MEDICATION Anticoagulants

1.Dalteparin(Fragmin)

SIDE EFFECT

CARDIAC DRUGS
1. Inflammation of Skin caused by an Allergy Rash,itching/swelling (especially of the face/tongue/throat) severe dizziness, trouble breathing. 2.Inj site pain and tenderness; ecchymoses; haematoma.

2.Enoxaparin (Lovenox)

1.Mild irritation, pain, bruising, redness, or swelling at the injection site may oc 2.Fever,Diarrhea

Antiplatelet Agents
1.Aspirin 1.Conditions of Excess Stomach Acid Secretion 2.Irritation of the Stomach or Intestine 3.Heartburn 4.Ringing in the Ears 1.Conditions of Excess Stomach Acid Secretion 2.Dizzy 3.Itching

2.Ticlopidine

3.Clopidogrel

1.Hemorrhage 2.Bleeding of the Stomach or Intestines 3.Nosebleed 4.Eczema,Itching,Rash

4.Dipyridamole

1.Inflammation of Skin caused by an Allergy 2.Itching, Rash 3.Temporary Redness of Face and Neck 4. Head Pain 5.cardiac arrhythmias when given IV.

Angiotensin-Converting Enzyme (ACE) Inhibitors

1.Captopril 1.Tachycardia, palpitations 2.chest pain 3.pruritus 4.Hyperkalaemia.(muscle weakness, slow/irregular heartbeat)

2.Enalapril

3.Fosinopril 4.Perindopril 5.Ramipril

1.Dizziness, headache, fatigue 2.Persistent dry cough 3.Abnormal taste 4.Rash, neutropenia

1.Dizziness, lightheadedness, or tiredness 2.Dry cough 3.Severe stomach/abdominal pain, persistent nausea/vomiting.

Calcium Channel Blockers

1.Amlodipine 1.Dizziness, lightheadedness 2.swelling ankles/feet, or flushing 3.Hypotension, bradycardia

2.Nifedipine 3.Nimodipine

4.Verapamil

1.Dizziness and tiredness 2.Slow heartbeat 3.Constipation 4.Nausea, headache

5.Diltiazem

1.Headache, dizziness, fatigue 2.Ankle oedema, hypotension, 3.Flushing, nausea 4.GI discomfort, gingival hyperplasia, rashes

Beta-Blockers
1.Acebutolol

1.Dizziness or lightheadedness. (This side effect may be strongest when you get out of bed or rise from a chair. 2.Tiredness, cold hands and feet, headache, difficulty sleeping

2.Atenolol 3.Betaxolol 3.Sudden weight gain. Weight gain is common with an increase in your dose. 4.Increased shortness of breath, wheezing, difficulty breathing, skin rash, 5.slow, fast, or irregular heartbeat, 4.Bisoprolol 5.Metoprolol 6.Propranolol 6.swelling of feet and lower legs, or chest pain. 7.Vomiting or diarrhea. 8.Heartburn, constipation, or gas.

7.Sotalol 8.Timolol

Vasodilators
1.Nesiritide 2.Hydralazine 3.Nitrates and Minoxidil 1.Dizziness 2.Headache; rapid, irregular, or pounding heartbeat 3.Flushing of the face or neck. 4.Low blood pressure.

4.Isosorbide dinitrate

Digitalis
1.DIGOXIN 2.Digitoxin 1.Nausea, vomiting, headache 2.loss of appetite, and diarrhea 3.weakness, mental/mood changes 4.vision changes (such as blurred or yellow/green vision)

Statins
1.Simvastatin 2.Atorvastatin

1.Muscle pain/tenderness/weakness (especially with fever or unusual tiredness 2.Yellowing eyes/skin, dark urine 3.Severestomach/abdominal pain

4.Persistent nausea/vomiting. 3.Fluvastatin 4.lovastatin 5.Rosuvastatin

5.A very serious allergic reaction to this drug is rare. including: rash, itching/swelling (especially of the face/tongue/throat), dizzines

OTHER CARDIAC & ANTI ARRHYHTHMIC AGENTS

Amiodarone 1.Blue-grey discolouration of skin, photosensitivity, 2.Hot flushes, sweating. 3.Severe dizziness, fainting

ADENOSINE

1.Headache 2.Heart pounding, low blood pressure 3.nausea, sweating, flushinG 4.lightheadedness, sleep problems 5.coughing, and anxiety

QUINIDINE

1.Muscle weakness 2.nausea, vomiting, diarrhoea 3.cinchonism symptoms including impaired hearing, headache, blurred vision, dizziness and vomiting; urticaria and skin reactions. 1.Rash, myalgia 2.Hypersensitivity reactions (fever, agranulocytosis), 3.Severe hypotension 1.Dry mouth 2.Constipation 3.Urinary retention 4.Blurred vision,glaucoma 5.Rash 1.Nausea, vomiting, diarrhoea 2.constipation 3.oesophageal ulceration, confusion 4.lightheadedness, blurred vision 1.Dizziness, visual disturbances, lightheadedness 2.nausea, vomiting, headache, tremor, peripheral neuropathy

PROCAINAMIDE

DISOPYRAMIDE

MEXILETINE

FLECAINIDE

3.corneal deposits, blurred vision or seeing spots, IBUTILIDE 1.bradycardia, palpitations 2.headache; nausea, vomiting.

