EIGHTH SEMESTER

Course Code Course Title Lectures (L) Hours per week 2 2 2 1 1 2 Tutorial (T) Hours per week 1 1 1 Practical (P) Hours per week Total Credits 3 3 3 1 1 2 Page No.

BPMPK 30604 BPMPK 40709 BPMPK 40802 BTMBS 40801 BTMBS 40802 BTMFR 40801 BTMGR 40801 BTMSH 40801 BTMJP 40801 BTMCE 40801 BPMTR 40850

Novel Drug Delivery System Pharmaceutical Clinical Research Pharmaceutical Industrial Management Communication Skill VI Behavioural Science VIII Foreign Language - VIII French German Spanish Japanese Chinese
Industrial/Research Institute/Corporate/Hospital Training

16 29

(3 Months) TOTAL

NOVEL DRUG DELIVERY SYSTEM

Course Code: 03 Course Objective:
Study of drug delivery and their application to therapeutics including drug administration.

BPMPK 30604

Credit Units:

Course Contents:
Module I Theory of Controlled release drug delivery systems. Release and diffusion of drugs from C.D.D.S., General methods of design and evaluation of C.D.D.S. Module II Carriers for drug delivery systems, Prodrugs, Physical, chemical and biomedical engineering approach to achieve controlled drug delivery. Microencapsulation: Methods, kinetics of drug release from microcapsules technology and applications. Module III Transdermal drug delivery systems: Theory, formulation and evaluation, Ionotophoresis. Implants and inserts: Types, design and evaluation methods, Osmotic pumps. Module IV Targeted Drug delivery systems: Concept of drug targeting, importance in therapeutics, methods in drug targeting, drug immobilization techniques, nanoparticles, liposomes, neosomes, pharmacosomes and erythrocytes. Module V Advances in drug delivery systems. An introduction to buccal, nasal, ocular pulmonary colonic delivery, etc. Examination Scheme:

Components Weightage (%)

A 5

CT 20

Ass/V/Q 5

EE 70

Note: A-Attendance, CT-Class Test, Ass/V/Q-Assignment/Viva/Quiz, EE-End Term Exam.

Text & References:

1 2 3 4 5 6 Robinson, Sustained and Controlled Drug Delivery Systems. Jolles and Wooldbridg, Drug Design: Facts of Fantasy. Robinson and Vincent, Controlled Drug Delivery Systems. Chien, Novel Drug Delivery Systems. Gutcho, Microencapsulation and Related Processes. Noxon, Microencapsulation.

PHARMACEUTICAL CLINICAL RESEARCH

Course Code: 03 Course Objective:
To study about clinical research, project management, data analysis etc.

BPMPK 40709

Credit Units:

Course Contents:
Module I : Clinical Research An introduction to clinical research, principles of pharmacology and drug discovery and development, roles and responsibilities of sponsor and investigators , Present Global scenario. Module II : Clinical trials and documentation Preparation and planning for Clinical trials, application for permission , approval for clinical trials, informed consent process, different Clinical trial designs, essential documentation in clinical trial , bioavailability/ bioequivalence studies, project management in clinical trials. Module III : Ethics in Clinical Research Ethical guidelines and regulatory aspects in conducting Clinical trials ( ICMR guidelines, WHO, ICH-GCP guidelines) Module IV: Clinical Data management Data capture methods, data entry, data review and validation, discrepancy management Module V: Drug safety and Pharmacovigilance An Introduction, basic principles, responsibilities of stake holders, national and international regulatory reporting norms. Examination Scheme: Components Weightage (%) A 5 CT 20 Ass/V/Q 5 EE 70

Note: A-Attendance, CT-Class Test, Ass/V/Q-Assignment/Viva/Quiz, EE-End Term Exam.

Text & References:

1 2 3 4 Hand book of ICH-Good Clinical Practice. ICMR guidelines for GCP. Drug and cosmetic Act-Schedule Y. Basic Principles of Clinical Research and Methodology by S.K. Gupta

PHARMACEUTICAL INDUSTRIAL MANAGEMENT

Course Code: 03 Course objective:
Familiarizing the modes of administrative management, economics accountancy, materials management etc.

