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INITIAL EVALUATION OF THE ACUTE

MULTIPLE-LIGAMENT-INJURED KNEE
TIMOTHY C. WILSON, MD, and DARREN L. JOHNSON, MD

The multiple-ligament-injured knee is an orthopaedic emergency. The initial assessment of this injury must
include a thorough and expedient physical examination, with particular attention directed to the vasculari~ of the
extremity. Vascular injuries should be ruled out immediately because a pulseless extremity may result in a below-
knee amputation if the leg is not reperfused within 6 to 8 hours. All patients with a normal vascular examination
must have serial pulse examinations or undergo an arteriogram, because intimal tears may present on a delayed
basis. The neurological examination, particularly of the peroneal nerve, should be documented. A detailed
examination of the knee ligaments is performed on the anterior cruciate ligament, posterior cruciate ligament,
medial collateral ligament, and posterolateral anatomic structures. Initial and postreduction radiographs require
thorough evaluation to assess for peri-articular fractures, direction of dislocation, and adequacy of reduction.
Magnetic resonance imaging will provide detailed information about the ligaments, bone or subchondral bone,
menisci, and articular cartilage. The physical examination must be correlated with the magnetic resonance imaging
findings for preoperative planning. This article provides a treatment algorithm that can be helpful in the initial
assessment and decision-making process of the multiple-ligament-injured knee.
KEY WORDS: knee dislocation, multiple-ligament-injured knee, vascular injury
© 2003 Elsevier Inc. All rights reserved.

A knee dislocation is one of the few true orthopaedic DEFINITION OF INJURY


emergencies. The initial management of these injuries
must be thorough and expedient. Failure to recognize the Many knee dislocations (>50%) spontaneously reduce be-
fore a physician's evaluation. Therefore, the term "multi-
full extent of these injuries may have disastrous compli-
pie-ligament knee injury" may be more appropriate. A
cations. Although a knee dislocation leading to a multi-
true knee dislocation implies complete displacement of the
ligament-injured knee is relatively uncommon, a multiple-
tibiofemoral articulation. This is seldom seen. For practical
ligament-injured knee has a high rate of associated injuries
consideration, a knee with 2 or more ligaments completely
that may be limb threatening. The actual incidence of these
disrupted should be classified as a multiple-ligament in-
injuries is unknown because most of these injuries present
jury or knee dislocation. 1 This diagnosis should alert the
spontaneously reduced and, therefore, are often misdiag-
examiner to associated injuries and their potentially dev-
nosed. Consequently, the treating physician must have a
astating complications.
high index of suspicion. To appropriately diagnose and
treat these injuries, the treating physician must have a full INCIDENCE
understanding of knee dislocations, their associated inju-
ries, and their potential complications. The true incidence of knee dislocations is unknown. Most
An appropriate history with a thorough physical exam- authors agree that the actual incidence is higher than the
ination is helpful in making the correct diagnosis, which 0.001% to 0.013% per year published in the literature. 2
will direct the next course of action. Specific tests such as Spontaneous reductions, other distracting injuries, and
radiographs, magnetic resonance imaging, and angio- examiner inexperience may account for this diagnosis of-
grams will provide useful information for diagnosis and ten being overlooked. All knees with 2 or more ligaments
management. Once a limb-threatening injury has been completely disrupted should be classified as a multi-liga-
ruled out, a preoperative plan can be established to ad- ment knee injury, requiring the treating physician to eval-
dress the ligament injuries. This article presents basic in- uate for secondary associated injuries with an appropriate
formation on knee dislocations, and provides a treatment examination and ancillary tests.
algorithm for the initial evaluation of multiple-ligament
CLASSI FICATION
knee injuries.
Historically, knee dislocations are classified according to
the position of the tibia in relation to the femur. Kennedy's
From the Kentucky Clinic, Lexington, KY. classification system described knee dislocations as ante-
Address reprint requests to Darren L. Johnson, MD, University of rior, posterior, medial, lateral, and rotational. Anterior
Kentucky School of Medicine, The Kentucky Clinic, K415, Lexington, KY
dislocations are the most common (40%), followed by
40536-0284.
© 2003 Elsevier Inc. All rights reserved. posterior (33%), lateral (18%), medial (4%), and rotational
1060-1872/03/1103-0003530.00/0 (5%).3 This classification system is limited because most
doi:10.1053/otsrn.2003.35912 dislocations spontaneously reduce.

