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You are advised also to read About this journal, which includes other relevant information.

All submitted manuscripts should contain original research not previously published and not
under consideration for publication elsewhere. All authors have read and agreed to the
manuscript content, and that any experimental research that is reported in the manuscript has
been performed with the approval of an appropriate ethics committee. Manuscripts may be
rejected if the editorial office considers that the research has not been carried out within an
ethical framework. Papers must be written in English and manuscripts may be submitted for
consideration as full articles, short reports or reviews. Authors are urged to keep the length of
regular papers to six printed pages or fewer. Short Reports can be no longer than four printed
pages, including all spaces, references, figures and tables. Manuscripts must be submitted by
one of the authors of the manuscript, and should not be submitted by anyone on their behalf.
The submitting author takes responsibility for the article during submission and peer review.
Article-processing charges
JTLS levies an article-processing charge for every accepted article, to cover the costs
incurred by publication. Hence, In 2011 the article-processing is still free of charge.

Preparing manuscript text

File formats

Format the manuscript similar to a published paper and file formats should be in Microsoft
Word or Rich text format (RTF). Users of other word processing packages should save or
convert their files to RTF before uploading. The text should be single-spaced with 2.5 cm
margins on the left and right sides in A4 size. the "Abstract" through "Discussion" sections
should be in double column format. Title and running title sections, as well as references,
footnotes, figure legends and tables, should remain in single-column format. Use 11-point
Times New Roman font, and select size and bolding to mimic the appearance shown above
for the title section. Do not imbed graphics in the Word document, but add them at the end of
the Manuscript. Prepare figures at publication-quality resolution, using only applications
capable of generating high-resolution TIFF or JPG files.

Manuscripts for Research articles submitted to JTLS should be divided into the following
sections:

Title page
The title should be short and to the point, which should include an accurate, clear and concise
description of the reported work, avoiding abbreviations. The surname and initials of each
author should be followed by his or her department, institution, city with postal code and
country. The corresponding author should also be indicated. Please provide a running title of
not more than 60 characters and from 3 to 7 keywords.


Abstract
The abstract of the manuscript should not exceed 350 words, abide strictly by this limitation
of length. The abstract should comprehensively but succinctly describe the contents of the
paper to the reader, and abbreviations and reference citations should be avoided.

Background
The background section should be written from the standpoint of researchers without
specialist knowledge in that area and must clearly state - and, if helpful, illustrate - the
background to the research and its aims. The section should end with a very brief statement
of what is being reported in the article.

Methods
This should be divided into subsections if several methods are described

Results and Discussion
The Results and Discussion may be combined into a single section or presented separately.
They may also be broken into subsections with short, informative headings.

Conclusions
This should state clearly the main conclusions of the research and give a clear explanation of
their importance and relevance. Summary illustrations may be included.

Acknowledgements
These should be included at the end of the text and not in footnotes. Personal
acknowledgements should precede those of institutions or agencies.

Abbreviations
Abbreviations should be follow SI symbols and those recommended by the IUPAC.
Abbreviations should be defined in brackets after their first mention in the text. Standard
units of measurements and chemical symbols of elements may be used without definition in
the body of the paper.

References
The references should include only articles that are published or in press. The references are
each numbered, ordered sequentially as they appear in the text. Citations in the reference list
should contain all named authors, regardless of how many there are.

Please use the following style for references:
Article in a Journal:
1. Pan GJ, Chang ZY, Scholer HR, Pei DQ. Stem cell pluripotency and transcription factor
Oct4. Cell Res 2002; 12:321-329.

Chapter in a Book:
2. Hirsimaki P, Arstuka AU, Trump BF, Marzella L. Autophagocytosis. In: Trump BF,
Arstuka AU, eds. Pathobiology of cell membranes. New York: Plenum Press, 1983:201-236.

A book:
3. Kryger M, Roth T, Dement W, eds. The Principles and Practice of Sleep Medicine. 2nd
Edition. Philadelphia:WB Saunders, 1994.

Online Publication:
4. Jelinic P, Stehle JC, Shaw P. The testis-specific factor CTCFL cooperates with the protein
methyltransferase PRMT7 in H19 imprinting control region methylation. PLoS Biol 2006; 4:
e355. DOI: 10.1371/journal.pbio.0040355.

