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I nternational J ournal of Universal Pharmacy and Bio Sciences 3(3): May-J une 2014 INTERNATIONAL JOURNAL OF UNIVERSAL PHARMACY AND BIO SCIENCES IMPACT FACTOR 1.89*** ICV 5.13*** Bio Sciences Research Article !!!
STUDY OF VAGINAL HYSTERECTOMY FOR NON DESCENT UTERUS Dr. Sowmya.K.* 1 , Dr. Ramalingappa Antartani 2
1 MBBS,MS(O.B.G),D.N.B., Assistant Professor, Department of OBG, JSS Medical College and research institute, Mysore,Karnataka, INDIA 2 MBBS,M.D,D.N.B., Professor and unit chief, Department of OBG, Karnataka Institute of Medical sciences, Hubli.
KEYWORDS:
Vaginal hysterectomy; Non descent uterus, Debulking technique. For Correspondence: Dr. Sowmya.K.* Address: MBBS,MS(O.B.G), D.N.B., Assistant Professor, Department of OBG, JSS Medical College and research institute, Mysore,Karnataka, INDIA. Email: sowsheshu@gmail.com
ABSTRACT Aim: To study feasibility of vaginal hysterectomy for non-descent uterus. Methods: A prospective study of 1 year from October 2005 to September 2006 was conducted in Karnataka institute of medical science, Hubli. In this study, 60 patients requiring hysterectomy for benign gynecological disorders who did not have any uterine descent were recruited for this study. NDVH was performed in mobile uterus, up to 14 weeks size, and with adequate vaginal access. Various debulking techniques like bisection of uterus, enucleation of fibroid, myometrial coring were used to deliver the uterus. Results: Total of 60 cases of hysterectomy was done through vaginal route. Mean age of patient was 38.0 yrs, with parity between Para II and IV, 10 cases (16.6%) were obese. Main indication for hysterectomy was fibroid uterus (31.6%).Average size of uterus 10-12 wks. Debulking technique was used in 37(38%). Average time taken was 40 min. Average blood loss was 100ml .Post operatively patients were comfortable and discharged on 3 rd post-operative day. Conclusion: Vaginal hysterectomy for non- descent large uterus is safe and feasible when it is combined with debulking techniques. 30 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
INTRODUCTION: Although hysterectomy can be done by abdominal or vaginal or laparoscopic route, 70% of these operations and in a few centers as many as 85% are done abdominally. The ease and convenience with which hysterectomy can be performed through a wide open abdominal incision, plus lack of technical expertise, with confounded fear of failure of procedure when hysterectomy is done by vaginal route has led many to continue to perform abdominal hysterectomy for non-descent uterus. The need of the hour is the minimally invasive surgery leading early to discharge from hospital, early resumption of work, scar less surgery. Though laparoscopy assisted vaginal hysterectomy (LAVH) and total laparoscopic hysterectomy (TLH) is gaining more popularity, it is associated with higher cost 1 , longer duration of operation, and need for specially trained personnel. Vaginal hysterectomy in larger sized uterus is facilitated by bisection, myomectomy, bisection, coring and clampless approach. 2 The purpose of this study is to evaluate the advantages of vaginal hysterectomy and to analyze technical feasibility of vaginal hysterectomy when combined with various debulking techniques. MATERIAL AND METHODS The present study was undertaken in Department of Obstetrics and Gynaecology, Karnataka Institute of Medical Sciences, Hubli from Oct 2005 to Sep 2006 In this study, 60 cases of vaginal hysterectomy by Modified Heaney's technique were studied pre- operatively, intra-operatively and post-operatively in detail and analyzed. Follow up of these patients was done from one to six months. Cases with non-prolapsed benign pelvic conditions having a uterine size ranging from NORMAL TO FOURTEEN weeks of gestational size were selected in this series. Patients were selected irrespective of age/ parity/ associated medical disorders, history of previous laparotomy/ obesity etc. Uterine size in these patients varied between normal sizes to fourteen weeks of gestational size. Trial of vaginal hysterectomy was given in two cases wherein the uterine size was between 12-14 weeks size and successfully completed the hysterectomy, through vaginal route in both the cases Uteri more than 14 weeks size, with restricted uterine mobility, with difficult vaginal access, complex adnexal pathology were excluded from study. Complete evaluation of the cases was done thoroughly pre-operatively, before posting the patient for surgery. In doubtful cases regarding the uterine size and mobility and associated adnexal pathology, the vaginal hysterectomy was decided after examining the patient under anesthesia. Salpingo-oophorectomy and other necessary operations for associated conditions were done, where ever it was feasible. Procedure: All cases were done under regional anaesthesia, either spinal or epidural. After cleaning and draping, cervix was held with volsellum. Saline infiltration was done in all cases. Anterior incision was made at 31 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