Operative Techniques in Sports Medicine, Vol 11, No 3 (July), 2003: pp 187-t92 1 87


Schenk describes a classification system based on what Knowledge of each patient's mechanism of injury will
ligaments are torn. A KD I is an anterior dislocation with be useful in determining what structures may be injured,
the anterior cruciate ligament (ACL) torn and the posterior and the potential risk for associated injury.
cruciate ligament (PCL) intact. A KD II involves the ACL
and PCL with the collaterals intact. A KD III M is an ACL,
VASCULAR INJURIES
PCL, and medial collateral ligament (MCL) injury, and a
KD III L is an ACL, PCL, and lateral injury. A KD IV A knee dislocation should raise suspicion for a possible
involves injury to all 4 ligaments. 4 This classification was vascular injury. The most serious and limb-threatening
modified by Wascher to include a KD V, which includes a injury associated with a knee dislocation is a popliteal
peri-articular fracture. 5 The KD classification is useful with artery disruption or thrombosis. These injuries usually
regards to a specific ligament diagnosis. occur as the result of a traction injury or a complete
In addition to the anatomic classifications, there is a disruption. The popliteal artery is the main blood supply
difference between high energy and low energy with re- to the lower leg. The intimate anatomical relationship
gards to associated injuries. Low-energy dislocations have between the artery and the knee places the vessel at risk.
been shown to have a much lower incidence of associated Proximally, the vessel is tethered at "Hunter's canal" or
injuries, with vascular injury rates of 5%, meniscal injury adductor hiatus located at the adductor tubercle of the
rates of 20%, and an osteochondral fracture rate of 5%. 6 In femur. Distally, the vessel is tethered at the fibrous arch or
high-energy dislocations, the rate of popliteal artery injury trifurcation of the vessels at the soleus muscle. Within the
ranges from 14% to 65%. Fifty to 60% of patients will have popliteal space, the popliteal artery gives off the superior
fractures, and 41% of patients will have multiple fractures. lateral, superior medial, middle, inferior lateral, and infe-
Patients with these high-energy injuries often have other rior medial geniculate arteries. These branches do not
significant injuries to their head or chest, which precludes provide collateral flow to the lower leg in the case of a
early aggressive treatment of their knee ligaments. 5 popliteal artery injury.
The chronicity of the injury is also important with re- Vascular injuries can occur with all types of dislocations.
gards to associated injuries and surgical planning. Surgical The risk of arterial injury with knee dislocations is be-
treatment gives improved results in acute versus chronic tween 10% and 64o/0.7 Green and Allen reported rupture of
cases. Some structures may be repaired if treated acutely, the artery to be as high as 44% with posterior dislocations.
whereas late treatment may require a reconstruction pro- Anterior dislocations are associated with arterial injury as
cedure. Although there is no official classification with high as 39%, and the incidence with medial injury was
regard to timing, a knee dislocation is acute if seen within 25% and with lateral injury was 6%. 9 Kennedy showed
