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BIOL 350 Exam 3 Fall 2010

BIOL 350: General Microbiology


Exam 3
VERSION A
Before beginning:
Write your name at the top of this cover sheet. Do not remove the staple.
Write your name and red ID on your scantron.
Write down which exam version (color of top sheet) you have
Check to make sure that your test has all 40 questions.
Read each question carefully.
This exam is worth 100 points. Each question is worth 2.5 points.
Good luck!

BIOL 350 Exam 3 Fall 2010
1. What is true of Cryptophyte Algae?
A. They all have choroplasts
B. They have two nuclei
C. They move using pseudopods
D. All of the above are correct
E. A and B are correct
2. Which of the following describes
the symbiotic relationship known as a
mutualism?
A. both species benefit in an
unspecific manner
B. one species preys upon another
C. one species benefits while the
other is harmed
D. one species benefits while the
other is unaffected
E. both species benefit and depend on
each other
3. What is TRUE about deep-sea thermal
vent ecosystems?
A. Most of the diversity is inside
tube worms
B. They have many halophiles
C. Detritus is their main carbon
source
D. All of the above
E. None of the above
4. Which of the following is the major
PRODUCER in terrestrial ecosystems?
A. Nitrogen-fixing bacteria
B. Plants
C. Fungi
D. Bacteria
E. Protists
5. What is TRUE of the human
genitourinary microflora?
A. Lactobacillus can prevent
establishment of pathogens
B. Propionbacteria are abundant in
this microflora
C. Healthy bladders are full of
bacteria
D. The microflora needs to tolerate
high pH
E. None of the above.
6. What is TRUE about the intestine
and its microflora?
A. The low pH of impedes bacterial
growth.
B. The vast majority of human-
associate bacteria live here.
C. Streptococcus are dominant here.
D. Helicobacter pylori commonly infect
intestine walls.
E. It selects for salt-tolerant
bacteria.
7. Bacteroides thetaiotaomicron is
important to human health because it:
A. Prevents Helicobacter establishment
B. Helps digest food in the stomach
C. Helps break down complex
carbohydrates
D. All of the above
E. None of the above
8. Which of the following is part of
the skin condition called acne:
A. A pathogenic microbe invades the
hair follicle
B. The causal agent feeds on hormones
release in puberty
C. The causal agent is found on normal
healthy skin
D. All of the above
E. None of the above
9. Skin is difficult to colonize
because:
A. The high pH
B. It tends to have low moisture
C. Staphylococcus epidermis keeps out
other bacteria
D. Skin is only able to be colonized
in puberty
E. All of the above
10. African sleeping sickness is
caused by a:
A. A Trypanosome
B. Giardia
C. Paramecium
D. An Ameobozoan
E. None of the above
BIOL 350 Exam 3 Fall 2010
TRUE or FALSE questions
11. Synergism is a specific
interaction where both partners
benefit.
A. True
B. False
12. The mouth has the highest
proportion of anaerobes of any human
microbial ecosystem
A. True
B. False
MATCHING QUESTIONS:
Questions 13-16: Match each of the
following items with the BEST match
below. Only one answer per question,
but a letter may be used more than
once or not at all.
(A) Barophilic
(B) Benthos
(C) Neuston
(D) Aerated horizon
B 13. Water contacts ocean floor
A 14. Loves high pressure
C 15. Air-water interface
D 16. Decomposed material
Questions 17-20: Match each of the
organisms with the BEST match below.
Only one answer per question, but a
letter may be used more than once or
not at all.
(A) Yeast
(B) Brown Algae
(C) Basidiomycetes
(D) Ciliates
B 17. Energy storage lipid
C 18. Fruiting body
D 19. RNA made in Macronucleus
C 20. Gametes fuse, but not nuclei
21. Helicobacter pylori is associated
specifically with what disease?
A. stomach ulcers.
B. colon cancer.
C. diarrhea.
D. food poisoning.
E. meningitis
22. Bacteria virulence factors that
are grouped together and typical have
a lower GC content can be found on
