SCHOOL OF NATURAL SCIENCES General Luna Road, Baguio City

UB VISION In pursuit of perfection, the University of Baguio is committed to provide balanced quality education by nurturing academic excellence, relevant social skills and ethical values in a fun-learning environment. UB MISSION The University of Baguio educates individuals to be empowered professionals in a global community. INSTITUTIONAL OBJECTIVES (REVISED 2012) The University of Baguio aims to produce a graduate who: 1. exemplifies a higher standard of learning; 2. manifests the mastery of relevant skills; 3. upholds a conduct that is rightful and just; 4. undertakes scientific and significant researches; 5. advocates sustainable programs for the community and the environment; and 6. leads and demonstrates exemplary performance in the field of specialization.

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

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SCHOOL OF NATURAL SCIENCES General Luna Road, Baguio City

SCHOOL MISSION The University of Baguio educates individuals to be empowered professionals in a global community. The School of Natural Sciences is a dynamic and value-oriented community committed to the advancement of the modern health care system. SCHOOL OBJECTIVES (REVISED 2012) The School of Natural Sciences is an environment conducive to learning which aims to produce a graduate who: 1. performs exemplary allied health medical services; 2. competes globally in delivering advanced health care services; 3. adapts a strong sense of social responsibility and accountability in a diverse culture; 4. undertakes relevant scientific researches for community advancement; 5. advocates noble ecological practices for a healthy environment; and 6. supports and sustains quality of work in the attainment of total wellness.

PROGRAM OBJECTIVES (REVISED 2012) The BMLS program aims to produce a graduate who: 1. carries out precise clinical laboratory work; 2. demonstrates competence required of a clinical laboratory professional; 3. leads in upholding the integrity of the profession; 4. conducts researches on health and other allied disciplines; 5. promotes a healthy environment through clean and green programs; and 6. ensures quality performance in laboratory science.

CORE VALUES 1. 2. 3. 4. 5.

Service-Oriented Emotional Maturity Client Sensitivity Accountability Credibility

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

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1. Program Learning Outcomes vis a vis Program Objectives Program Learning Outcomes (CMO 14 series 2006; Art IV section 5) Graduates of Bachelor of Science in Medical Technology/Bachelor in Medical Laboratory Science like any other Health Professions Education must be able to apply analytical and critical thinking in clinical laboratory. As such, graduates abovementioned must: 01. collect samples, prepare specimen for analysis, determine the acceptability of samples within guidelines, perform the test according to standard methods/techniques; 02. demonstrate skills in judgment and decision making to analyze quality control and recognize implausible results and take appropriate actions to maintain accuracy and precision; 03. perform accurately data gathering, processing and encoding into the computer system; 04. observe the principles of data security or patient confidentiality, maintain ethical standards in working with other laboratory and hospital personnel; 05. possess good communication and human relation skills for effective and healthy interaction with health care professionals; 06. take responsibility for their own professional development or continuing education especially computer education in the application and management of data and computerized laboratory equipment; and, 07. acquire basic management, supervision, administrative skills to contribute to the resolution of conflicts pertaining to laboratory management, implementation of changes in response to technology and laboratory procedures, development of safety management procedures and improvement of standards of practice. PROGRAM OBJECTIVES P1 P2 P3 P4 P5 P6

2. Course Objectives vis a vis Program Outcomes PROGRAM OUTCOMES 01 02 03 04 05 06 07

Course Objectives Cognitive: At the end of the course the students should: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Identify the different parts and the chemical components of a cell. 6. Define terms associated with CHO; 7. Describe CHO according to composition, classification and chemical properties;
Course Number: BIOCHM2 (5 units: 3u lec and 2u lab) Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 3 of 16

8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21.

Discuss the metabolism of CHO in the body; Explain the mode of actions of different hormones in the maintenance of blood glucose levels; Discuss the different processes involved in the maintenance of normal blood glucose; Classify proteins according to structure and function; Discuss the digestion of complex biomolecules in the body; Discuss the metabolism of amino nitrogen; Illustrate the structures of the different amino acids; Describe the metabolism of the different amino acids; Describe terms associated with lipids; Describe lipids according to composition, classification, properties; Discuss the metabolism of lipids in the body; Describe the nature of enzymes; Comprehend how enzyme kinetics occur; Identify the different factors that will influence an enzymatic reaction;

Affective: At the end of the course the students should: 1. Discern the importance of the knowledge of metabolism in keeping oneself healthy; 2. Appreciate the significance of the metabolism of different biomolecules in the maintenance of normal life processes; 3. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 4. 5. Internalize the relationship that exists among the different metabolic pathways; Develop a persevering attitude in studying intricate metabolic processes;

1.