the first 3 weeks. Three weeks to 3 months may be con- that rupture of the popliteal artery occurs when the knee is
sidered subacute, and after 3 months, chronic. 7 This clas- forced beyond 50 ° of hyperextension.3 Complete rupture
sification takes into account that the acute knee injury has of the popliteal artery is more common with posterior
tissue that may be more easily repaired within the first few dislocations, and anterior dislocations more commonly
weeks. cause intimal tearing. The arterial ruptures associated with
posterior dislocations are usually obvious on examination
with loss of distal pulses. The intimal tears of the artery
MECHANISM may present in a delayed fashion and are more difficult to
The mechanism of injury provides useful information with diagnose. The initial physical examination may be com-
regards to the direction and degree of injury. Anterior and pletely normal in a knee with an intimal tear. Intimal tears
posterior dislocations are the most common. These injuries cause a gradual thrombosis, which may propagate to com-
are caused by force from the opposite direction. For ex- plete arterial occlusion. Therefore, it is recommended that
ample, a posterior dislocation is caused by an anterior these patients undergo admission to the hospital for close
blow to the knee. This injury pattern is commonly seen in observation of their vascular status for 48 to 72 hours. Any
the "dashboard knee." Anterior dislocations commonly change in vascular status mandates immediate evaluation
occur from extreme knee hyperextension. This happens and treatment.
when an anterior blow occurs to the tibia against a fixed The initial physical examination must include assess-
foot, and the femur is forced posterior to the tibia. Medial ment of the vascular status of the injured extremity. Ab-
and lateral dislocations are most likely to occur in high- sence of pulses is a vascular emergency. A warm foot with
energy accidents with varus and valgus rotational forces. 3 good capillary refill but absent pulses is not normal. Cap-
Knee dislocations can occur from a variety of mecha- illary refill is a poor indicator of blood flow. If the injured
nisms and can be divided into high velocity or low veloc- extremity is pulseless for 6 to 8 hours, then permanent
ity. The most common cause of knee dislocation is a motor damage may occur, and the amputation rate may be as
vehicle accident. These traumatic "high-velocity" knee high as 86%. This compares to an amputation rate of 13%
dislocations can occur as a result of a variety of forces, and when a vascular repair is performed within 8 hours. 9 If the
they have a high rate of associated injuries, s Knee dislo- knee is pulseless and still in a position of dislocation, then
cations can also result from sports-related, or low-velocity, the knee should be immediately reduced and the pulses
injuries. Shelborne reported the most commonly involved reassessed. Persistent absence of the pulses requires im-
sports were football (35%), wrestling (15%), and running mediate vascular surgery consultation. Time should not be
(10%). Low-velocity knee dislocations have a lower rate of wasted getting an arteriogram in the radiology suite or
associated injuries. 6 Industrial accidents and falls are other arranging any other study. The vascular surgeon can get
common mechanisms. 9 appropriate studies, such as an on-table arteriogram, in

