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White NisinA
Clear Pure Nisin A Solution

White NisinA Ultrapure NisinA Vegetable NisinA

In 2013, Handary created a clear, highly effective pure Nisin A solution, and provided a healthier, natural ingredient for food shelf life protection. This technology has entered the FiE Excellence Award Finalist. In 2012, Handary developed a five-step NaCl elution to remove Nisin A impurities. The obtained ultrapure nisin A shows high bactericidal activity against both Gram-positive and Gram-negative bacteria and is a tenfold improvement as compared to nisin traditionally obtained via the one-step elution. In 2010, Handary discovered a safer vegetable-sourced Nisin A, moving away from traditional dairy-based production, exclusively from renewable, non-GMO vegetal sources without allergens, which was honored the US IFT Expo Innovation Award.

White NisinA

The Key Benefits of White NisinA in Food Protection

Extend shelf life by controlling spoilage bacteria such as LAB and sporeformers Improve food safety by inhibiting pathogens such as S. aureus, Listeria, E. coli and Salmonella Maintain sensory properties with clear and taste-neutral solution Label friendly such as natural or as processing aid, antimicrobial solution

Minimum Inhibition Concentrations of White NisinA in Food Applications (W/W)


Beers & wines A. acidoterrestris Bacillus spp. Clostridium spp. E. Coli Lactic acid bacteria Listeria spp. Salmonella spp. S. Aureus Fruit juices 0.01% 0.025%

Dips, sauces & Dressings 0.025% 0.025% 0.05% 0.025% 0.05% 0.05% 0.05% Ready-to-eat meals 0.025% 0.025% Cheese

Yogurt, Cream 0.025% Milk, dairy drinks & desserts 0.025% 0.025% 0.025% 0.05%

Meat, Poultry and Beef

Enhanced meat, poultry and beef Cooked meat

0.025% 0.025% 0.05% 0.05% 0.05%

0.025% 0.2% 0.025% 0.05% 0.05% 0.05% 0.025% 0.05%



0.025% 0.05% 0.05%

White NisinA

White NisinA Topical Application vs. Standard Nisin

Your benefits A healthier ingredient Increased product shelf life Cost-efficiency Enhanced application to transparent drinks White NisinA Ultrapure Nisin A concentration Minimized interference of food components More than 4 times higher protection against gram-positive bacteria Enhanced activities against gram-negative bacteria Nisin efficiency is less influenced by fat and emulsifiers No- or negligible sedimentation Clear and taste-neutral solution Standard Nisin High non-nisin protein impurities and sodium chloride content Effective only against gram-positive bacteria Nisin efficiency is decreased by fat and emulsifiers A high grade of turbidity after dissolution in water and visible particles at the bottom of the bottle

Optimizing Protection of Drinks

Test in Fresh Apple Juices Figure 1. White NisinA

Protecting Drinks Naturally

White NisinA remained effective throughout shelf life as no LAB and spore-formers were detected after 18 days in fresh apple juice. In addition, the visual appeal of the drink was maintained as White NisinA provided a clear solution with negligible sedimentation.

White NisinA has a unique advantage in preventing off-flavors caused by spore-forming bacterium Alicyclobacillus acidoterrestris in fresh apple juices.

White NisinA - 100% Soluble for Optimal Clarity and Increased Dispersion

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Standard Nisin A and pure Nisin A in comparison to white NisinA

White NisinA

A new, pure, all natural, safe and effective antimicrobial for food and beverage market

Handary is an industrial leader in delivering combined rapid microbial diagnostics and natural protective solutions to effectively keeping food safer and fresher for longer.

More precisely, Handary is a pioneer and leader in supplying high-quality natural protective ingredients, including Antimicrobials Natap | Natalac Natamycin, Epolyly Polylysine, NisinA | NisinZ Nisin, Lysoch Lysozyme, Proteria Antimicrobial cultures, and Antimix Antimicrobial blends, Natural extracts Guardox Antioxidants, and Chitoly Mushroom chitosan, Fresh-keeping Enzymes Amylax Maltogenic amylase and GlucoX Glucose Oxidase, Shelf-life extenders Befresh Fresh-keeper and Shelfex Shelf-life extender.

Info@handary.com Tel: +32 23746314 Fax: +32 23747909 Avenue de Fr 267 1180 Brussels, Belgium

Freshcare for Quality


White NisinA