REMARKS/PRECAUTIONS

CARDIAC DRUGS
1. Inform to the Doctor

f the face/tongue/throat)

aematoma.

2. Monitor coagulation time. 3. Platelet count and stool occult blood test recommended during treatment 4. This medication can infrequently cause heavy bleeding. Be extra careful to avoid injuries (e.g., contact sports). Use an electric razor when shaving and a soft toothbrush when brushing your t

welling at the injection site may occur

1.Periodic blood counts, platelet count and stool occult blood test recommend 2. Inform to the Doctor

1.History of worsening breathing with runny/stuffy nose after taking aspirin 2.Limit alcoholic beverages, and stop smoking. 3.Do you see changes in behavior with nausea and vomiting?

1.Complete blood counts should be performed prior to therapy and every 2 wk during the first 3 mth of treatment. 2. Periodic LFT's to be done.

Limit alcoholic beverages. (Daily use of alcohol, especially when combined with this medicine, may increase your risk for stomach bleeding.)

1.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform suc 2.Limit alcoholic beverages. 3. Inform to Doctor

egular heartbeat)

1.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform suc 2.Limit alcoholicbeverages. 3.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position 4.Too much sweating, diarrhea, or vomiting may cause loss of too much body w (dehydration) and increase your risk of lightheadedness. drink enough fluids to prevent dehydration 1.PeriodicMonitoring of KFT's, S.Electrolytes, WBC count 2. Inform to doctor

Consider Severe hypotension and renal failure, angioedema. nausea/vomiting.

1.To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
2.May rarely develop worsening chest pain or a heart attack

after starting this medication or increasing the dose. 3.Inform to the Doctor symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of brea

1.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform suc 2.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position

1.Avoid abrupt withdrawal and long-term use. 2.Inform to the Doctor Bradycardia and those taking beta-blockers or digitalis are at risk of developing AV block, bradycardia, asystole or sinus arrest.

et out of bed or rise from a chair.) ifficulty sleeping

n with an increase in your dose. fficulty breathing, skin rash,

1.While you are taking a beta-blocker, you may need to record your pulse every If your pulse is slower than it should be, contact your doctor about taking your 2.Never stop taking a beta-blocker without speaking to your doctor first, even if you feel that it is not working. 3.Sudden withdrawal can worsen angina and cause heart attacks 4.Inform your doctor

1.While taking these drugs, have your blood pressure checked regul 2.S/e common on continuous use but resolves after the first few w If they persist, contact your doctor

1.Cardiac dysrhythmias, hypokalaemia, hypertension PeriodicMonitoring of KFT's, S.Electrolytes 2.Inform your doctor

lly with fever or unusual tiredness)

1.Limit alcoholic beverages. Daily use of alcohol may increase your risk for liver problems, especially when combined with rosuvastatin.

2.Inform your doctor

the face/tongue/throat), dizziness

1.This drug may cause your skin to be more sensitive to the sun. ----Avoid prolonged sun exposure to help prevent this effect. ----Use a sunscreen and wear protective clothing when outdoors. 2.Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. 3.PeriodicMonitoring of KFT's, S.Electrolytes

1.It can raise the level of uric acid in the blood stream and in the uri this might trigger a case of gout (red, hot, tender, swollen joints.)

2.can cause reduced blood flow to the heart and chest pain. It might worsen symptoms in patients with heart diseases such as c 1.Test dose is recommended. 2.PeriodicMonitoring of KFT's, S.Electrolytes

ing; urticaria and skin reactions. 1.Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. 2.PeriodicMonitoring of KFT's, S.Electrolytes

1.Correct potassium deficiency. 2.PeriodicMonitoring of KFT's, S.Electrolytes

1.Monitor ECG and BP. 2.Correct electrolyte imbalance prior to and during therapy. 3.Periodic Monitoring of LFT's, KFT's, S.Electrolytes

heral neuropathy

1.Monitor ECG, blood counts and plasma concentrations. 2.Correct electrolyte imbalances before initiating therapy.

3.hepatic impairment 1.Correct hypokalaemia and hypomagnesaemia 2.Monitor ECG during and for at least 4 hr after infusion.

ecommended during treatment vy bleeding. toothbrush when brushing your teeth

ool occult blood test recommended.

stuffy nose after taking aspirin (Rye's Syndrome)

a and vomiting?

d prior to therapy

ed with this medicine,

, use machinery, you are sure you can perform such activities safely.

, use machinery, you are sure you can perform such activities safely.

ying position may cause loss of too much body water eadedness.

WBC count

e, angioedema.

w/left arm pain, shortness of breath, unusual sweating.

, use machinery, you are sure you can perform such activities safely.

r digitalis are at risk of sinus arrest.

ay need to record your pulse every day. act your doctor about taking your beta-blocker that day. eaking to your doctor first,

cause heart attacks

our blood pressure checked regularly e but resolves after the first few weeks of treatment.

emia, hypertension

your risk for liver problems,

o be more sensitive to the sun. e to help prevent this effect. tective clothing when outdoors. nesium in the blood may also

in the blood stream and in the urine, and

o the heart and chest pain. ents with heart diseases such as chest pain and heart attack.

nesium in the blood may also

ior to and during therapy. T's, S.Electrolytes

plasma concentrations. before initiating therapy.

magnesaemia east 4 hr after infusion.