BPMPK 40802

Credit Units:

Course Contents:
Module I: Concept of Management Administrative Management (Planning, Organising Staffing Directing and controlling). Entrepreneurship development, Operative Management (Personnel, Materials, Production, financial, Marketing, Time/space, Margin/Morale) Principles of Management (Co-ordination, Delegation of Authority/Responsibility. Record Keeping), Identification of key points to give maximum thrust for development and perfection. Module II: Economics Principles of economics with special reference to the Laws of demand and supply, demand schedule, demand curves labor welfare, general principles of insurance and inland and foreign trade, procedure of exporting and importing goods. Module III: Accounting Principles of Accountancy, Ledger posting and book entries preparation of trial balance, columns of a cash book, Bank reconciliation statement, rectification of errors, profits and loss account, balance sheet, purchase, keeping and pricing of stocks, treatment of cheques bills of exchange, promissory notes and bundies documentary bills. Module IV: Materials Management A brief exposure of basic principles of management major areas, scope, purchase, stores, inventory control and evaluation of materials management. ModuleV: Production Management A brief exposure of the different aspects of Production Management Visible and Invisible inputs, Methodology of Activities Performance Evaluation Technique Process Flow, Process Know-how, Maintenance Management. Module VI: Market Research (a) Measuring & forecasting Market Demand: Major concept in demand measurement, Estimating current demand Geo-demo-graphic analysis. Estimating Industry sales, Market share and future demand (b) Market Segmentation & Market Targeting. Examination Scheme: Components Weightage (%) A 5 CT 20 Ass/V/Q 5 EE 70

Note: A-Attendance, CT-Class Test, Ass/V/Q-Assignment/Viva/Quiz, EE-End Term Exam.

Text & References:

1 2 3 4 5 Chary S.N., Production and Operative Management/Tata Mc Graw Hill. Data A.K., Material Management/PHI. Shreenivasan K.R., An Introduction to Industrial Management-Vikas. Mukopadhyay Sekhar, Pharmaceutical Selling, Sterling Publishers. Vidya sagar Pharmaceutical Industrial Management, Pharma Book Syndicate.

Chadwick Leslie, The essence of management accounting /PHI.

COMMUNICATION SKILLS - VI
Course Code: Course Objective:
The modules are designed to enhance the communicative competence of the learners to equip them with efficient interpersonal communication.

BPMBS 40801

Credit Units: 01

Course Contents:
Module I: Dynamics of Group Discussion Introduction, Methodology Role Functions Mannerism Guidelines Module II: Communication through Electronic Channels Introduction Technology based Communication Tools Video Conferencing Web Conferencing Selection of the Effective Tool E-mails, Fax etc. Module III: Effective Public Speaking Types Essentials Success in Public Speaking Dos and Donts Examination Scheme: Components Weightage (%) C 5 CT 15 P 5 A 5 EE 70

Text & References:

1 2 3 4 Jermy Comfort, Speaking Effectively, et.al, Cambridge Krishnaswamy, N, Creative English for Communication, Macmillan Raman Prakash, Business Communication, Oxford. Taylor, Conversation in Practice

BEHAVIOURAL SCIENCE - VIII (PERSONAL AND PROFESSIONAL EXCELLENCE)

Course Code: Course Objective:
1 2 Importance of Personal and Professional excellence Inculcating the components of excellence

BPMBS 40802

Credit Units: 01

Course Contents:

Module I: Components of Excellence 1 Personal Excellence: o Identifying long-term choices and goals o Uncovering the talent, strength & style 2 Analyzing choke points in your personal processes by analysis in area of placements, events, seminars, conference, extracurricular activities, projects etc. Module II: Managing Personal Effectiveness 1 Setting goals to maintain focus 2 Dimensions of personal effectiveness (self disclosure, openness to feedback and perceptiveness) 3 Integration of personal and organizational vision for effectiveness 4 A healthy balance of work and play 5 Managing Stress creatively and productively Module III: Personal Success Strategy 1 Time management 2 Handling criticism and interruptions 3 Dealing with difficult people 4 Mapping and evaluating the situations 5 Identifying long-term goals Module IV: Positive Personal Growth 1 Understanding & Developing positive emotions 2 Positive approach towards future 3 Resilience during loss and challenge Module V: Professional Success 1 Building independence & interdependence 2 Reducing resistance to change 3 Continued reflection (Placements, events, seminars, conferences, projects extracurricular Activities etc.) Module VI: End-of-Semester Appraisal 1 Viva based on personal journal 2 Assessment of Behavioral change as a result of training 3 Exit Level Rating by Self and Observer