cervicovaginal junction .The pubo-vesico-cervical ligament was cut and bladder mobilized upwards. Both anterior and posterior pouches were opened one after another. Uterosacral and cardinal ligaments were clamped, cut and ligated. Clamping of uterine vessels was done bilaterally. Next in bigger sized uterus debulking techniques like uterine bisection, morcellation, myomectomy or combinations of these were performed as and when required. In case of fibroid with bigger sized uterus bisection was done after ligating the uterine arteries and myomectomy was done to ease limitation of space for further proceedings. In case of fundal fibroid only those myomas were removed which were interfering with delivery of the fundus. In total hysterectomy, last clamp was on uterine cornu containing round ligament, ovarian ligament and medial part of fallopian tube. To remove ovaries, round ligament was clamped separately followed by clamping of infund ibulopelvic ligament. After delivery of the uterus (with ovaries) hysterectomy was completed in usual fashion. Data regarding age, parity, uterine size, intraoperative debulking technique used, estimated blood loss, length of operation, complications and hospital stay were recorded. All patients received 3 doses of prophylactic injectable antibiotics. Postoperative catheterization with foleys catheter was done in all cases for 24 hours. Patients were followed up from 4 weeks to 6 months Results AGE INCIDENCE Table 1: Age Incidence Number of Cases According To Age Group Age in years Present study (60) 25-30 4 31-40 25 41-50 26 51-60 5 61-70 - The youngest patient who got operated was 25 years and oldest was of 60 years .41% (25) of the patients were between 31 to 40 years and mean age was 38.05 years Table 2: Parity Distribution of cases according to parity Parity Total no of cases(n=60) Nulliparous 1 1.6% Para-I 8 13.3% Para-II 10 25% Para-III 14 16% Para-IV 27 45%
In our series, 51(86) of the patients were between para II to para V and one patient was nulliparous. Incidence of obesity was 10 cases (16.6%) in our series. 32 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
Table 3:- History of previous laparotomy
In our series there were 2(3%) cases who had previous history of laparotomy. (Caesarean section (L.S.C.S)) In our series 40(68%) cases had undergone minilap tubectomy and 3(6%) patients had undergone laparoscopic sterilization. Table 4: Size of the uterus Distribution of the cases according to the size of the uterus Cases (n=60) Normal 24 40% 6 weeks 12 20% 7-8weeks 4 6.6% 9-10weeks 9 15% 11-12weeks 5 8.3% 13-14 weeks 2 3.3% 14-16wks 4 6.6%
In our series, in 40 (66%) patients the uterine size was normal to bulky. These cases were easy and ideal to operate through vaginal route. In 9 (15%) cases, uterine size was 8-10 weeks and in another 7 cases (11.6%) the uterine size varied between 10-14 weeks size. The maximum size of the uterus that was operated in our series was 14 weeks. Table 5: Main indications for vaginal hysterectomy Indication Total (n=60) Fibroid uterus 19 31.6% DUB 49 48.3 Adenomyosis 4 6.6% Chronic cervicitis 6 10% Myomatous polyp 3 5% Cervical dysplasia
Major indications for vaginal hysterectomy in our series were fibroid uterus (31.6%) and D.U.B (49%). 6(10%) had chronic cervicitis, 4(6.6%) had adenomyosis and 3(5%) fibroid polyp. Cases Percentage total (60) 2 3.00% 33 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
Table 6: Debulking technique Surgical Procedure Total (n=60) Removal of intact uterus 37 61.6% Bisection of uterus 12 20% Bisection with the enucleation of myoma 10 16.6% Morcellation / wedge resection 1 1.6%