Psychomotor: At the end of the course the students should: 1. Analyze results obtained from experiments to compare with biological concepts; 2. Sketch an illustration of a typical animal cell; 3. Perform skillfully the procedures included in the laboratory experiments; 4. 5. 6. 7. 8. 9. Apply the universal precautions; Discuss the different laboratory hazards; Demonstrate laboratory safety practices and proper waste disposal; Perform accurately the tests that will identify carbohydrates; Perform accurately the tests that will characterize proteins; Perform accurately the tests that will manifest the properties of lipids;

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 4 of 16

Course Description This course deals with the study of the chemical composition of living matter. It deals with the study of the structure and function of carbohydrates, lipids, proteins and amino acids. It also includes the different biochemical mechanisms involved in the breakdown of complex bio-molecules which lead to the synthesis of important metabolites and the production of energy. Emphasis is also given on the medical, clinical, and human implications from the concepts presented, so designed as to enable students to understand it and also to help students appreciate their importance in the chemical processes of the human body, to enable them to use these knowledge in their chosen fields of specialization Prerequisite: ORGCHM2/ORGCHL2 - Organic Chemistry Co-requisite/.s: None

I.

DETAILED COURSE OUTLINE: Outcomes Based Methodologies / Strategies & Approaches for Lecture Orientation Internalize the VMO Arrange students Requirements and Grading system 1. Interactive discussion 2. VCD Viewing 3. Virtual Reality Viewing 4. Picture and visual aid presentation 5. Simulation 2 hrs The student must have acquired an understanding of the basic concepts relating to biochemistry, particularly on biomolecules and an overview of metabolism. This is relatively important as the student has
Effectivity: 1st Semester, SY 2013-2014

Session Learning Objectives/Goals (SLO/G)

Content Topic

Time Allot ment

Outcomes Based Methodologies /Strategies & Approaches for Laboratory

Learning Outcomes

Time allot ment

Values

Evaluative Measures

PRC TOS

Course Syllabus VMO Seat Plan Leveling of Expectations

At the end of the course, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and

Unit 1: INTRODUCTION TO BIOCHEMISTRY 1.1. Definition, History and Importance 1.2. Branches of Biochemistry 1.2.1.Molecular Anatomy 1.2.2.Molecular Physiology

Serviceoriented Emotional maturity Accountabil ity

Each student must be able to attain 70% of the total scores in the following assessments: Recitation Written quiz Unit test Research / Homework

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Date Revised: May 29, 2013

Page 5 of 16

relate its importance in the clinical aspect of the course. 4. Discern the importance of the knowledge of metabolism in keeping oneself healthy; 5. Appreciate the significance of the metabolism of different biomolecules in the maintenance of normal life processes; 6. Obey protocols in the laboratory for the maintenance of a clean & safe working environment.

1.3. Molecular Anatomy: The Biomolecules 1.3.1. Carbohydrates 1.3.2. Lipids 1.3.3. Proteins 1.3.4. Nucleic acids 1.4. Molecular Physiology: Overview on Metabolism 1.4.1. Definition 1.4.2. Functions of Metabolism 1.4.3. Phases of Metabolism

learned to take responsibility for his own professional development or continuing education.

At the end of the course, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Identify the different parts and the chemical components of a cell. 3. Explain the physiological importance of the different bio-molecules. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; Sketch an illustration of a typical animal cell;

Unit 2: BIOCHEMISTRY OF THE CELL 2.1. Definition, History and the Cell Theory 2.2. Basic classification of Cells 2.2.1.Prokaryotes vs. Eukaryotes 2.2.2.Somatic cells vs. Sex cells 2.2.3.Animal cells vs. Plant cells 2.3. Chemical Composition and Functions of the Cell and its Organelles 2.3.1.Nucleus 2.3.2.Cytoplasm 2.3.3.Cell Membrane 2.3.4.Mitochondrion 2.3.5.Endoplasmic Reticulum

1. Interactive discussion 2. VCD Viewing 3. Virtual Reality Viewing 4. Picture and visual aid presentation 5. Utilization of model slides to be focused under the microscope 6. Drawing activity and Model construction 7. Simulation

5 hrs

Expt. No. 1: The Animal Cell - The students will examine and illustrate a typical animal cell.