Article within a journal supplement:
5. Orengo CA, Bray JE, Hubbard T, LoConte L, Sillitoe I. Analysis and assessment of ab
initio three-dimensional prediction, secondary structure, and contacts prediction. Proteins
1999, 43(Suppl 3):149-170.

In press article:
6. Kharitonov SA, Barnes PJ. Clinical aspects of exhaled nitric oxide. Eur Respir J, in press.

Published abstract:
7. Zvaifler NJ, Burger JA, Marinova-Mutafchieva L, Taylor P, Maini RN. Mesenchymal
cells, stromal derived factor-1 and rheumatoid arthritis [abstract]. Arthritis Rheum 1999,
42:s250.

Article within conference proceedings :
8. Jones X: Zeolites and synthetic mechanisms. In Proceedings of the First National
Conference on Porous Sieves: 27-30 June 1996; Baltimore. Edited by Smith Y. Stoneham:
Butterworth-Heinemann; 1996:16-27.

Whole issue of journal :
9. Ponder B, Johnston S, Chodosh L (Eds). Innovative oncology. In Breast Cancer Res 1998,
10:1-72.

Whole conference proceedings :
10. Smith Y (Ed): Proceedings of the First National Conference on Porous Sieves: 27-30 June
1996; Baltimore. Stoneham: Butterworth-Heinemann; 1996.

Monograph or book in a series:
11. Hunninghake GW, Gadek JE. The alveolar macrophage. In Cultured Human Cells and
Tissues. Edited by Harris TJR. New York: Academic Press; 1995:54-56. [Stoner G (Series
Editor): Methods and Perspectives in Cell Biology, vol 1.]

PhD thesis:
12. Kohavi R. Wrappers for performance enhancement and oblivious decision graphs. PhD
thesis. Stanford University, Computer Science Department; 1995.

Link / URL:
13. The Mouse Tumor Biology Database [http://tumor.informatics.jax.org/mtbwi/index.do]

Preparing illustrations and figures

Figures and images should be labeled sequentially, numbered and cited in the text. Figures
should be referred to specifically in the text of the paper but should be embedded within the
text. The legends should be included from the main manuscript text file and being a part of
the figure file (using Arabic numerals, maximum figure title is 15 words and detailed legend,
up to 300 words). The use of three-dimensional histograms is strongly discouraged when the
addition of the third dimension gives no extra information. The following file formats can be
accepted:
PDF (also especially suitable for diagrams)
PNG (preferred format for photos or images)
Microsoft Word (figures must be a single page)
PowerPoint (figures must be a single page)
TIFF
JPEG

Preparing tables

These should be should be numbered in sequence using Arabic numerals (i.e. Table 1, 2, 3
etc.). Tables should also have a title that summarizes the whole table, maximum 15 words.
Table should be embedded into the text file but in portrait format (note that tables on a
landscape page must be reformatted onto a portrait page or submitted as additional files).

Preparing additional files

Supplementary information is peer-reviewed material directly relevant to the conclusion of an
article that cannot be included in the printed version owing to space or format constraints.
Any additional files will be linked into the final published article in the form supplied by the
author, but will not be displayed within the paper. They will be made available in exactly the
same form as originally provided.
If additional material is provided, please list the following information in a separate section
of the manuscript text, at the end of the document text file:
File name
File format (including name and a URL of an appropriate viewer if format is unusual)
Title of data
Description of data

Submission Preparation Checklist
As part of the submission process, authors are required to check off their submission's
compliance with all of the following items, and submissions may be returned to authors that
do not adhere to these guidelines.
1. The submission has not been previously published, nor is it before another journal for
consideration (or an explanation has been provided in Comments to the Editor).
2. The submission file is in Microsoft Word, RTF, or WordPerfect document file format.
3. Where available, URLs for the references have been provided.
4. The text is single-spaced; uses a 12-point font; employs italics, rather than underlining
(except with URL addresses); and all illustrations, figures, and tables are placed
within the text at the appropriate points, rather than at the end.
5. The text adheres to the stylistic and bibliographic requirements outlined in the Author
Guidelines, which is found in About the Journal.
6. If submitting to a peer-reviewed section of the journal, the instructions in Ensuring a
Blind Review have been followed.

Privacy Statement
The names and email addresses entered in this journal site will be used exclusively for the
stated purposes of this journal and will not be made available for any other purpose or to any
other party.

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