In our series 37 (61.6%) of uterus were removed intact. Bisection of the uterus was done in 12 (20%) of the cases. Bisection with enucleation of myoma was done in 10 (16.6%),morcellation was done in 1 case (1.6%). In our series there was no case of laparotomy. There was no difficulty in delivering the uterus in 47 (87.5%) cases. In the remaining cases there was slight difficulty in delivering the uterus because of obesity, large uterus and narrow vaginal space. There was no bladder, ureteric, Intestinal and renal injuries. Average blood loss was 100ml. In 10 (16.6%) cases there was moderate amount of blood loss, where in the duration of the surgery was prolonged and the uterine size was big. In no case was blood loss severe. Average time taken was 40 minutes. Only 2 patients required 60 or more minutes. Table 7:- Associated operations done Distribution of cases according to the associated operations done Associated operation Our series (60) Posterior colpoperineorrhaphy 01 1.6% One or both tubes removed 2 3.3% One or both ovaries removed 2 3.3% Plastic operation on urethra for incontinence - -
In our series 1(1.6%) posterior colpoerineorrhaphy was done, 2(3.3%) patients had unilateral salpingo- ovariotomy and 2(3.3%) patients had bilateral salpingo-ovariotomy. (11.6%) patients had febrile morbidity out of which 3 were due to urinary tract infection and in 1 (1.6%) it was due to right upper limb thrombophlebitis and in one case the cause of the fever could not be identified. Patients were ambulatory on the 2nd post-op day. Patients were comfortable post-operatively due to less intensity of pain and required less sedation and analgesics.49(83%) of the patients were discharged on 5 days though fit to be discharged on the 3 rd day due to patient compliance. There was no mortality in our 34 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
series. On follow up 2 patients had per vaginal spotting due to granulation tissue and were treated successfully with chemical cauterization (copper sulphate). Discussion: Vaginal hysterectomy is usually avoided by many surgeons in absence of significant uterovaginal prolapse, presence of uterine enlargement, adhesions and when there is need for oophorectomy. With adequate vaginal access, vaginal hysterectomy can be easily performed. Multiparity, lax tissues following multiple deliveries and decreased tissue tensile strength provide comfort to vaginal surgeon even in the presence of uterine enlargement. Even in nulliparous with minimal descent the uterosacral and cardinal ligaments are situated in close proximity to the vaginal vault once clamped and cut produce first degree descent. Varma et al. 3 considered vaginal hysterectomy to be technically easier because of the small cervical and uterine size in nulliparous women .In a study by Aubert Agostini etal 4 out of fifty-two nulliparous patients hysterectomy was successfully done in 96.2% of cases. But they noted increased operative time and complications in these patients. Our study included only one patient in which hysterectomy was successfully completed without much difficulty. In our series there were 2(3%) cases who had previous Caesarean section (L.S.C.S).In study by SS Sheth 5 out of 200 cases vaginal hysterectomy was done in all except 3 cases. In case of R. Rajan et al 6 , series there was history of laparotomy in 49(14.54%) cases. History of previous laparotomy per se is not a contraindication for vaginal hysterectomy. It is the mobility and size of the uterus which decides the route of surgery.In our series; we had no problem in doing vaginal hysterectomy in these patients. The other important reason for lower proportion of hysterectomies performed vaginally is presence of uterine enlargement with leiomyomas or adenomyosis. According to Mazdisnian F et al 7 bulky uteri can be dealt with various debulking techniques. In our study, 60 patients without descent, In 9 (15%) cases, uterine size was 8-10 weeks and in another 7 cases (11.6%) the uterine size varied between 10-14 weeks size. The maximum size of the uterus that was operated in our series was 14 weeks. In our series 37 (61.6%) of uterus were removed intact. Bisection of the uterus was done in 12 (20%) of the cases. Bisection with enucleation of myoma was done in 10 (16.6%),morcellation was done in 1 case (1.6%). In Unger et al 2 series 30 women with uterine enlargement between 200 to 700 gm underwent various debulking procedures.Kumar and Antony 8 successfully carried out vaginal hysterectomies in 95% (76/80) and 60 of their patients needed morcellation or hemisection or myomectomy. They consider vaginal hysterectomy safe upto 12 weeks size. Das and Sheth 9 use ultrasongraphic calculation of uterine volume for assessing the feasibility of vaginal hysterectomy. They needed debulking for uteri with a volume of more than 35 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
