Académique Documents
Professionnel Documents
Culture Documents
Men (N = 229,119)
2 or 3 Cups
No Coffee
1 Cup
61.1
56.465.7
91.1
46.3
83
53
26.4
8.4
4.8
6.3
24.8
7.5
1869
63.5
58.667.2
91.1
46.3
85.5
46.7
26.5
8.6
6.5
10.4
21.3
7.5
1830
62.5
57.766.5
95.1
48.2
86.4
46.6
26.6
8
10.9
12.7
20.5
6.6
1882
1.5
1.9
33.1
25.8
59.6
1.4
1.9
34.6
26.1
58.2
1.2
1.9
36.5
26
58.1
Cause of Death
All
All causes
Participants
No. of deaths (%)
33,731
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Cancer
No. of deaths (%)
13,402
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Heart disease
No. of deaths (%)
8,127
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Respiratory disease
No. of deaths (%)
2,512
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Stroke
No. of deaths (%)
1,327
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Injuries and accidents
1729 (5.0)
1.06 (0.981.14)
1.01 (0.931.09)
712 (3.4)
1
1
1193 (3.4)
0.96 (0.871.05)
0.93 (0.851.02)
169 (0.8)
1
1
351 (1.0)
1.17 (0.971.40)
1.05 (0.871.27)
125 (0.6)
1
1
221 (0.6)
0.99 (0.801.24)
0.99 (0.791.24)
1,211
113 (0.5)
1
1
186 (0.5)
0.96 (0.761.21)
0.98 (0.771.24)
850
87 (0.4)
1
1
165 (0.5)
1.10 (0.851.42)
1.07 (0.821.39)
685
68 (0.3)
1
1
112 (0.3)
0.95 (0.701.28)
0.95 (0.701.29)
5,617
546 (2.6)
1
1
974 (2.8)
1.02 (0.921.13)
1.02 (0.921.13)
Table 3. Association of Daily Coffee Consumption with Total and Cause-Specific Mortality a
Cause of Death
All
All causes
Participants
No. of deaths (%)
18,784
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Cancer
No. of deaths (%)
7,750
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Heart disease
No. of deaths (%)
3,701
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Respiratory disease
No. of deaths (%)
1,791
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Stroke
No. of deaths (%)
966
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Injuries and accidents
No. of deaths (%)
462
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Diabetes
No. of deaths (%)
446
Age-adjusted hazard ratio (95% CI)
Multivariate-adjusted hazard ratio (95% CI)
Infections
No. of deaths (%)
448
1153 (3.8)
0.99 (0.901.08)
0.99 (0.901.08)
461 (2.2)
1
1
673 (2.2)
0.96 (0.861.08)
1.00 (0.891.13)
187 (0.9)
1
1
315 (1.0)
1.11 (0.921.33)
1.09 (0.911.31)
115 (0.6)
1
1
191 (0.6)
