Brand Name: Apo- Metoprolol, Betaloc, Lopressor, Novometropol

Generic Name: Metoprolol

Indications:
PO: used alone or in combination with other agents in the treatment of Hypertension
and Angina Pectoris
PO, IV: Prevention of Myocardial Infarction.
Unlabeled Uses: Prophylaxis and Treatment of Arrhythmias
Treatment of Hypertonic Cardiomyopathy
Mitral Valve Prolapse
Tremors
Symptomatic Treatment of Pheochromocytoma
Prevention of Vascular Headache
Management of Aggressive Behavior
Drug Classification: Antihypertensive – Beta-adrenergic blocker, Antianginal, Beta-
adrenergic blocker - selective
Mechanism of Action: Blocks stimulation of Beta1 adrenergic receptors with less effect
on Beta2 receptor sites
Dosage: Chronic treatment of hypertension, Angina; Myocardial Infarction Prophylaxis:
PO (Adults): 100-450 mg/day – single dose or bid.
Myocardial Infarction Prophylaxis – Acute Treatment
IV (Adults): 5mg q 2 min for 3 doses.
Special Precaution:
Pregnancy; Hyperthyroidism; Diabetes Mellitus; Lactation or Children
Pregnancy Risk Category: B
Adverse Reactions: CNS: Fatigue, Weakness, Dizziness, Depression, Memory Loss,
Mental Changes, Nightmares
EENT: Blurred Vision
Resp: Bronchospasm, Wheezing
CV: Bradycardia, Congestive Heart Failure, Pulmonary Edema, Peripheral
Vasoconstriction
GI: Constipation, Diarrhea, Nausea
GU: Impotence, Diminished Libido
Endo: Hyperglycemia, Hypoglycemia
Contraindications: Uncompensated Congestive Heart Failure; Pulmonary Edema;
Cardiogenic Shock; Bradycardia or Heart Block
(continuation Apo- Metoprolol, Betaloc, Lopressor, Novometropol)
Form: Tab 10mg x 100’s; 50mg x 100’s; 500’s
Nursing Responsibilities:
 General Info: monitor intake and output ratios and daily weight. Assess patient
routinely for evidence of fluid overload
 Hypertension: Monitor blood pressure and pulse frequently during period of
adjustment and periodically throughout therapy. Confer with physician prior to
giving drug if pulse is <50 bpm. Vital signs and ECG should be monitored every
5-15mins during and for several hrs after parental administration.
 Angina: Assess frequency and duration of episodes of chest pain throughout
therapy.
 Lab Test Considerations: May occasionally cause elevations in Potassium, Uric
Acid, Lipoprotein Levels, and BUN.
 Hepatic and renal function and CBC should be monitored periodically in
patients receiving prolonged therapy.