188 WILSON AND JOHNSON


the operating room. A present pulse that is diminished skin necrosis. Compartment syndrome must always be
compared with the contralateral extremity necessitates ruled out, and emergent fasciotomies are required -when
further vascular study. As long as the extremity shows this condition exists or is impending.
signs of perfusion, such as good capillary refill, appropri-
ate color, and warmth, an angiogram may be performed in
INITIAL EVALUATION AND MANAGEMENT
the radiology suite. Abnormal pulses may develop as a
result of vessel spasm, thrombosis, or progression of an Although some knee dislocations present with obvious
intimal tear. deformity, most multiple-ligament knee injuries spontane-
Though less common, injury to the popliteal vein may ously reduce. One must have a high index of suspicion for
also occur with multi-ligament knee injuries. Richter re- these injuries. The patient's history provides essential in-
ported 10 ruptures of the popliteal vein in 89 patients with formation regarding the mechanism of injury and poten-
knee dislocations, compared with 8 arterial ruptures. 1° tial associated injuries. The direction of the force to the
These injuries can present with lower extremity edema, knee and the position of the leg are important variables.
venous stasis changes, thrombophlibitis, and even death Contact versus noncontact is worth documenting. A high-
from a pulmonary embolism. Even though these injuries energy motor vehicle accident is important to differentiate
are rare, they must be evaluated because of their devas- from a sports-related dislocation, because of the usual
tating consequences if missed. severe soft-tissue injury and associated injuries. 5,6
After obtaining the history, a thorough physical exam-
ination is performed. Examination of the entire extremity
NERVE INJURIES is critical. A visual inspection should note any obvious
The incidence of nerve injuries with knee dislocations is deformity or wound, as well as any subtle changes in skin
between 16% and 40%J -3 The peroneal nerve is most com- discoloration. The presence of a dimple sign or tight com-
monly injured, but injuries to the tibial nerve have oc- partments should also be assessed. A detailed neurovas-
curredJ l Injuries to the lateral and posterolateral corner of cular examination follows the visual inspection. The dor-
the knee place the peroneal nerve at increased risk, be- salis pedis and posterior tibialis pulses are palpated.
cause of its superficial location as it curves around the Never assume that a decreased pulse is normal and the
fibular head. Posterior dislocations have a high incidence result of spasm. Ankle brachial indices are assessed; a
of nerve injuries. The prognosis of peroneal nerve injuries decrease of 0.15 or greater indicates a significant vascular
is poor. Complete nerve injuries only recover about 50% of injury, s The patient is also asked to actively dorsiflex his or
the time. Nerve injuries are generally followed conserva- her foot and to activate the extensor hallicis longus tendon.
tively for 3 months. Of these injuries, about one third will These specific tests assess the peroneal nerve function.
recover, one third will have minor deficits, and one third Sensation in all of the nerve distributions, as well as motor
will have a complete palsy. 2 function of the tibial nerve should be examined.
A knee that presents still dislocated should undergo an
expedient examination so that an immediate reduction can
OTHER PATHOLOGY be obtained. Immediate reduction is performed with the
application of longitudinal traction, and this can be facil-
Open dislocations may occur with 19% to 35% of high- itated by the use of sedatives and analgesics. The presence
energy dislocations. 12,~3 The highest incidence of open in- of a dimple sign suggests that an open reduction may be
juries is seen in anterior and posterior dislocations. Cole necessary. After a reduction is achieved, a repeat neuro-
and Harner report injuries to the patella tendon or biceps vascular examination is necessarv. It is important to doc-
femoris in 20% of these patients. Fractures of the tibia ument all examination finding before and after reduction.
plateau occur in at least 10% to 20% of high-energy knee An examination of the mjured ligaments may be per-
dislocations. 7 The other pathology must be addressed in formed after reduction. The presence of sedation and an-
the treatment approach to these injuries. algesia will allow the stability examination to be per-
formed. Testing varus and valgus in full extension may
often illicit positive findings in a multiple-ligament-in-
EMERGENT SURGICAL CONDITIONS
jured knee. Opening to varus or valgus stress in full ex-
Vascular injuries, open dislocations, irreducible disloca- tension suggests that one or both of the cruciates as well as
tions, and compartment syndromes require prompt diag- a collateral ligament a n d / o r capsule has been disrupted.
nosis and immediate treatment. Vascular emergencies It is important to distinguish between a stable and un-
have already been discussed. Open dislocations must be stable knee injury. Stability is judged on the ability of the
reduced with subsequent irrigation and debridement in knee to remain in a reduced position. A stable knee may be
the operating room, and be treated with intravenous an- immobilized in extension, whereas an unstable knee must
tibiotics for 48 hours. Soft-tissue wounds should be eval- be placed in an external fixator in the operating room.
uated for problems with closure, as plastic surgery con- Postreduction radiographs must be obtained, and the knee
sultation is sometimes necessary. Lateral knee dislocations will need to be followed clinically and with radiographs to
may present as an irreducible dislocation. The medial assure that reduction is maintained.
femoral condyle may become buttonholed through the After manual or spontaneous reduction of the disloca-
medial retinaculum and present with the dimple sign. TM tion, a period of observation is appropriate to watch for
This particular type of dislocation may require open re- any delayed vascular changes. We prefer to admit the
duction. Prolonged dislocation in this position may cause patient overnight to the hospital. Because of the high