1.09 (0.871.38)
1.15 (0.911.45)
57 (0.3)
1
1
91 (0.3)
1.07 (0.771.49)
1.11 (0.801.55)
71 (0.3)
1
1
95 (0.3)
0.90 (0.661.22)
1.00 (0.731.36)
65 (0.3)
77 (0.3)
3,220
1
1
0.79 (0.571.10)
0.82 (0.591.15)
422 (2.0)
1
1
626 (2.1)
0.98 (0.871.11)
1.02 (0.901.16)
(N = 229,119)
Women (N = 173,141)
1 Cup
2 or 3 Cups
4 or 5 Cups
6 Cups
No Coffee
61
56.665.5
96.9
48.6
85.2
44.9
26,7
8.1
20.3
13.1
19.7
7
2007
60.3
55.964.8
97.3
48.5
83.4
37.2
26.6
8
34.7
11.6
20.6
9.3
2175
60.9
56.165.6
89.8
51.3
45.4
33.9
25.9
7.4
8.1
1.8
18.2
12.2
1444
62.9
58.166.7
87.2
51.1
46.6
31.3
25.8
7
8.8
2.3
16.6
10.2
1432
62.2
57.566.3
93.9
52.2
46.1
31
25.5
5.2
15.9
3.1
16.1
8.2
1463
1.1
1.8
38.3
24.4
57.6
0.8
1.7
40.5
21.5
55.5
1.8
2.3
25.6
28.3
68.4
52.4
1.8
2.3
25.6
30.1
67
54.8
1.6
2.2
27.1
29.5
67.6
55.3
aily Coffee Consumption with Total and Cause-Specific Mortality among 229,119 Men.*
1 Cup
2 or 3 Cups
4 or 5 Cups
6 Cups
(N = 33,961)
(N = 97,144)
(N = 32,084)
(N = 10,139)
5049 (14.9)
14,115 (14.5)
4966 (15.5)
1904 (18.8)
0.99 (0.941.03)
1.03 (0.991.07)
1.21 (1.151.27)
1.60 (1.511.69)
0.94 (0.900.99)
0.90 (0.860.93)
0.88 (0.840.93)
0.90 (0.850.96)
P Value
for Trend
<0.001
<0.001
1824 (5.4)
1.06 (0.981.15)
0.96 (0.891.04)
5804 (6.0)
1.25 (1.171.34)
1.00 (0.931.07)
2219 (6.9)
1.57 (1.461.70)
1.04 (0.961.12)
880 (8.7)
2.13 (1.952.34)
1.08 (0.981.19)
<0.001
0.02
1243 (3.7)
0.94 (0.861.03)
0.92 (0.841.01)
3353 (3.5)
0.95 (0.871.03)
0.86 (0.790.94)
409 (1.3)
1.64 (1.371.96)
0.87 (0.790.96)
185 (1.8)
2.63 (2.133.24)
0.88 (0.781.00)
<0.001
0.03
352 (1.0)
1.07 (0.891.28)
0.93 (0.771.11)
1046 (1.1)
1.21 (1.031.43)
0.83 (0.700.98)
409 (1.3)
1.64 (1.371.96)
0.83 (0.691.00)
185 (1.8)
2.63 (2.133.24)
0.81 (0.651.00)
<0.001
0.004
222 (0.7)
0.91 (0.731.14)
0.92 (0.731.15)
555 (0.6)
0.87 (0.721.06)
0.84 (0.681.02)
141 (0.4)
0.76 (0.600.97)
0.65 (0.510.84)
63 (0.6)
1.21 (0.891.64)
0.83 (0.611.14)
0.57
0.003
202 (0.6)
1.01 (0.801.27)
1.02 (0.801.29)
492 (0.5)
0.90 (0.731.10)
0.88 (0.711.09)
168 (0.5)
1.00 (0.781.26)
0.87 (0.681.12)
50 (0.5)
1.00 (0.721.40)
0.72 (0.511.02)
0.93
0.02
154 (0.5)
0.98 (0.751.27)
1.00 (0.761.31)
310 (0.3)
0.73 (0.570.92)
0.75 (0.590.96)
107 (0.3)
0.83 (0.621.10)
0.80 (0.601.08)
27 (0.3)
0.71 (0.461.10)
0.60 (0.390.94)
0.001
<0.001
124 (0.4)
0.99 (0.741.34)
1.03 (0.761.40)
276 (0.3)
0.82 (0.631.07)
