0845 4647. Lookingafteryourmedicine Theinstructionsonhowyoushouldkeepyour medicineareonthepharmacylabel.Youshould keepyourmedicineintheoriginalcontainer.This willhelptokeepyourmedicineinthebestcondition andalsoallowyoutochecktheinstructions.Donot takethemedicineifthepackagingappearstohave beentamperedwithorifthemedicineshowsany signsofdamage.Makesurethatthemedicineisout ofthesightandreachofchildren. InthecaseofPromixin: therearenospecialinstructionsonhowto lookafteryourmedicine Youmustnottakethemedicineaftertheexpirydate shownonthepackaging.Ifyouhaveanyunused medicine,returnittoyourpharmacistwhowill disposeofitsafely. Whetherthismedicineissuitableforyou Promixinisnotsuitableforeveryoneandsome peopleshouldneveruseit.Otherpeopleshould onlyuseitwithspecialcare.Itisimportantthatthe personprescribingthismedicineknowsyourfull medicalhistory. Yourprescribermayonlyprescribethismedicine withspecialcareormaynotprescribeitatallifyou: areallergicorsensitivetoorhavehada reactiontoanyoftheingredientsinthe medicine havemyastheniagravis havekidneyproblems haveporphyria areallergicorsensitivetoorhavehadabad reactiontopolymyxinsinthepast Furthermoretheprescribermayonlyprescribethis medicinewithspecialcareormaynotprescribeitat allforachildundertwoyearsofage. Aspartoftheprocessofassessingsuitabilityto takethismedicineaprescribermayalsoarrange tests: todeterminewhetherornotthemedicineis suitableandwhetheritmustbeprescribed withextracare toconfirmthatthisistherightdose tocheckthatthismedicineisnothavingany undesiredeffects OvertimeitispossiblethatPromixincanbecome unsuitableforsomepeople,ortheymaybecome unsuitableforit.Ifatanytimeitappearsthat Promixinhasbecomeunsuitable,itisimportantthat theprescriberiscontactedimmediately. Sideeffects Amedicineisonlymadeavailabletothepublicifthe clinicaltrialshaveshownthatthebenefitsoftaking themedicineoutweightherisks. Onceamedicinehasbeenlicensed,informationon themedicine'seffects,bothintendedand unintended,iscontinuouslyrecordedandupdated. Somesideeffectsmaybeseriouswhileothersmay onlybeamildinconvenience. Everyone'sreactiontoamedicineisdifferent.Itis difficulttopredictwhichsideeffectsyouwillhave fromtakingaparticularmedicine,orwhetheryou willhaveanysideeffectsatall.Theimportantthing istotellyourprescriberorpharmacistifyouare havingproblemswithyourmedicine. Verycommon:Morethan1in10peoplewhouse Promixin nebulisationproblemssuchascoughor bronchospasmseekmedicaladviceifyou developacough,tightnessinthechest, bronchoconstrictionorbronchospasm Thefrequencyofthesesideeffectsisunknown hypersensitivityreactionssuchasskinrash seekmedicaladviceifyouget hypersensitivityreactions kidneyproblemsthesehavebeenreported inpeoplewhohavebeengivenhighdosesof Promixininjection neurotoxicityincludingdizziness,vertigo, facialparaesthesia,slurredspeech,eyeor eyesightproblems,vasomotorinstability, confusion,psychosisorapnoeaneurotoxic effectsmayoccurifhighdosesofPromixin aregiven overgrowthofmicroorganismsthatarenot affectedbyPromixin soremouth sorethroat Ifyoufeelunwellorifyouhaveconcernsabouta sideeffect,tellthepersonlookingafteryou immediately. Takingothermedicines Ifyouaretakingmorethanonemedicinetheymay interactwitheachother.Attimesyourprescriber maydecidetousemedicinesthatinteract,inother casesthismaynotbeappropriate. Thedecisiontousemedicinesthatinteractdepends onyourspecificcircumstances.Yourprescribermay decidetousemedicinesthatinteract,ifitisbelieved thatthebenefitsoftakingthemedicinestogether outweightherisks.Insuchcases,itmaybe necessarytoalteryourdoseormonitoryoumore closely. Tellyourprescriberthenamesofallthemedicines thatyouaretakingsothattheycanconsiderall possibleinteractions.Thisincludesallthemedicines whichhavebeenprescribedbyyourGP,hospital doctor,dentist,nurse,healthvisitor,midwifeor pharmacist.Youmustalsotellyourprescriberabout medicineswhichyouhaveboughtoverthecounter withoutprescriptions. ThefollowingmedicinesmayinteractwithPromixin: cephalothinsodium Thefollowingtypesofmedicinemayinteractwith Promixin: medicinesthataredamagingtothekidney Lastupdated05Dec11 Copyright2010Datapharm

