@UrologyQuiz Quiz1 Follow-up MCQs: (ANSWERS BELOW!) 1.

This describes pathological T3a staging of renal cell carcinoma: A) Perirenal &/or renal sinus (peripelvic) fat, extends into the vena cava below diaphragm B) Tumour grossly extends into the renal vein or its segmental (muscle-containing) branches C) Direct extension into the adrenal gland D) Tumor size greater than 10cm

2. The prognosis of T3 renal cell carcinoma A) is independent of tumor subtype B) is similar for all T3 patients C) is similar to direct invasion of the adrenal gland D) is not dependent on level of renal vein/vena caval invasion

3. This describes pathological T2 staging of renal cell carcinoma: A) T2c Tumour >10 cm not limited to kidney but just beyond capsule not into fat B) T2a Tumour > 7 cm in greatest dimension but < 10cm C) T2b Tumours > 10 cm limited to kidney D) T2a Tumour 7 cm in greatest dimension but 10cm ANSWERS Q1 Answer A: 2010 AJCC TNM - T3=Tumour extends into major veins or perinephric tissues, but not into the ipsilateral adrenal gland and not beyond Gerotas fascia; B,C,D incorrect see below T3a Tumour grossly extends into the renal vein or its segmental (muscle-containing) branches, or tumour invades perirenal &/or renal sinus (peripelvic) fat but not beyond Gerotas fascia T3b Tumour grossly extends into the vena cava below diaphragm T3c Tumour grossly extends into vena cava or its wall above the diaphragm or invades the wall of the vena cava Q2 Answer D: Surprisingly, there has been little to no correlation for the level of the IVC tumour thrombus and Overall Survival [http://uffer.org/downloads/publications/2012_PeerReviewed_Publications/9-Renal_Cell_Carcinoma.pdf]. A-subtype always important; B-no, see Quiz1 Answer; C-this T4 disease, by definition worse prognosis Q3 Answer C: 2010 AJCC TNM T2=Tumour > 7 cm in greatest dimension, limited to the kidney T2a Tumour > 7 cm in greatest dimension but 10cm T2b Tumours > 10 cm limited to the kidney