The student must have acquired an understanding of the basic concepts relating to the cell, to include its structure and its bio-molecular components. These concepts shall serve as important foundation as the student has developed an attitude of being responsible for his own professional development or continuing education.

3 hrs

Serviceoriented Emotional maturity Accountabil ity

Each student must attain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written Assignments 3. Research Works 4. Practical Examinations 5. Unit/Topic Quizzes 6. Major Examinations

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 6 of 16

2.3.6.Golgi Apparatus 2.3.7.Ribosomes 2.3.8.Lysosomes 2.3.9.Peroxisomes 2.3.10. Cytoskeleton 2.4 NUCLEIC ACIDS AND HEREDITY 2.4.1 Definition, Importance and Functions of Nucleic Acids 2.4.2 Structural Components, Nomenclature and Features 2.4.3 Nucleoproteins 2.4.4 Nucleotides 2.4.5 Nucleosides 2.5 The DNA molecule 2.6 DNA Structure DNA Replication 2.7 The RNA molecule 2.7.1 RNA Structure 2.7.2 Types of RNA 2.8 The Genetic Code 2.9 Protein Synthesis 2.9.1 Transcription 2.9.2 Translation 2.10 Mutation and other Clinical Significances of Nucleic Acid Metabolism At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. Unit 3: COLLOIDAL STATE OF MATTER 3.1. Definition of Terms 3.2. Classification of Colloids 3.2.1.Emulsoids 3.2.2.Suspensoids 3.3. Properties of Colloids Lecture Interactive Discussion Power point presentations Individual reading assignments 1 hrs The students will actually perform the following activities and analyze the results obtained: Expt. No. 2: Colloids The student must have obtained an understanding of concepts relating to colloids, which provides a better characterization of cell function. These Serviceoriented Emotional maturity Accountabil ity 3 hrs Each student must obtain at least 70% of the total scores in the following assessments: Recitation Topic/Unit quiz
Page 7 of 16

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 6. Analyze results obtained from experiments to compare with biological concepts; 7. Perform skillfully the procedures included in the laboratory experiments; 8. Apply the universal precautions; 9. Discuss the different laboratory hazards; 10. Demonstrate laboratory safety practices and proper waste disposal; At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Describe the nature of enzymes; 3. Comprehend how enzyme kinetics occur; 4. Identify the different factors that will influence an

3.3.1.Physical Properties 3.3.2.Chemical Properties

with written report

Expt. No. 3: Protective Action of Colloids Expt. No. 4: Diffusion thru Gelatin Expt. No. 5: Dialysis Expt. No. 6 Adsorption Expt. No. 7: Behavior of RBC in diff. Osmotic Conc.

concepts shall serve as important foundation as the student has developed an attitude of being responsible for his own professional development or continuing education. In addition, the student must have acquired basic management, supervision, administrative skills to contribute to the development of safety management procedures and improvement of standards of practice.

3 hrs

Research / Homework Performance rating (based on accuracy, contribution to research & wearing of lab gown & ID)

3 hrs

3 hrs

Unit 4: ENZYMES 4.1. Definition, Chemical Nature and Importance of Enzymes 4.2. Nomenclature of Enzymes 4.3. Classification of Enzymes 4.3.1.IUPAC Classification

1. Interactive discussion 2. VCD Viewing 3. Virtual Reality Viewing 4. Picture and visual aid presentation 5. Puzzle activity 6. Case study Simulation

3 hrs

The students should have acquired knowledge regarding the nature of enzymes & enzyme kinetics, which gives them a deeper understanding of factors which may influence the performance of tests.

Serviceoriented Emotional maturity Accountabil ity

Each student must obtain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written
Page 8 of 16

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

enzymatic reaction;

4.3.2.Enzyme Variants 4.3.3.Enzyme Classification in the Blood 4.4. Factors Affecting Enzyme Action 4.5. Enzyme Inhibition

Assignments 3. Research Works 4. Practical Examinations 5. Unit/Topic Quizzes 6. Performance rating (based on accuracy, contribution to research & wearing of lab gown & ID) 7. Major Examinations Lecture Interactive Discussion/ Dialogue Power point presentation Individual reading assignments with written report 5 hrs The students will actually perform the following activities and analyze the results obtained: Expt. No. 20: Saliva Expt. No. 21: Salivary Digestion Expt. No. 22: Bile and its Emulsifying Action Expt. No. 23: pH and Buffer solutions Expt. No. 24: Physical & Chemical Examination of Urine The students should have acquired basic management, supervision, administrative skills to contribute to the resolution of conflicts pertaining to laboratory management, implementation of changes in response to technology and laboratory procedures, development of safety management procedures and improvement of standards of practice. In addition, the student must have acquired basic understanding of the process of digestion Serviceoriented Emotional maturity Client sensitivity Accountabil ity Credibility Each student must obtain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written Assignments 3. Research Works 4. Practical Examinations 5. Unit/Topic Quizzes 6. Performance Rating (based on accuracy, contribution to research,
Page 9 of 16

At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Discuss the digestion of complex biomolecules in the body; 6. Obey protocols in the laboratory for the

Unit 5: BIOCHEMISTRY OF DIGESTION 5.1 Definition 5.2. Factors Affecting Digestion 5.3. Phases of Digestion 5.3.1 Salivary Digestion 5.3.2 Gastric Digestion 5.3.3. Intestinal Digestion 5.3.4. Pancreatic Juice 5.3.5. Intestinal Juice 5.3.6. Bile 5.4. Chemical changes in the large intestines and feces 5.4.1. Overview 5.4.2. Fermentation 5.4.3. Putrefaction 5.4.4. Deamination

3 hrs

3 hrs

3 hrs

3 hrs

3 hrs

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

maintenance of a clean & safe working environment; 7. Perform skillfully the procedures included in the laboratory experiments; 8. Apply the universal precautions; 9. Discuss the different laboratory hazards; 10. Demonstrate laboratory safety practices and proper waste disposal;

5.4.5. Decarboxylation 5.5. Detoxification Chemical Composition of Feces

and has developed an attitude of being responsible for his own professional development or continuing education

wearing of lab gown & ID) 7. Major Examinations

First Grading Coverage: FGE Subtotal At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Define terms associated with CHO; 6. Describe CHO according to composition, classification and chemical properties; 7. Discuss the metabolism of Unit 6: CARBOHYDRATES 6.1. Definition and General structure of CHO 6.2. Importance and Functions of Carbohydrates 6.3. Classification of Carbohydrates 6.3.1. Monosaccharides 6.3.2. Disaccharides 6.3.3. Polysaccharides 6.4. General Properties of Carbohydrates 6.5. Digestion and Absorption of Carbohydrates 6.6. Carbohydrate Metabolism 6.6.1. Glycolysis 6.6.2. Krebs cycle & Electron Transport Chain 6.6.3. Gluconeogenesis Lecture Interactive Discussion/ Dialogue Power point presentation Individual reading assignments with written report

16 hours 2 hours 18 hours 15 hrs The students will actually perform the following activities and analyze the results obtained: Expt. No. 8: Qualitative Tests for Carbohydrates Expt. No. 9: Qualitative Tests for Specific Sugars Expt. No. 10: Reducing Property of Sugars Expt. No. 11: Inversion of Sucrose Expt. No. 12: Starch Expt. No. 13: The students must have acquired basic management, supervision, administrative skills to contribute to the resolution of conflicts pertaining to laboratory management, implementation of changes in response to technology and laboratory procedures, development of safety management procedures and improvement of standards of practice. In addition, the students must have acquired an understanding of concepts relating to carbohydrates and

18 hours Serviceoriented Emotional maturity Accountabil ity Credibility Each student must obtain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written Assignments 3. Research Works 4. Practical Examinations 5. Unit/Topic Quizzes 6. Performance rating ( based on accuracy, contribution to research & wearing of lab
Page 10 of 16

3 hrs

3 hrs

3 hrs

3 hrs

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

CHO in the body; 8. Explain the mode of actions of different hormones in the maintenance of blood glucose levels; 9. Discuss the different processes involved in the maintenance of normal blood glucose; 10. Discern the importance of the knowledge of metabolism in keeping oneself healthy; 11. Appreciate the significance of the metabolism of different biomolecules in the maintenance of normal life processes; 12. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 13. Internalize the relationship that exists among the different metabolic pathways; 14. Develop a persevering attitude in studying intricate metabolic processes; 15. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 16. Perform accurately the tests that will identify carbohydrates;

6.6.4. Glucogenesis 6.6.4.1. Fructose Metabolism 6.6.4.2. Galactose Metabolism 6.6.5. Pentose Phosphate Pathway 6.6.6. Glycogen metabolism 6.6.6.1. Glycogenesis 6.6.6.2. Glycogenolysis 6.7. Clinical significance of Carbohydrate Metabolism 6.7.1. Diabetes mellitus 6.8. Glycogen storage diseases

Glycogen Expt. No. 14: Cellulose

has developed an attitude of being responsible for their own professional development or continuing education

gown & ID) 7. Major Examinations

Midterm Coverage: Midterm Exam: Subtotal:

16 hours 2 hours 18 hours

18 hours

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 11 of 16

At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Classify proteins according to structure and function; 6. Discuss the metabolism of amino nitrogen; 7. Illustrate the structures of the different amino acids; 8. Describe the metabolism of the different amino acids; 9. Discern the importance of the knowledge of metabolism in keeping oneself healthy; 10. Appreciate the significance of the metabolism of different biomolecules in the maintenance of normal life processes; 11. Obey protocols in the laboratory for the maintenance of a clean & safe working environment;

Unit 7: PROTEINS 7.1. Definition and Functions of Proteins 7.2. Classification of Proteins 7.3. Categories of Protein Structure 7.3.1. Primary Structure 7.3.2. Secondary Structure 7.3.3. Tertiary Structure 7.3.4. Quarternary Structure 7.4. Amino Acids 7.4.1. Definition and General Structure 7.4.2. Properties and Importance 7.4.3. Classification 7.4.3.1. According to the Variable group 7.4.3.2. According to Dietary Need 7.5. Digestion and Absorption of Dietary Proteins 7.6. Protein Metabolism 7.6.1. Nitrogen Equilibrium 7.6.2. Biosynthesis of Proteins 7.6.3. Biosynthesis of NPN Compounds and Urea 7.6.4. Degradation of Amino Acids -Decarboxylation -Transamination -Oxidative

Lecture Interactive Discussion/ Dialogue Power point presentation Individual reading assignments with written report

7 hrs

The students will actually perform the following activities and analyze the results obtained: Expt. No. 17: General Tests for Proteins Expt. No.18: Qualitative Tests for Amino Acids Expt. No.19: General Properties of Protein

The students must have acquired basic management, supervision, administrative skills to contribute to the resolution of conflicts pertaining to laboratory management, implementation of changes in response to technology and laboratory procedures, development of safety management procedures and improvement of standards of practice. In addition, the students must have acquired an understanding of concepts relating to proteins and has developed an attitude of being responsible for their own professional development or continuing education

Serviceoriented Emotional maturity Accountabil ity Credibility 3 hrs

Each student must obtain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written Assignments 3. Research Works 4. Practical Examinations 5. Unit/Topic Quizzes 6. Performance rating ( based on accuracy, contribution to research & wearing of lab gown & ID) 7. Major Examinations

3 hrs

3 hrs

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 12 of 16

12. Internalize the relationship that exists among the different metabolic pathways; 13. Develop a persevering attitude in studying intricate metabolic processes; 14. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 15. Perform accurately the tests that will characterize proteins At the end of the term, the student is expected to: 1. Define the different terms encountered in Biochemistry. 2. Explain the physiological importance of the different bio-molecules. 3. Explain the chemical reactions which underlie the results obtained in the biochemistry laboratory and relate its importance in the clinical aspect of the course. 4. Analyze certain basic biochemical processes to explain commonly occurring health-related problems. 5. Describe terms associated with lipids; 6. Describe lipids according to composition, classification, properties;

Deamination 7.6.5. Metabolism of the Carbon Skeletons of Amino acids 7.6.5.1. Ketogenic Amino Acids 7.6.5.2. Glucogenic Amino Acids 7.6.5.3. Clinical Significance of Protein Metabolism

Unit 8: LIPIDS 8.1. Definition and Functions of Lipids 8.2. Classification of Lipids 8.2.1. Derived Lipids 8.2.2. Simple Lipids 8.2.3. Complex / Compound Lipids 8.2.4. Miscellaneous Lipids 8.3. Properties of Lipids 8.4. Digestion and Absorption of Dietary Lipids 8.5. Lipid Metabolism 8.5.1. Lipolysis 8.5.2. Knoops Beta Oxidation of Fatty acids 8.5.3. Ketogenesis 8.5.4. Lipogenesis 8.5.5. Cholesterol metabolism

Lecture Interactive Discussion/ Dialogue Power point presentation Individual reading assignments with written report

10 hrs

The students will actually perform the following activities and analyze the results obtained: Expt. No.15: Triglycerides Expt. No.16: Lipids from Brain

The students must have acquired basic management, supervision, administrative skills to contribute to the resolution of conflicts pertaining to laboratory management, implementation of changes in response to technology and laboratory procedures, development of safety management procedures and improvement of standards of practice. In addition, the students must have acquired an understanding of concepts relating to lipids and has