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Promixin
Promixin1millionunitpowderfornebulisersolutionunitdosevials Whenusedincertaintypesofbacterialinfections aminoglycosides nondepolarisingmusclerelaxants medicinesthataredamagingtothenerves IfyouaretakingPromixinandoneoftheabove medicinesortypesofmedicines,makesureyour prescriberknowsaboutit. Complementarypreparationsandvitamins Medicinescaninteractwithcomplementary preparationsandvitamins.Ingeneral,thereisnot muchinformationavailableaboutinteractions betweenmedicinesandcomplementary preparationsorvitamins. Ifyouareplanningtotakeorarealreadytakingany complementarypreparationsandvitaminsyou shouldaskyourprescriberwhetherthereareany knowninteractionswithPromixin. Yourprescribercanadvisewhetheritisappropriate foryoutotakecombinationsthatareknownto interact.Theycanalsodiscusswithyouthe possibleeffectthatthecomplementarypreparations andvitaminsmayhaveonyourcondition. Ifyouexperienceanyunusualeffectswhiletaking thismedicineincombinationwithcomplementary preparationsandvitamins,youshouldtellyour prescriber. Drivingandoperatingmachinery Whentakinganymedicineyoushouldbeawarethat itmightinterferewithyourabilitytodriveoroperate machinerysafely. InthecaseofPromixin: thismedicinecouldaffectyourabilitytodrive oroperatemachinery Youshouldseehowthismedicineaffectsyou beforeyoujudgewhetheryouaresafetodriveor operatemachinery.Ifyouareinanydoubtabout whetheryoushoulddriveoroperatemachinery,talk toyourprescriber. Diet Medicinescaninteractwithcertainfoods.Insome cases,thismaybeharmfulandyourprescribermay adviseyoutoavoidcertainfoods. InthecaseofPromixin: therearenospecificfoodsthatyoumust excludefromyourdietwhenusingPromixin Alcohol Alcoholcaninteractwithcertainmedicines. InthecaseofPromixin: therearenoknowninteractionsbetween alcoholandPromixin Familyplanningandpregnancy Mostmedicines,insomeway,canaffectthe developmentofababyinthewomb.Theeffecton thebabydiffersbetweenmedicinesandalso dependsonthestageofpregnancythatyouhave reachedwhenyoutakethemedicine. InthecaseofPromixin: youshouldonlyusethismedicineduring pregnancyifyourdoctorthinksthatyouneed it Youneedtodiscussyourspecificcircumstances withyourdoctortoweighuptheoverallrisksand benefitsoftakingthismedicine.Youandyourdoctor canmakeadecisionaboutwhetheryouaregoingto takethismedicineduringpregnancy. IfthedecisionisthatyoushouldnothavePromixin, thenyoushoulddiscusswhetherthereisan alternativemedicinethatyoucouldtakeduring pregnancy. Breastfeeding Certainmedicinescanpassintobreastmilkand mayreachyourbabythroughbreastfeeding. InthecaseofPromixin: breastfeedingisnotrecommendedwhile usingthismedicine BeforeyouhavePromixinyoushoulddiscuss breastfeedingwithyourdoctorormidwife.Theywill helpyoudecidewhatisbestforyouandyourbaby basedonthebenefitsandrisksassociatedwiththis medicine.Ifyouwishtobreastfeedyoushould discusswithyourprescriberwhetherthereareany othermedicinesyoucouldusewhichwouldalso allowyoutobreastfeed. Ingredientsofyourmedicine Medicinescontainactiveingredients.Theymayalso containother,additionalingredientsthathelpensure thestability,safetyandeffectivenessofthe medicine.Theyarealsoaddedtoimprovethe medicine'sappearanceandtomakeiteasiertouse. Somemaybeusedtoprolongthelifeofthe medicine. Promixincontains: colistimethatesodium Ifyouarenotabletotakeanyoftheingredientsin yourmedicine,talktoyourprescriberorpharmacist toseeiftheycansuggestanalternativemedicine.If youhavereactedbadlytoPromixinbefore,donot Page2of2 Lastupdated05Dec11 Copyright2010Datapharm usePromixin.Talktoyourprescriber,pharmacistor nurseassoonaspossible.

Providedbywww.medicines.org.uk/guides