which of the following elements?
A. pathogenicity islands.
B. plasmids.
C. transposons.
D. bacteriophage.
E. all of the above
23. Which organism that is responsible
for dangerous outbreaks is resistant
to almost every antibiotic therapy?
A. Streptococcus pneumoniae.
B. Neisseria meningitidis
C. Helicobacter pylori.
D. Vibrio cholerae.
E. Klebsiella pneumoniae.
24. Which structure largely helps a
bacterium avoid phagocytosis?
A. capsule
B. flagella
C. peptidoglycan
D. S-layer
E. pili
25. Which of the following are
bacterial virulence factors that
can create a channel in host cell
membranes causing the host cell to
lyse?
A. pathogenicity islands
B. pili
C. invasins
D. toxins
E. all of the above
BIOL 350 Exam 3 Fall 2010
26. Staphylococcus aureus that is
resistant to multiple antibiotics
such as methicillin encdodes an
alternative Penicillin Binding
Protein encoded on which mobile
genetic element?
A. plasmid
B. transposon
C. bacteriophage
D. pathogenicity island
E. none of the above
27. An antibiotic which prevents
growth of the organism is
considered to be what?
A. bactericidal
B. broad spectrum
C. narrow spectrum
D. bacteriostatic
E. all of the above
28. Which process of the bacterial
cell serves as an ideal target for
antibiotic therapy?
A. cell wall synthesis
B. DNA replication
C. protein synthesis
D. Transcription
E. all of the above
29. Which of the following does NOT
characterize Innate immunity?
A. involves highly specialize
phagocytic cells
B. an important first line of
defense
C. recognizes PAMPs
D. characterized by long-lived
specific memory
E. utilizes antimicrobial peptides
30. Which of the following is
considered a PAMP that is
recognized by toll like receptors?
A. lysozyme
B. antimicrobial peptides
C. peptidoglycan
D. TTSS
E. all of the above
31. Which is the key component in
extracellular traps which
ensnares the bacteria?
A. antimicrobial peptides
B. lysozyme
C. DNA
D. pili
E. neutrophils
32.
The antibacterial activity of the
antibiotic shown above is conferred
by which important component
(depicted by arrow)?
A. Thiazolidine
B. Beta lactamase
C. Beta lactam ring
D. D-ala- D-ala peptide
E. N-acetylglucosamine
33. Tetracycline works by which
process?
A. Binds the ribosomal large subunit
to block transfer of peptides
B. Prevent 30s and 50s ribosomal
subunits from binding each other
C. Competitive inhibitor of
crosslink transpeptidation
D. Binds the small ribosomal subunit
to block binding of aminoacyl-
tRNA
E. B & D
BIOL 350 Exam 3 Fall 2010
34. Virulence factors in Bacillus
anthracis are encoded on which
mobile genetic element?
A. plasmid
B. transposon
C. bacteriophage
D. pathogenicity island
E. A & B only
35. Spontaneous mutations may result
in which form of antibiotic
resistance acquisition?
A. destroying the antibiotic
B. modification of the antibiotic
C. drug efflux pump
D. modification of antibiotic target
E. all of the above
36. Which form of Anthrax infection in
the most deadly?
A. Inhalational
B. Cutaneous
C. Oropharyngeal
D. Gastrointestinal
E. all of the above
37. Which bacterium that causes
meningitis does so primarily in
newborns?
A. Streptococcus pneumoniae
B. Hemophilus influenzae
C. Neisseria meningitidis
D. Group B streptococcus
E. Listeria monocytogenes
38. For which bacterium that causes
meningitis is there a highly
effective vaccine?
A. Streptococcus pneumoniae
B. Hemophilus influenzae
C. Neisseria meningitidis
D. Group B streptococcus
E. Listeria monocytogenes
39. Which mineral is being used to
help cure diarrhea?
A. Chloride
B. Vitamin B
C. Iron
D. Mercury
E. Zinc
40. What is the correct order of the
events in phagocytosis?
1) Discharge of waste material; 2)
Fusion of the phagosome with a
lysosome; 3) Adherence of the
microbe to phagocytes; 4) Digestion
of ingested microbe; 5) Formation
of a phagosome; 6) Ingestion of
microbe by phagocyte.
A. 3, 6, 5, 2, 4, 1
B. 3, 4, 6, 5, 2, 1
C. 6, 5, 2, 4, 3, 1
D. 5, 2, 3. 6, 4, 1
E. 6, 3, 5, 4, 2, 1