0.83 (0.631.10)
80 (0.2)
0.79 (0.571.09)
0.70 (0.500.98)
25 (0.2)
0.85 (0.541.35)
0.59 (0.370.95)
0.08
0.001
928 (2.7)
0.91 (0.811.01)
0.92 (0.821.02)
2279 (2.3)
0.84 (0.760.92)
0.81 (0.740.89)
658 (2.1)
0.81 (0.730.91)
0.71 (0.630.80)
232 (2.3)
1.00 (0.861.16)
0.72 (0.610.84)
0.002
<0.001
aily Coffee Consumption with Total and Cause-Specific Mortality among 229,119 Men.*
1 Cup
2 or 3 Cups
4 or 5 Cups
6 Cups
(N = 33,961)
(N = 97,144)
(N = 32,084)
(N = 10,139)
3388 (10.8)
7140 (10.5)
2099 (12.0)
775 (15.0)
0.93 (0.880.98)
0.93 (0.890.98)
1.13 (1.071.20)
1.51 (1.391.64)
0.95 (0.901.01)
0.87 (0.830.92)
0.84 (0.790.90)
0.85 (0.780.93)
P Value
for Trend
<0.001
<0.001
1313 (4.2)
1.02 (0.931.11)
1.01 (0.921.10)
3110 (4.6)
1.14 (1.051.23)
0.98 (0.901.06)
1016 (5.8)
1.52 (1.381.67)
1.01 (0.921.12)
375 (7.3)
2.00 (1.772.27)
1.03 (0.901.16)
<0.001
0.66
683 (2.2)
0.86 (0.760.96)
0.91 (0.811.03)
1379 (2.0)
0.83 (0.750.93)
0.85 (0.760.95)
378 (2.2)
0.95 (0.831.09)
0.78 (0.680.90)
127 (2.5)
1.16 (0.951.41)
0.72 (0.590.88)
0.67
<0.001
279 (0.9)
0.85 (0.711.03)
0.84 (0.691.01)
698 (1.0)
1.03 (0.881.22)
0.79 (0.670.93)
208 (1.2)
1.29 (1.061.57)
0.65 (0.530.79)
104 (2.0)
2.35 (1.852.99)
0.77 (0.610.99)
<0.001
<0.001
168 (0.5)
0.84 (0.661.06)
0.89 (0.701.13)
369 (0.5)
0.89 (0.721.10)
0.93 (0.751.15)
91 (0.5)
0.92 (0.701.21)
0.82 (0.621.09)
32 (0.6)
1.18 (0.791.74)
0.84 (0.561.25)
0.82
0.05
114 (0.4)
1.22 (0.881.67)
1.27 (0.921.76)
153 (0.2)
0.77 (0.571.05)
0.77 (0.561.06)
36 (0.2)
0.74 (0.491.12)
0.64 (0.420.98)
11 (0.2)
0.81 (0.421.54)
0.57 (0.291.10)
0.004
<0.001
93 (0.3)
0.79 (0.581.08)
0.91 (0.671.25)
140 (0.2)
0.56 (0.420.75)
0.77 (0.571.03)
38 (0.2)
0.63 (0.420.93)
0.82 (0.541.23)
9 (0.2)
0.53 (0.271.07)
0.57 (0.281.16)
<0.001
0.03
96 (0.3)
152 (0.2)
37 (0.2)
21 (0.4)
0.88 (0.641.20)
0.93 (0.681.29
0.66 (0.500.89)
0.69 (0.510.94)
0.66 (0.440.99)
0.60 (0.400.91)
1.36 (0.832.22)
0.97 (0.581.61)
0.63
0.13
642 (2.0)
0.89 (0.791.01)
0.94 (0.831.07)
1139 (1.7)
0.76 (0.680.85)
0.79 (0.710.89)
295 (1.7)
0.81 (0.700.94)
0.74 (0.640.87)
96 (1.9)
0.96 (0.771.20)
0.72 (0.570.90)
<0.001
<0.001
= 173,141)
4 or 5 Cups
6 Cups
61.6
57.065.8
96.5
52.7
43.5
28.7
25.1
4.5
31.1
3.3
16
8.2
1540
61
56.465.3
97.2
52.6
37.8
24.3
25
4.4
48.1
3
15.4
10
1642
1.4
2.2
28.4
27.3
66.1
51.2
1.2
2
29.6
23.9
62.4
45.1