300cm3.We were successful in removing uterus upto 14 weeks size without increase in intraoperative complications. With experience even uterus of larger size can be operated vaginally. It has been demonstrated that ovaries are visible and accessible to transvaginal removal in most cases 10 . In our series, 2(3.3%) patients had right salpingo-ovariotomy and 2(3.3%) patients had left salpingo-ovariotomy. In the Heaneys series 11 268 (47.43%) patients had undergone posterior colpoperineorraphy and in 103 (18.21%) patients either unilateral or Bilateral salpingectomy was done. The length of hospital stay reported by Dorsey JH et al 12 was 3.5 and 4.5 days for total vaginal and total abdominal hysterectomy respectively. In our series hospital stay was 3 days. In our series in 30(50%) cases, the surgery was completed within 30 minutes. In 17(28.3%) cases the time required was 45 mins. and in 14(23.3%) patients 60 mins. Only 2 patients required 60 or more minutes. This depends on the experiences of the surgeon, uterine size, and uterine mobility. In Dewan et al 13 mean operative time was 54.5 min (range 45-150 min). In Anthony ZK 8 series average time taken was 81.32min with where the uterine size varied between 14-18 wks. Conclusion: For properly selected patients with confirmed indications, vaginal hysterectomy is the preferred route in the hands of experienced surgeons who are well-versed with the vaginal surgery. . A combination of debulking techniques is often needed and the surgeon needs to be familiar with them. The need of the hour is minimally invasive surgery, early discharge from the hospital, early resumption of work, avoidance of disfiguring scar on the abdomen and cost-effectiveness of the procedure are as important as cure of the disease. Vaginal hysterectomy fulfills these criteria to absolute satisfaction. REFERENCES 1. Meikle SF, Nugent SW, Oleans M. Complications and recovery from laparoscopy assisted vaginal hysterectomy compared with abdominal and vaginal hysterectomy. Obstet GynecoI.1997; 89: 304-11. 2. Unger JB. Vaginal hysterectomy for the woman with moderately enlarged uterus weighing 200 to 700 grams. Am J Obstet Gynecol.1999; 180: 1337-44. 3. Varma R, Tahseen S, Lokugamage AU, Kunde D. Vaginal route as the norm when planning hysterectomy for benign conditions: change in practice. Obstet Gynecol 2001;97: 613616. 4. Aubert Agostini * , Florence Bretelle,Ludovic Cravello, Anne Sophie Maisonneuve, Valrie Roger andBernard Blanc .Vaginal hysterectomy in nulliparous women without prolapse: a prospective comparative study. BJOG: An International Journal of Obstetrics & Gynaecology Volume 110, Issue 5, pages 515518, May 2003. 36 | P a g e International Standard Serial Number (ISSN): 2319-8141 Full Text Available On www.ijupbs.com
5. S S Sheth, A N Malpani. . Vaginal hysterectomy following previous cesarean section. International Journal of Gynecology and Obstetrics, 1995; 50(2) 165169 . 6. R. Rajan, Linnse Eapen Ajaha Kumari, Ps Robmini and T.A Mary. Vaginal hysterectomy.The jr of obst and Gynacology of India 1983; 33:82-86. 7. Mazdisnian F 1 , Kurzel RB, Coe S, Bosuk M, Montz F. Vaginal hysterectomy by uterine morcellation: an efficient, non-morbid procedure.Obstet Gynecol. 1995 Jul;86(1):60-4. 8. Kumar S, Antony ZK. Vaginal hysterectomy for benign nonprolapsed uterus initial experience. J Obstet Gynecol Ind. 2004; 54: 60-3. 9. Das S, Sheth S. Uterine volume: an aid to determine the route and technique of hysterectomy. J Obstet Gynecol Ind. 2004; 54: 68-72. 10. Kovac SR, Cruikshank SH.Guidelines to determine the route of oophorectomy with hysterectomy. Am J Obstet Gynecol, 1996; 1483-88. 11. Heaney N. S. A report of 565 vaginal hysterectomies performed for benign pelvic disease. Am Jr of obstet and gynaecol 1934; 28:751-755. 12. Dorsey JH,Steinberg EP,Holtz PM,Clinical indications for hysterectomy route: patient characteristics or physician preference Am J Obstet Gynecol. 1995; 173 (5): 1452-60. 13. Dewan Rupali, Agarwal Shivani et al. Non descent vaginal Hysterectomy-An experience. Jr Obstet Gynecol Ind 2004; 54:376-378.
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