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The feto-placental unit


EMBRYOLOGY AND ANATOMY:
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EMBRYOLOGY AND ANATOMY:
Moore & Persaud: The developing human- Clinically oriented embryology
EMBRYOLOGY AND ANATOMY:
Moore & Persaud: The developing human- Clinicall y oriented embryology
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EMBRYOLOGY AND ANATOMY: FETAL SURFACE
EMBRYOLOGY AND ANATOMY:MATERNAL SURFACE
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HISTOLOGY: UMBILICAL CORD
Decidua
Chorion
Amnion
HISTOLOGY: MEMBRANES
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HISTOLOGY: PLACENTAL DISC
HISTOLOGY: PLACENTAL DISC-FETAL SURFACE
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HISTOLOGY: PLACENTAL DISC- MATERNAL SURFACE
Moore & Persaud: The developing human- Clinically oriented embryology
HISTOLOGY: VILLOUS ARCHITECTURE
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HISTOLOGY: VILLOUS ARCHITECTURE
Moore & Persaud: The developing human- Clinically oriented embryology
FUNCTIONS OF THE PLACENTA
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Placental Endocrine Functions : Steroid Hormones

MOTHER PLACENTA FETUS

LDL Cholesterol LDL Cholesterol LDL
Cholesterol
(Blood) (Blood)
Progesterone
DHEAS DHEAS DHEAS
(Adrenal) (Adrenal)
Sulfatase
3 BetaOH steroid DH
Aromatase
Estrone
Estradiol

Key:
DHEAS : Dehydroepiandrosteronesulfate
3 BetaOH steroid DH : 3 betahydroxy steroid dehydrogenase
Figuremodified from: Carr, BR, Thematernal-fetal-placental unit. In: Becker KL,
ed. Principles and Practiceof Endocrinology and Metabolism, 3
rd
ed. Lippincott
Williams & Wilkins, Philadelphia. 2001: 1061.
DEVELOPMENTAL PROBLEMS
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ECTOPIC IMPLANTATION
Moore & Persaud: The developing human- Clinically oriented embryology
PLACENTA PREVIA & PLACENTA ACCRETA
Moore & Persaud: The developing human- Clinically oriented embryology
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MECHANICAL PROBLEMS
MECHANICAL PROBLEMS
CORD KNOTS & TWISTS
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CORD: VELAMENTOUS INSERTION
Kaplan: Color atlas of gross placental pathology.
ABNORMAL MEMBRANE ATTACHMENT
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MEMBRANE RUPTURE: AMPUTATIONS
INFLAMMATION: CHORIOAMNIONITIS
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Acute Funisitis
Candida Funisitis
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Candida Funisitis
Normal membranes
Decidua
Chorion
Amnion
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Acute chorioamnionitis
Meconium
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Acute villitis
Acute intervillositis.
Placental infection: Listeria
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Listeriosis
Placental Microabscesses
Villous necrosis
Heavy growth of Listeria in postmortem cultures
TRANSPLACENTAL (TORCH) INFECTIONS
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Parvoviral inclusions in villi
Cytomegalovirus: Characteristic nuclear inclusions
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Chronic Villitis (non-specific)
VASCULAR PROBLEMS
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VASCULAR: THROMBOSIS IN FETAL VESSELS
VASCULAR: FETOMATERNAL HEMORRHAGE
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Vascular: Pre-eclampsia
Vascular: Pre-eclampsia - fibrinoid change, foamy histiocytes
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Vascular: Placental Infarct
Vascular: Placental Infarct
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Vascular: Placental Abruption
Vascular: Placental Abruption
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NEOPLASIA
CHORANGIOMA
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CHORANGIOMA
HYDATIDIFORM MOLES
COMPLETE = Diploid
2 Pat, 0 Mat.
PARTIAL = Triploid
2 Pat, 1 Mat
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MULTIPLE GESTATIONS
Twin placenta- fused discs
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Dichorionic Diamnionic placenta
Monochorionic Diamnionic placenta
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Monochorionic twins with Vascular anastomosis
Twin-Twin transfusion syndrome
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Twin placenta- Monoamnionic, with entangled cords
Twin placenta- fetus papyraceus
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The feto-placental unit