EVALUATING ACUTE MULTIPLE-LIGAMENT-INJURED KNEE 189


incidence of vascular injuries, an arterial injury should be assessment should be obtained. Gross instability to varus
assumed until proven otherwise. Signs of obvious vascu- and valgus testing in extension suggests injury to one or
lar injury, such as pulselessness, coolness, and pallor, re- both cruciate ligaments, the joint capsule, and the collat-
quire immediate consultation with a vascular surgeon. If eral ligaments. If the joint capsule has been disrupted, then
gross signs are not present, then serial exams may be there may not be an effusion. Flexion is often not possible.
performed. This precludes anterior and posterior drawer testing. The
The decision to get routine arteriograms on patients information obtained from the physical examination
with a knee dislocation in the presence of a normal exam- should be correlated with the history and mechanism of
ination is controversial. Many surgeons will argue that the injury.
presence of a normal examination does not rule out an The four main ligamentous structures include the ante-
occult or intimal tear. An intimal tear may clinically rior cruciate ligament, posterior cruciate ligament, medial
present on a delayed basis. 15,16 Although an arteriogram collateral ligament (MCL) with the posteromedial capsule,
procedure is not without complications, most surgeons and the posterolateral corner (PLC). The PLC is composed
agree that the complications of a missed arterial injury are of the lateral collateral ligament, popliteus tendon, popli-
more severe and outweigh the potential complications of teofibular ligament, arcuate ligament, fabellofibular liga-
the diagnostic procedure. Fanelli and Feldman recom- ment, and the posterolateral joint capsule. It is important
mend arteriography in patients with acute three-ligament- to specifically examine each of the 4 elements carefully.
injured knees to rule out vascular damage, especially in- The MRI should not be relied on solely, because the accu-
timal tears. 17 Several studies have shown that serial exam- racy of the test is diminished without clinical correlation.
inations are an effective method of ruling out a significant
arterial injury. Arteriogram studies have shown a rela-
ACL
tively low incidence of arterial injury from knee disloca-
tions associated with normal examsJ s-20 Dennis reported The ACL serves as the primary restraint to anterior trans-
that a physical examination predicted the need for vascu- lation of the tibia in relation to the femur. It provides 86%
lar surgery with 100% accuracy. The 7 minimal arterial of the resistance to anterior translation. 22 The ACL also
lesions found by arteriography in the 36 patients with a serves as a secondary stabilizer to varus, valgus, and ro-
normal examination were treated nonoperatively.21 tational stresses about the knee. 23 The most reliable and
Treiman also reported the distal pulse examination to be sensitive test for assessing ACL deficiency is the Lachman
100% accurate for identifying patients who will need vas- test. In multiple-ligament-injured knees, this test is more
cular surgery. This study found the physical examination difficult to perform. For example, PCL-deficient knees can
to be 85% sensitive at diagnosing an arterial injury. 2° At mislead the examiner because of the abnormal translation.
our institution, all patients with a knee dislocation are Also, a complete MCL disruption can give a false-positive
admitted for observation and serial examinations, with Lachman test if care is not taken to perform the test in
particular attention to the neurovascular assessment. A internal rotation. This results from the anteromedial rota-
vascular surgery consultation is obtained as well to pre- tional instability secondary to MCL disruption.
vent any delay in the treatment of a vascular injury should
one develop on a delayed basis. The initial evaluation
PCL
follows the basic steps of a treatment algorithm (Fig 1).
After the initial assessment of the knee dislocation, an- The PCL serves as the primary restraint to posterior trans-
terior/posterior and lateral radiographs are obtained. The lation of the tibia. 22 The physical examination of the PCL
knee joint is evaluated for associated fractures and the includes the posterior drawer test, posterior sag sign,
adequacy of the reduction. Reduction should not be de- quadriceps active test, and Godfrey's test. The most sen-
layed for radiographs. Other views include intercondylar sitive test is the posterior drawer test. The anterior tibial-
notch and patellofemoral radiographs. These images as- femoral step-off is important to note when performing this
sess the extensor mechanism, and may visualize possible test. Normal step-off is 8 to 10 mm (tibia anterior to the
ligament avulsion fractures. Magnetic resonance imaging femur with the knee flexed 90°). This test is graded ac-
(MRI) is necessary to evaluate the ligamentous structures cording to the amount of translation with a posterior
and other soft tissues. It may help diagnose a patella directed force.
tendon or quadriceps rupture; in these injuries, an early
repair is indicated. An MRI may also identify meniscus
MCL
injuries, cartilage lesions, bone bruises, and occult frac-
tures. The information obtained by these studies is useful The MCL is the primary restraint to a valgus knee stress at
in preoperative planning. We recommend obtaining an 20 ° to 30 ° flexion. It is also a secondary restraint to anterior
MRI in all cases in which a repair, reconstruction, or both translation. Testing is performed by applying a vagus
is planned. This imaging study can be obtained in a non- stress at 20 ° to 30 ° flexion. This test is graded according to
emergent fashion. the amount of joint line opening in millimeters and the
presence of an endpoint. The knee is also tested in full
extension. Opening to valgus testing in full extension im-
EXAMINATION OF SPECIFIC LIGAMENTOUS plies damage to the posteromedial capsule in addition to
STRUCTURES the superficial MCL.24 The posteromedial capsule is part of
In the acute setting, swelling and pain often prevent a the deep MCL, and it may need to be repaired or recon-
detailed ligament examination. However, the best possible structed in certain cases.

190 WILSON AND JOHNSON


Multiple-Ligament Knee Injuries
Open Skin "Dimple Sign" Skin Intact

Reduction ~ No Reduction Reduction

To OR Immediately To OR Immediately Physical Exam

Irrigation Open Reduction Pulses Present Pulses Absent

Unstable Stable PE for Stability Vascular Consult

Ex-Fix B~ace Stable Unstable OR/Arteriogram


Fig 1. Treatment algorithm
for multiple-ligament knee
injuries. IV Antibiotics Immobilize To OR NL Injury

Observe X-ray Reduction Reduction Repair

Reduced Unreduced Ex-Fix Stable Unstable Ex-Fix


"a
Observe To OR Observe Immobilize Ex-Fix Observe

Reduce Observe Observe

Ex-Fix

+
Observe

PLC a n d treat an injury of the PLC of the knee in a patient w h o


has a tear of the ACL or PCL can result in failure of the
The PLC resists v a r u s a n d rotational forces to the knee.
reconstructed ligament.
The a n a t o m i c structures of the PLC can be d i v i d e d into 3
layers. L a y e r 1 is c o m p o s e d of the iliotibial b a n d a n d the
biceps femoris tendon. L a y e r 2 consists of the lateral reti-
CONCLUSIONS
n a c u l u m a n d lateral patellofemoral ligaments. Layer 3 is
the d e e p e s t a n d contains the lateral collateral l i g a m e n t or The initial diagnosis of a knee dislocation or multiple-
fibular collateral ligament, the fabellofibular ligament, the l i g a m e n t knee injury is an orthopaedic emergency. A vas-
popliteus, the arcuate complex, a n d the i m p o r t a n t poplit- cular injury m u s t be a s s u m e d until it can be ruled out. A
eofibular ligament. Testing of the PLC consists of v a r u s t h o r o u g h n e u r o v a s c u l a r e x a m i n a t i o n should be per-
stressing the knee at 0 ° a n d 30 °. Increased external rotation f o r m e d before a n d after reduction of the knee joint. These
of the tibia at 30 ° a n d 90 ° is tested a n d c o m p a r e d w i t h the patients should then be o b s e r v e d for a n y changes in their
contralateral knee. O t h e r tests include the posterolateral vascular examination. All patients w i t h a p e r f u s e d extrem-
d r a w e r test, external rotation d r a w e r test, a n d reverse ity b u t a b n o r m a l vascular status should u n d e r g o an arte-
p i v o t shift test. Increased o p e n i n g to v a r u s stress at 30 ° riogram. Patients w i t h o u t pulses or a n o n p e r f u s e d extrem-
w i t h o u t o p e n i n g at 0 ° or other signs of a PLC injury ity should go i m m e d i a t e l y to the operating r o o m w i t h a
suggests an isolated tear of the FCL. 25 Failure to diagnose vascular s u r g e o n w h o can p e r f o r m an on-the-table anglo-

EVALUATING ACUTE MULTIPLE-LIGAMENT-INJURED KNEE 191


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192 WILSON AND JOHNSON

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