GERMAN - VIII
Course Code: 02 Course Objective:
To enable the students to converse, read and write in the language with the help of the basic rules of grammar, which will later help them to strengthen their language. To give the students an insight into the culture, geography, political situation and economic opportunities available in Germany Introduction to Advanced Grammar and Business Language and Professional Jargon

BPMGR 40801

Credit Units:

Course Contents:
Module I: Reading and comprehension Reading texts and comprehending them Module II: Information about German History

Acquiring information about German History through appropriate texts and stories Module III: Bio data/Curriculam vitae Writing a bio-data in the proper format with all essential components Module IV: Informal letters Reading and writing informal letters Module V: Business etiquette Business etiquette in Germany and types of companies Module VI: Interview skills To learn to face interviews Read a text Interviewspiel Module VII: Picture Description Firstly recognize the persons or things in the picture and identify the situation depicted in the picture; Secondly answer questions of general meaning in context to the picture and also talk about the personal experiences which come to your mind upon seeing the picture. Examination Scheme: Components Weightage (%) CT 15 H 5 V 5 A 5 EE1 70

Text & References:

43 44 45 46 47 48 Wolfgang Hieber, Lernziel Deutsch Hans-Heinrich Wangler, Sprachkurs Deutsch Schulz Griesbach, Deutsche Sprachlehre fr Auslnder P.L Aneja, Deutsch Interessant- 1, 2 & 3 Rosa-Maria Dallapiazza et al, Tangram Aktuell A1/1,2 Braun, Nieder, Schme, Deutsch als Fremdsprache 1A, Grundkurs

PHARMACEUTICAL MEDICINAL CHEMISTRY - II

Course Code: 03 Course objective:
To study of different drugs and their biological properties, also their quantitative structure activity relationships.

BPMPK 30606

Credit Units:

Course Contents:
Module I: Analgesics and Antipyretics Aspirin, Mefeanamic Acid, Ibuprofen, Sulphacetamide, Nalidixic acid. Diclofenac, Antibacterials: Sulphamethoxazole, Sulphadiazine,

Module II: Cadiovascular Agents Antianginal & vasodilators, antiarrhythmics, antihypertensives, anticoagulants, antihyperlipidemics & cardiotonics Nifedipine, Procainamide, Propranolol, Methyldopa, Captopril, Clofibrate, Warfarin, Phenidione.

Module III: Autocoids: Antihistaminics H1 antagonists: Diphenhydramine, Promethazine; Cyproheptadine, Cetrizine. H2 anagonists: Ranitidine, Famotidine. Antineoplastics: Chlorambucil, 5-Fluorouracil, Methotrexate. Module IV: Psychopharmacological Agents Neuroleptics: Imipramine, Amitryptyline, Antidepressants: Meprobamate, Chlordiazepoxide, Diazepam, Antispasmodic and Antiulcer drugs: Dicyclomine, Ranitidine, Omeprazole, Neuromuscular Blocking Agents: Gallamine Triethiodide, Mephenesin, Pancuronium. Examination Scheme: Components Weightage (%) A 5 CT 20 Ass/V/Q 5 EE 70

Note: A-Attendance, CT-Class Test, Ass/V/Q-Assignment/Viva/Quiz, EE-End Term Exam.

Text & References:

1 2 3 4 5 6 7 8 9 Mann P G & Saunders B C, Practical Organic Chemistry, ELBS/Longman, London. Wolff ME, Ed. Burger/s Medicinal Chemistry, John Wiley & Sons, New York. Fumiss B S, Hannaford A J, Smith P W G and Tathell A R, Vogels Textbook of Practical Organic Chemistry, The ELBS/Longman, London. Pharmacopoeia of India, Ministry of Health, Govt. of India. Foye W C, Principles of Medicinal Chemical, Lea 7 Febiger, Philadelphia. Nogrady, T, Medicinal Chemistry A Biochemical Approach, Oxford University Press, New York, Oxford. Finar I L, Organic Chemistry, Vol I & II, ELBS/Longman, London. Delagado J N and Remers W A R, Eds., Wilson and Gisworlds Text Book of Organic Medici nal and Pharmaceutical Chemistry, J. Lippincott Co., Philadelphia. Singh Harkishan and Kapoor, V.K., Organic Pharmaceutical Chemistry, Vallabh Prakashan, Delhi.