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DRUG STUDY Name of Drug Generic Name: Bumetanide Brand Name: Burinex Dose: 1 mg Frequency: q12 Route: IV

Classification and Mechanismm of Action

Indications -Edema associated with heart failure, hepatic and renal disease

Side Effects -CNS: asterixis, dizziness, weakness, headache, drowsiness -CV: osthostatic hypotension -GI: nausea, anorexia, vomiting, diarrhea -GU: polyuria, nocturia -Hematologic: hypokalemia, leukopenia, anemia

Contraindications -Contraindicated with allergy to bumetanide or sulphonamides; electrolyte depletion; anuria; severe renal failure and hepatic coma -Use cautiously with gout and diabetes mellitus

Nursing Responsibilities -Assess vital signs before giving medication -Take the meds with food or meals to prevent GI upset -Give the drug early in day so increase urination will not disturb sleep -Provide diet rich in potassium or supplemental potassium -Avoid use if oral use is possible -Instruct patient they may experience increase volume and frequency of urination

Monitoring Parameters -Monitor serum electrolytes, hydration and hepatic function during long term therapy -Monitor weight of the patient

-Loop Diuretic -Inhibits the reabsorption of sodium and chloride from the proximal and distal renal tubules and the loop of Henle, leading to a natriuretic diuresis.

Name of Drug Generic Name: Insulin Brand Name: Lantus Dose: 6 u @ 8pm Route: Subcutaneous

Classification and Mechanismm of Action

Indications -Treatment of adults patient with type 2 diabetes mellitus who require basal insulin control of hyperglycemia

Side Effects -allergy local reactions at injection site -Metabolic: hypoglycaemia, ketoacidosis

Contraindications -Contraindicated with allergy to pork products, history of smoking or lung disease -Use cautiously with gout and diabetes mellitus

Nursing Responsibilities -Assess vital signs before giving medication -use same type of syringe; same type and brand of insulin to avoid dosage error -Rotate injection site regularly to prevent breakdown at injection sites -Store drug in the refrigerator or in a cool place out of direct sunlight -Avoid alcohol; serious reaction can occur -Report fever, vomiting, hypoglycemic or hyperglycemic reactions, rash

Monitoring Parameters -Monitor urine or blood levels for glucose and ketones as prescribed -Monitor injection site regularly

-Antidiabetic -Hormone -Insulin is a hormone secreted by beta cells of the pancreas that, by receptor mediated effects, promote the storage of the bodys fuels, facilitating the transport of metabolites and ions through cell membranes and stimulating the synthesis of glycogen from glucose, of fats from lipids and proteins from amino acids..