COURSE SYLLABUS

Course Code Course Credit Pre-Requisites Course Description : PATHOLOGY : 2 units lecture (no laboratory) : Gross and Organ System Anatomy, Physiology :

Fundamentals of general pathology with emphasis on cellular adaptive and tissue/cellular reaction to inflammation and injury, degenerative processes and tissue repair. Course Objectives :

At the end of the course, the students are expected to; 1. Discuss cellular adaptations. 2. Discuss tissue and cellular reaction to inflammation and injury, degenerative process and tissue repair. Course Content
Week

:
Topic Learning Objective (General) Task (What student should do to prepare for the class) Reading /Research Reference

A.Cellular Adaptations Types of Cellular Adaptation 1. Atrophy 2. Hyperthrophy 3. Hyperplasia 4. Metaplasia 5. Dysplasia 6. Anaplasia Apoptosis

On completion of this chapter, the learner will be Homework, Home reading, able to: Seat work 1. Understand common terminologies use in pathology. 2. Discuss different types of cellular adaptation. 3.Correlate clinically the different types of cellular adaptation.

Robins Basic Pathology, Sniders.

B.Cellular Injury 1.Hypoxic Cell Injury 2.Free Radical Injury 3.Chemical Injury 4.Physical Injury B.Cellular Injury 5.Infectious Agents 6.Immunologic Reactions 7.Nutritional 8.Genetic Defects C.Types of Cellular Injury 1.Reversible Cellular Injury 2. Irreversible Cellular Injury D. Patterns of Acute Cell Injury 1. Necrosis E. Specific Morphologic Patterns of Necrosis 1.Coagulative Necrosis 2. Liquefactive Necrosis 3.Caseous Necrosis E. Specific Morphologic Patterns of Necrosis 4.Fat Necrosis a.Enzymatic Fat necrosis b.Traumatic Fat Necrosis 5.Gangrenous Necrosis a.Dry Gangrene b.Wet gangrene 4.Fibrinoid Necrosis F.Inflammation 1.Causes of inflammation 2.Patterns of Inflammation 3.Cardinal Sign of Inflammation 4.Players in Acute Inflammation 5. Inflammatory Cells

On completion of this chapter, the learner will be able to: 1. Describe the different Type of Cellular Injury. 2. Discuss the causes of each types. On completion of this chapter, the learner will be able to: 1. Describe the different Type of Cellular Injury. 2. Discuss the causes of each types. On completion of this chapter, the learner will be able to: 1. Describe the different Type of Cellular Injury. 2. Discuss the causes of each types. On completion of this chapter, the learner will be able to: 1.Differentiate different types of Necrosis. 2.Determine the physiologic and pathologic causes of the different type of necrosis. 3.Apply learning in clinical practice. On completion of this chapter, the learner will be able to: 1.Differentiate different types of Necrosis. 2.Determine the physiologic and pathologic causes of the different type of necrosis. 3.Apply learning in clinical practice.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders. Robins Basic Pathology, Sniders.

Homework, Home reading, Seat work

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

On completion of this chapter, the learner will be able to: 1.Identify the causes of inflammation. 2.Discuss the cardinal sign of inflammation.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

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F. Inflammation 6.Outcomes of Acute Inflammation 7.Chronic Inflamation G.Body Defenses Against Injury 1.Physical Barrier 2.Chemical Barrier 3.Tissues/Organs 4. Mononuclear Phagocytic System H.Immune System 1. Terminology 2.Types of Immunity a.Natural or Innate b. Acquired Immunity adaptive

On completion of this chapter, the learner will be able to: 1. Discuss the outcome of inflammation On completion of this chapter, the learner will be able to: 1.Discuss the different bodys protection..

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders. Robins Basic Pathology, Sniders.

Homework, Home reading, Seat work

On completion of this chapter, the learner will be able to: 1.Discuss the different types of immunity.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

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H.Immune System 1. Types of Acquired Immunity 2. Cells of the Immune System 3. Types of Immunoglobulin 4. Types of Hypersensitivity Reaction

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I.Degenerative Process 1. Degenerative Joint Diseases (Osteoarthritis) 2.Clinical Pattern of DJD. 3.Morphology 4.Pathogenesis 5. Clininical Features I.Degenerative Process 1.Rheumatoid Arthritis 2.Morphology

On completion of this chapter, the learner will be able to: 1.Identify and discuss the types of acquired immunity. 2. Discuss the function of different cells of immune system 3.Differentiate different types of immunoglobulin and hypersensitivity reaction. On completion of this chapter, the learner will be able to: 1.Identify and discuss the etiology of the disease 2.Discuss the Pathogenesis and morphology of the disease. 3.Explain the clinical features of the disease.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

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On completion of this chapter, the learner will be able to: 1.Identify and discuss the etiology of the disease 3

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

3.Pathogenesis 4.Clinical Features

2.Discuss the Pathogenesis and morphology of the disease. 3.Explain the clinical features of the disease.

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I.Degenerative Process 1. Gout and Gouty Arthritis 2.Pathogenesis 3.Morphology 4. Clinical Correlation

On completion of this chapter, the learner will be able to: 1.Identify and discuss the etiology of the disease 2.Discuss the Pathogenesis and morphology of the disease. 3.Explain the clinical features of the disease.

Homework, Home reading, Seat work

Robins Pathology, Sniders.

Basic

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I.Degenerative Process 1. Amyotrophic Lateral Sclerosis 2.Infantile Progressive Spinal Muscular Atrophy 3 Other Degenerative Disease

On completion of this chapter, the learner will be able to: 1.Identify and discuss the etiology of the disease 2.Discuss the Pathogenesis and morphology of the disease. 3.Explain the clinical features of the disease.

Homework, Home reading, Seat work

Robins Pathology, Sniders.

Basic

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J.Tissue Repair: 1. agents that causes injury leading to repair

On completion of this chapter, the learner will be able to: 1. Explain tissue repair. 4. Identify causes of injury leading to repair.

Homework, Home reading, Seat work

Robins Pathology, Sniders.

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J.Tissue Repair 2. consequences of injury - resolution of injury -tissue repair -fibrosis -conversion into chronic lesion

On completion of this chapter, the learner will be able to: 1.Identify and discuss the consequences of injury.

Homework, Home reading, Seat work

Robins Pathology, Sniders.

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J.Tissue Repair 1.Fibrosis 2.Scarring 3.Pathologic Processes 4.Pathogenesis :

On completion of this chapter, the learner will be able to: 1.Explain fibrosis and scarring

Homework, Home reading, Seat work

Robins Basic Pathology, Sniders.

Grading System

A. For Midterm Grade (1st half) Midterm 30% Preliminary test 20% Class Standing 50% Class Standing Components: Quizzes 15% Recitation 10% Projects 10% Assignment 10% Attendance 5% B. For Pre-Final Grade (2nd half) Final test 30% Pre-Final test 20% Class Standing 50% C. For Final Grade: Cumulative Midterm Grade 30% Pre-final Grade 70%

Official Textbook

: Vinay, K., CCotran, R.S. & Robbins, S. L., Robins Basic Pathology, Sniders.