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Course title and number Term Meeting times and location ECEN 660: BioMEMS and Lab-on-a-Chip Spring 2014 Tu/Th 12:45PM 2:00PM, ZEC 223A Lecture: 3 hours Credit: 3 Lab: 0 hours

Course Description and Prerequisites Introduction to BioMEMS and Lab-on-a-Chip; microfabrication techniques for BioMEMS device fabrication; Microfluidic devices and systems; microsystems for chemical and biomedical applications. Course Prerequisites: None. Learning Outcomes or Course Objectives The objective of this course is to introduce students into the BioMEMS and Lab-on-a-Chip field, which is the application of micro and nano technologies for biological and medical applications. Students learn basics in micro/nano fabrication, with a strong emphasis on fabrication methods for polymer based BioMEMS devices such as soft lithography, injection molding, micro contact printing to name a few. Microfluidic components such as microvalve, micropump, and microfluidic channels that form the key functional blocks in Lab-on-a-Chip devices are introduced. With this knowledge, students than learn BioMEMS applications in separation, minimally invasive diagnosis tools, implantable devices, drug delivery, optofluidics, and microsystems for cellular studies and tissue engineering. NO prior knowledge or experience in biology required. Instructor Information Name Telephone Email address Office hours Office location Prof. Arum Han, Department of Electrical and Computer Engineering 979-845-9686 arum.han@ece.tamu.edu Appointment by Email 309C WEB Textbook and/or Resource Material Textbooks: S. S. Saliterman, Fundamentals of BioMEMS and Medical Microdevices, Wiley, 2005 Class notes and handouts

References: A. Manz, H. Becker, Microsystem Technology in Chemistry and Life Sciences, Springer, 1999 O. Geschke, H. Klank, and P. Telleman, Microsystem Engineering of Lab-on-achip Devices, John Wiley & Sons, 2nd Edition, 2004 M. J. Madou, Fundamentals of Microfabrication, CRC Press, 2nd Edition, 2002

G. T. A. Kovacs, Micromachined Transducers Source Book, MacGraw-Hill, 1998 N. T. Nguyen, S. Wereley, Fundamentals and Applications of Microfluidics, Artech House Publishers, 2002 Grading Policies Homework & attendance: 10% Midterm: 30% Final: 30% Term Project (paper and presentation): 30% Project paper and presentation will be graded based on how good of a review you provide for your selected topic, how logical, innovative, and feasible your proposed idea is, and how well you present your work to the class. Your grades will be calculated on the basis of total points earned. The points can be curved based on class average and may lower the following standard. Grading Scale (out of 100): A: 90-100; B: 80-89; C: 70-79; D: 60-69; F: 59 or lower Course Topics, Calendar of Activities, Major Assignment Dates Week 1 2 3 4 5 6 7 8 9 10 Topic (tentative, subject to change) Introduction to MEMS and BioMEMS Microfabrication techniques for MEMS Microfabrication techniques for BioMEMS I Microfabrication techniques for BioMEMS II MEMS Actuators Principles of Microfluidics Surface Chemistry Microfluidic devices I Microfluidic devices II Microfluidic devices III Miniaturized Chromatography systems Midterm (2/20) Chemical analysis systems Particle separation systems Drug delivery devices Implantable devices Microsystem for DNA/Protein analysis Minimally invasive diagnosis tools Neural Interface Microsystems for Cellular studies I

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Microsystems for Cellular studies II Microsystem for Tissue Engineering BioMEMS Packaging Nanotechnology in BioMEMS I Nanotechnology in BioMEMS II TBD TBD Class Presentations I Class Presentations II Final Exam: 4/24 (during regular class hour)

Late Submission Late submissions of assignments will be accepted only in the case of University excused absences. Academic Integrity For additional information please visit: http://www.tamu.edu/aggiehonor An Aggie does not lie, cheat, or steal, or tolerate those who do. The handouts used in this course are copyrighted. The definition of "handouts" is all materials generated for this class, which include but are not limited to syllabi, homework assignments, inclass materials, and additional printed materials except published scientific papers for personal use. Because these materials are copyrighted, you do not have the right to make additional copies of the handouts unless the instructor of this course expressly grants permission. As commonly defined, plagiarism consists of passing off the ideas, words, writings, etc., of another as ones own. In accordance with this definition, you are committing plagiarism if you copy the work of another person without proper citation and acknowledgement, and turn it in as your own, even if you should have the permission of that person. Plagiarism is one of the worst academic offenses, for the plagiarist destroys the trust among colleagues without which research cannot be safely communicated. Paraphrasing without proper citation and acknowledgement is one form of plagiarism. If you have any questions regarding plagiarism, please consult the latest issue of the Texas A&M University Student Rules, under the section "Scholastic Dishonesty". Any forms of dishonesty including, but not limited to, cheating on any examinations and plagiarism on the Review project will be handled according to the procedures outlined by the Aggie Honor System Office. Please check the following websites for further information: University Regulations Student Handbook: http://student-rules.tamu.edu Definition of Academic Misconducts: http://www.tamu.edu/aggiehonor/acadmisconduct.htm Americans with Disabilities Act (ADA) The Americans with Disabilities Act (ADA) is a federal anti-discrimination statute that provides comprehensive civil rights protection for persons with disabilities. Among other things, this legislation requires that all students with disabilities be guaranteed a learning environment that provides for reasonable accommodation of their disabilities. If you believe you have a disability requiring an accommodation, please contact Disability Services, in Cain Hall, Room B118, or call 845-1637. For additional information visit http://disability.tamu.edu