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An Overview of Hemoglobin
This brief overview of hemoglobin is not meant to be comprehensive. The goal is to provide sufficient background to make this Web site useful to people unfamiliar with the area. More detailed sources are listed at the end of this file.
A.) What is hemoglobin?
Hemoglobin is a protein that is carried by red cells. It picks up oxygen in the lungs and delivers it to the peripheral tissues to maintain the viability of cells. Hemoglobin is made from two similar proteins that "stick together". Both proteins must be present for the hemoglobin to pick up and release oxygen normally. One of the component proteins is called alpha, the other is beta. Before birth, the beta protein is not expressed. A hemoglobin protein found only during fetal development, called gamma, substitutes up until birth.
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Harrison's Principles of Internal Medicine, McGraw-Hill The Principles and Practice of Medicine, Appleton, Century, Croftis "Hemoglobin: molecular, genetic, and clinical aspects", HF Bunn and B Forget, Saunders, 1986.
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