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General information
Mode of Action
It acts by rupture of cell membranes and denaturation of
cellular constituents.
Advantages
C a n be used in preservation of organic wastes.
Cheap and close effective.
Disadvantages
Too toxic to be used as an antiseptic on skin
Duration of contact must be long – 6 –12 hours.
Its activity decreases in alkaline pH.
Not compatible with cationic surface-active agents.
Clinical Information
Indications
Disinfectant for bathrooms, floors, washbasins etc.,
Waste disinfection – infective wastes such as sputum, urine,
faeces etc and body fluids can be disinfected before disposal.
Drug Toxicity
If ingested – local corrosion, pain, nausea, vomiting, sweating,
diarrhoea, CNS depression, circulatory and respiratory failure,
pulmonary edema and myocardial damage, liver and kidney
dysfunction.
Treatment of Toxicity
If swallowed, gastric lavage should be done with water and
olive oil (or another vegetable oil) to delay absorption. Activated
charcoal may be used.
If spilled on skin – remove contaminated clothing, blot off the
excess and wash skin well with copious amounts of water, followed
by a vegetable oil.
Keep the patient warm.
Supportive treatment.
Storage
Store in airtight containers. Protect from light.
Phenyl:
Phenyl is a fluid disinfectant which destroys pathogenic organism. It
is a strong deodorant and germicide for dis- infecting hospitals,
nursing homes, drains, lavatory, toilets and cowsheds, and is
extensively used for sanitation purposes.
Raw Materials:
The major raw materials required are cresylic cresote and cresol
which are phenol bearing liquids. Besides, rosin, caustic soda,
casmaterialor oil and soyabean oil are also required.
Process of Manufacturing: