Nano Silver

Neena Sahasrabudhe DTSC

Nano Material Applications

CONSUMER PRODUCTS PESTICIDES AND ANTIMICROBIALS MEDICAL DIAGNOSTICS AND PHARMACEUTICALS BIOTECHNOLOGY AUTOMOTIVE PAINTS AND COATINGS COSMETICS AND PERSONAL CARE ENERGY AND ELECTRONICS WATER AND WASTE TREATMENT
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Nano silver uses

Medical Productswound dressings,
surgical gauze, bandages

Textiles and Clothing Sporting Goods Aerospace and Electronics

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Why are nano materials popular?

Different Physical and Chemical

properties

Anti-bacterial and anti-fungal properties Light weight Enhanced product performance

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Nano materials also used in

Environmental Remediation Decontamination of Pollutants

Environmental Health and Safety Concerns of Nano Silver

Potential to be released into environment May be toxic to beneficial microbes Impact on aquatic species
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Nano Material Lifecycle

Processes Integration Systems Devices

Manufacture

Materials

Transportation

Storage

Facility Consumer Products

Release Disposal

Waste

Workers

Consumers / Public Air

Food

Ocean

Water

Soil/ Sediment Plant Animal

Environment

I-on concern
Ag (metal) Ag
+

e-

Silver ions (Ag+) were considered the culprit behind the toxicity of silver nano particles (AgNP*) * AgNP- Silver nano particles
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Wastewater treatment concerns

Considering the current extensive production of Ag NPs and their widespread use in consumer products, it is likely that they are entering wastewater streams and the treatment facilities that process this water**

nano silver in products can affect the good bacteria in treatment plants Treatment plants may not function to its capacity **Discovery and Characterization of Silver Sulfide Nanoparticles in Final Sewage Sludge Products
Kim , Park, Murayama and Hochella, The Center for NanoBioEarth, Department of Geosciences,Virginia Tech, Department of Materials Science and Engineering

From consumer uses

May affect solids treatment and energy processes?

May affect treatment process?

May affect receiving water and biota?

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Other Concerns
Other consumer products lined with antibacterial nano silver Food containers, baby bottles Band aids Medicinal supplements

FDA nanotechnology section

DTSC does not cover all consumer products

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Is human population affected?

Silver metal in colloidal form has been used as

anti-bacterial from ancient times Engineered nano silver differs from silver metal Definitive research on nano silver and in vivo studies for mammals is unknown Research at UCLA plans to find out IF silver nano plates are toxic to mammalian lungs if inhaled
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What we know and do not know

manufacturer

Nano material obtained by the Manufacturer may know the modification

of nanomaterial into the product environment IS UNKNOWN

What is coming out of product into the

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Data gaps
Fate, Transport, Toxicity and ANALYTICAL METHODS unknown

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Nano Silver in Environment

Lake Ecosystem Nano Silver ( LENS) Project* Effect of nano silver on aquatic environment Will monitor changes in lakes ecosystem Track effects through entire food web Determine how resulting changes alter ecosystem function * Trent University- Natural Sciences and Engineering Research Council of Canada, Environmental Canada Support- Fisheries and Oceans Canada
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Measurement Techniques
Transmission Electron Microscopy (TEM) Scanning Electron Microscopy (SEM) X- Ray Diffraction (XRD) Atomic Force Microscopy (AFM) Measurement*** of silver nano particles also depends on Agglomeration/ thickness of initial capping agents Dispersion conditions/thickness of natural organic molecules (NOM)
***Challenges for physical characterization of silver nano particles under pristine and environmentally relevant conditions Robert Mac Cuspie et al, J. Environ. Monit.,2011

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Shape affects Toxicity

Silver nano plates are toxic in direct contact with cells of some fish* Silver nano spheres are toxic in high concentration Silver nano wires are much less toxic
* Rainbow Trout and Zebra fish** ** nanotechweb- research at UCLA, DR.A. Nel, S. George et al 17

Round Two call-in dataset identified: Twelve (12) nano silver manufacturers or importers Requested information from manufacturers and importers on analytical methods of their chemical

DTSC and Nanosilver

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1.Cooperation and communications with creators and user's of the material 2.MOU with other state agency (DPR*) 3. Collaboration with Federal agencies, Universities, research agencies 4. Other participations 5. Nano toolkit
*DPR- Department of Pesticide Regulations( Cal EPA)
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Outcomes

Thank you
Neena Sahasrabudhe, Ph.D. 916/324 8660 nsahasra@dtsc.ca.gov

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