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Ans : Donor O-Blood Group Recepient : AB+ blood group Q2:Which condition is produced in Rh+ blood group in a fetus mother having Rh- blood group in second pregnancy? Ans:Erythroblastosis foetalis Q3:identify the apparatus? Ans: Wester Green Apparatus Q4:Name the two physiological conditions in which ESR is hIgh? Ans: a) Pregnancy b) Mensturation c)Increased temp. Q5:Identify the apparastus? Ans: Westergens Tube with stand Q6:Give one cause of Microcytic anemia? Ans:Deficiency of Vit B12 ( folic acid) Q7:Write down contents of Haemy`s fluid? Ans: Disteled water Nacl Q8: Name the areas in the body where reproduction of RBCs take place? Ans : Yolk sac,liver . spleen, lymph node,bone marrow Q9: Identify the apparatus? Ans: Syphmomanaometer Q10: What is the effect of moderate exercise on systolic blood ptressure? Ans: Systolic blood pressure increases
Q11: Which nervous mechanism increases blood pressure during exercise? Ans: Symptahtic over stimulation Q12:Enumerate two methods of recording blood pressure? Ans:Auscaltatory method Palpatory method Q13: What is rouleax formation? Ans:Pilling up of cells one upon another because their density is more than plasma is called rouleax formation Q14:Name two pathological conditions in which ESR is raised? Ans: Acute Infections: Choronic infections Malignancy Q15: Name the two conditions in which Leucocytes count increases Ans : Appendicitis , Tonsilitis , Pnemonia Q16: What is the mean corpuscular Hb concentration? Ans:It is the average Hb conc. Inerthyrocytes MCHC=Hb gram/100ml PCV/100ml * 100
Q17:What is the clinical significance of MCHC? Ans:If MCHC less than 32, the RBC is hypochromic and it is present in iron deficiency anemia and thalasemia Q18: What is FEVI % Ans: It is the percentage of vital capacity which is expired in fst second of expiration Q19: In what type of disese it is increased? Ans: It is increased in Obstructive Lung Disease . Q20: What produces 1st heart sound? Ans: Closure of Mitral and Tricuspid valves line in less 5th intercostals space
Q21: In which area apex beat is examined ? Ans : About 9 cm from midline or 1 cm internal to midclavical . Q22: Name the conditions In which clotting time is increased ? Ans: Haemophilia A , B,Vit deficiency and liver disease and Throbocytopenia Q23: What is normal clotting time? Ans:2-6 mins capillary method Q24: How will you charge Neubaurs Chamber? Ans: a) Clean the Neubaur Chamber B)Fix the Nuebar chamber on the stage with clips and place coverslip over it c)Now take the prepared RBC/WBC pipette and touch the tip of the pipette near the edge coverslip on central plat form at an angle of 45 degrees and drop wise drop the fluid d)The fluid enters the below the coverslip because the capillary action immediately removes the pipette Q25:Write the contents of Haeym`s fluid? Ans : NaCl Na2SO4 Hgcl2 Distilled Water Q26: Prepare the blood smear on a slide for DLC count. Q27:Name the conditions in which the neutrophils are increased ? Ans: Acute pyrogenic infections ,Abscess,Boils and tonsilits Q28: Write two functions of platelets ? Ans:Haemostasis Coagulation and Clot retraction
Q29: why the Leshman stain be acetone free? Ans: Acetone causes shrinkage of cells and may cause lysis of cells Q30: what type of image do you observe in the microscope ? Ans : Eye Piece forms vertical ,erect and enlarged image. Q31: name the antigen on RBC and agglutinin in the plasma of patient with O blood group? Ans: Antigen .>None , Agglutinin ..> Anti A and Anti B
Q32:What is the genotype and phenotype of the above patient? Ans: Phenotype O , Genotype OO Q33:How will you charge the Westergen Tube? Q34:Give any two physiological conditions in which ESR is raised? Ans: Pregnancy , Menstruration , Increased Temp and High in females Q35: Why and how many times the blood is diluted to count red blood cells ? Ans: The No of RBCs is very high so blood is diluted 200 times with diluents Q36: Give two pathological factors causing polycythemia? Ans: Hypoxia , polycythemia vera
Term
Definition
water
Water makes up ___ to ____% of body weight at birth and ____ to ____% at maturity.
Term Definition
Percentage of body water (decreases/increases) with age and has an inverse relationship with body _____.
Term Definition
decreases, fat
90, 95
2
Term Definition
transportation of nutrients and secretions chemical reactions and solvent properties body temparature regulation maintain shape of body cells lubricates and cushions joints and organs in the body cavity
Term
Definition
Term
Definition
4
Term Definition
4
Term Definition
4
Term Definition
Extracellur water makes up ___ of total body water or ___% of body weight.
Term Definition
1/3, 20
Term
Definition
the fluid in between the cells and in reality is the cells' environment
Definition
Term
15
Term
92, 8
Term
What is the percent of intracellular body water in some animals versus in ruminant animals?
Term
it is relatively small but in ruminant animals it can be quite a large amount because of their increased gut volume
Definition
Intracellular water makes up ___ of body water and ___% of body weight.
Term Definition
2/3, 40
Term
Definition
Term
Definition
transportation of dissolved gases, nutrients, hormones, and metabolic wastes regulation of the pH and electrlyte composition of interstitial fluids throughout the body restriction of fluid losses (in event of injury) defense against toxins and
pathogens
Term
Definition
8-10%
What is the viscocity of blood compared it is five times more viscous than water to water?
Term Definition
7.35-7.45
Term
erythrocytes
leucocytes
thrombocytes
Definition
granulocytes?