3 hrs

Serviceoriented Emotional maturity Accountabil ity Credibility

Each student must obtain at least 70% of the total scores in the following assessments: 1. Individual and/or Group Exercises 2. Reading and Written Assignments 3.ResearchWork 4. Practical Examinations 5. Unit/Topic Quizzes 6. Performance rating ( based on accuracy, contribution to research & wearing of lab gown & ID)
Page 13 of 16

3 hrs

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

7. Discuss the metabolism of lipids in the body; 8. Discern the importance of the knowledge of metabolism in keeping oneself healthy; 9. Appreciate the significance of the metabolism of different biomolecules in the maintenance of normal life processes; 10. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 11. Internalize the relationship that exists among the different metabolic pathways; 12. Develop a persevering attitude in studying intricate metabolic processes; 13. Obey protocols in the laboratory for the maintenance of a clean & safe working environment; 14. Perform accurately the tests that will manifest the properties of lipids;

8.6. Clinical Significance of Lipid Metabolism 8.6.1. Obesity 8.6.2 Lipid Storage Diseases

developed an attitude of being responsible for their own professional development or continuing education

7. Major Examinations

Finals Coverage: Finals Exam: Subtotal:

16 hours 2 hours 18 hours

18 hours

II.

GRADING SYSTEM: : Memorandum CCMT No. 3 series of 2007: Guidelines for the computation of grades for BSMT/BMLS professional subjects: Computation of grades for the grading period for combined lecture and laboratory subjects shall be 50%:50%; Laboratory grade shall be computed 30% experiments plus 70% class standing. Thus, three transmutation tables will be prepared.

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 14 of 16

Article IX. Section 8 of 2010 ed. UB student handbook: University policy on the grading system -Grade equivalent determination: There are three (3) grading periods (first grading, midterms & finals) for each semester. The cumulative system of computing grades shall be followed. Grades computed for midterms and finals are considered tentative. The final midterm grade is calculated by getting 1/3 of the first grading grade plus 2/3 of the tentative midterm grade and the final grade is computed by getting 1/3 of the midterm grade plus 2/3 of the tentative final grade; All failing grades in the final grading period are converted to 70; Highest Possible Score (HPS) refers to the sum total points of all quizzes, unit tests, assignments and/ or projects, and periodical examinations given or administered within the grading period. Students Actual Total Score (SATS) refers to the total score obtained by the student in the given quizzes, unit tests, assignments and/ or projects, and periodical examinations. Lowest Possible Score (LPS) refers to the cut off score as indicated. Cut-off Score. The cut-off point which determines the lowest passing score. General Education Subjects in Non-Board and Board Programs 70% equivalent to 75.

III.

REFERENCES th Textbook: Caret, Robert L.; Denniston, Katherine J. & Topping, Joseph J. (2004). Principles and Applications of Inorganic, Organic and Biochemistry (6 ed) Iowa, USA: Times Mirror Higher Education Group, Inc..

References: A. Books 1. Hein, Morris, Best, Leo, Pattison, Scott & Arena, Susan (2004). Introduction to General, Organic and Biochemistry (8 ed.). California: Brooks/Cole Publishing Co. 2. Bernaldez, Alicia T. & Hessari, Cecilia B. (2001) Basic Biochemistry for Health and Food Science Courses: Outlines and Notes. Manila, Philippines: UST Publishing House. 3. Angeles, Chita Celeste C. and Panlasigui, Leonora N. (2004) Fundamentals in Nutrition and Biochemistry, Manila, Philippines: NDAP. rd 4. McKee, T. & Mckee, J. (2003) Biochemistry: The Molecular Basis, (3 ed.) Philadelphia, USA: McGraw-Hill Book Co.
th

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 15 of 16

SCHOOL OF NATURALSCIENCES General Luna Road, Baguio

Prepared by: BSMLS/BSMT Professional Subjects Instructors

Noted by:

JUVYLINE P DIZON, RL Head- AMS Section-Library

ERLINDA P SANCHEZ, RMT, LlB, MPA Program Chair BMLS

Approved by:

Dr. JANICE KAYLYN K LONOGAN, RMT, RT, AMT Dean, School of Natural Sciences

Course Number: BIOCHM2 (5 units: 3u lec and 2u lab)

Course Description: Biochemistry

Effectivity: 1st Semester, SY 2013-2014

Date Revised: May 29, 2013

Page 16 of 16