Term Definition
45-65%
92%
7%
1%
Definition
35-55%
99.9%
10
Term Definition
the blood is allowed to clot it is put in a centrifuge serum is separated from the clotted blood
Term
Definition
Term
If you want to separate blood into three parts in order to get plasma, what must you use?
Term
Definition
When blood is spun in a centrifuge, what is the order in which the blood separates starting at the top?
Term
Definition
the most abundant plasma protein; transports lipids and steroid hormones
Definition
the liver
antibodies
Definition
Term
plasma proteins
colloid plasma proteins maintain higher concentrations and form osmotic pressure, preventing loss of plasma from the bloodand maintaining volume (the presence of plasma proteins in the blood causes water to enter the blood vessels and helps maintain blood volume)
Definition
Term
oncotic pressure
it controls pH
60%
many substances with low water solubility, such as bile salts, fatty acids, calcium, iron, and some drugs
Definition
Term
Term
Term
Term
What type of molecule carries energy lipids and structural lipids for biosynthesis?
Term Definition
lipoprotein complexes
What is HDL?
Term Definition
because they are mostly protein and only have some phospholipids so they have a high density
Definition
Term
because they have only a little protein and have more phospholipids so they have a low density
Definition
Term
because they have the most phospholipids and have little protein so they ahve a very low density
Definition
Term
17
Term Definition
17
Term Definition
Term
Term
Definition
110 days
What structure destroys old erythrocytes and where in the body do they destroy them?
Term Definition
macrophages, in spleen
bone marrow
erythropoieisis
the kidneys monitor the blood and if there are nor enough it sends an endocrine signal to the bone marrow to produce more
Definition
Term
What is the hormone that the kidney secretes to tell the bone marrow to produce more RBCs?
Term Definition
erythropoietin
What is the specific process that occurs when the kidneys decide that there is not enough RBCs?
the kidneys detect reduced O2 carrying capacity when less O2 is delivered to the
kidneys, they secrete the hormone erythropoietin erythropoietin stimulates erythropoiesis by the bone marrow the additional circulating erythrocytes increase the O2 carrying capacity of the blood this relieves the initial stimulus that triggered erythropoieten secretion
Term
Definition
hemoglobin
iron, hemoglobin
Term
What is hemoglobin?
Term
Definition
reversibly
1, 4
nuclei, organelles
Term
transportation
WBCs are capable of ________ amoeboid; this allows them to converge movement. What is the purpose of this? on pathogens and sites of injury
Term Definition
What is diapedesis?
the process by which WBCs migrate out of the blood stream by squeezing between endothelial cells
Definition
Term
neutrophils eosinophils
Term
Definition
50, 70
Definition
What is the nucleus of mature neutrophils like? Because of this, neutrophils are known as _________ leukocytes.
Term
segmented; polymorphonuclear
Definition
12 m
they are highly mobile and are usually the first WBCs to arrive at a site of injury
Definition
Term
attacking and digesting bacteria that have been marked for destruction
Definition
Term
2,4
Definition
they phagocytize antibody covered bacteria, protazoa, and cellular debris they exocytose toxic compounds onto the surface of pathogens, particularly large multicelluar parasites such as flukes or worms
Term
Definition
Definition
they are sentive to allergens and dramatically increase in number during allergic reactions
Definition
Term
8-12 days
less than 1
Term
granules
Term
Definition
Term
an anticoagulant
they enhance the local inflammation initiated by mast cells and attract other WBCs
Definition
Term
it is uncertain
2,8
2X as large as a RBC
What is the nucleus of a monocyte like? it is large and tends to be oval or kidney shaped
Term Definition
individual monocytes use the bloodstream as a highway they stay in circulation for only about 24hrs before entering a peripheral tissue where it becomes a tissue macrophage, an aggressive phagocyte
Term
Definition
normal: replenish resident macrophages and dendritic cells inflammation signals: move quickly (approximately 8-12 hours) to sites of infection in the tissuesand divide/differentiate into macrophages and dendritic cells to elicit an immune response
Term
Definition
20, 30
What is the structure of lymphocytes as there is a thin halo of cytoplasm around seen in blood smears? a large nucleus
Term Definition
they continuosly migrate from the bloodstream back into the peripheral tissues and back into the bloodstream
Definition
Term
Term
T and B lymphocytes
they defend against foreign cells and tissues and coordinate the immune response
Term
Definition
killer T cells
days to years
How can you remember all the lymphocytes and their order of abundance?
Term
Never Let Monkeys Eat Bananas: neutrophils, lymphocytes, monocytes, eosinophils, and basophils
Definition
9-12 days, they are then removed by spleen macrophages, they are continuosly replaced
Definition
Term
Definition
bone marrow; large cells called megakaryocytesrelease fragments (platelets) into circulation
Definition
Term
thrombopoiesis
Term
Definition
What is homeopoiesis?
Term
35
Term Definition
What is hemostasis?
Term
36
Term Definition
36
Term Definition
vascular phase (vascular spasm) platelet phase (formation of platelet plug) coagulating phase (blood clot formation)
Term
Definition
Term
Definition
platelets attach to sticky area platelet plug is formed chemicals released to attract more pletelets
Term
Definition
Term
Definition
The clot contains _______ and _______ which constrict the clot.
Term Definition
actin, myosin
clot is dissolved by fibrinolysis plasmin (active form of plasminogen) erodes the clot
Term
Definition
What is thrombus?
(blood clot) it is when platelets stick to the interior of an intact blood vessel
Definition
Term
What is embolus?
Term
Definition
embolus