GW501516 is a peptide that is considered to be a PPAR receptor agonist. It is occasionally known as GW 501!516! GW1516! G"#516! and $nd%robol. &echanics o' GW501516 According to scienti'ic research cond%cted on ani(al test s%b)ects! GW501516 acti*ates si(ilar pathways that are acti*ated thro%gh e+ercise. ,ne o' these pathways is PPAR! also known as Pero+iso(e proli'eratoracti*ated receptor delta. -his pathway is a n%clear hor(one receptor in ani(al test s%b)ects that r%les o*er a host o' biological processes and (ay ha*e a role in *ario%s chronic diseases s%ch as obesity! atherosclerosis! diabetes! and cancer. It is belie*ed to work at the gene le*el and a''ects the (etabolis( o' skeletal (%scle Another one o' the pathways the peptide acti*ates is A&Pacti*ated protein kinase! which is an en.y(e that plays a role in cell%lar energy ho(eostasis in ani(al test s%b)ects. GW50156 acts as a selecti*e acti*ator o' the PPAR receptor beca%se it shows high a''inity and potency 'or the pathway. In ani(al test s%b)ects s%ch as rats! the binding o' the peptide to this partic%lar receptor recr%its the coacti*ator PG/10. In t%rn! this coacti*ator %preg%lates the e+pression o' proteins associated with energy e+p%lsion. -his! in t%rn! led to the scienti'ic theory that the peptide co%ld increase (%sc%lar strength and end%rance in ani(al test s%b)ects. Addtionally! the peptide showed an ability to ele*ate 'atty acid (etabolis( in skeletal (%scle 'or (eans o' protection against dietind%ced obesity! as well as an increase in gl%cose %ptake in skeletal (%scle tiss%e and an ele*ation in gene e+pression. 1%rther(ore scienti'ic research based on ani(al test s%b)ects deter(ined that the peptide co%ld ca%se an increased b%rning o' 'at witho%t e+periencing (%scle catabolis(2 that is! the set o' (etabolic pathways that breaks down (olec%les into s(aller pieces to release energy. Additionally! scienti'ic research cond%cted on ani(al test s%b)ects deter(ined that GW501516 has a synergistic e''ect when it is co(bined with AI/AR! or 5A(inoi(ida.ole3carbo+a(ide ribon%leotide. Initial Search for Positive Theoretical Benefits with GW50156 4eca%se o' the properties that GW50156 e+hibited! scienti'ic st%dy had concentrated their st%dy on ani(al test s%b)ects in order to deter(ine i' the peptide co%ld be '%rther researched as a theoretical treat(ent 'or the 'ollowing ail(ents5 ,besity 6iabetes Click here to buy G 50151! in our store 6yslipide(ia 7that is! an abnor(al a(o%nt o' lipids like cholesterol or 'at in the blood8 /ardio*asc%lar disease! %p to and incl%ding the pre*ention o' cardiac arrest Additionally! scienti'ic research cond%cted on ani(al test s%b)ects theori.ed that beca%se o' the peptide9s ability to sti(%late (%scles to b%rn 'ats instead o' s%gars! it co%ld ele*ate le*els o' :good; cholesterol 7that is! <6= cholesterol8. -his is the cholesterol that helps to red%ce the risk o' cardiac arrest. GW501516 and Cancer While scienti'ic research cond%cted on ani(al test s%b)ects had deter(ined several theoretical benefits that (ay be associated with GW501516! st%dies ha*e yielded res%lts that indicate that these theoretical bene'its are tr%(ped by the negati*e side e''ects that the peptide ind%ces. "peci'ically! scienti'ic research cond%cted on ani(al test s%b)ects has deter(ined that GW50156 has the ability to *ario%s to+icities within the body. "peci'ically! these tests ha*e yielded res%lts that point to the peptide9s capability to ca%se *ario%s (ani'estations o' cancer in a rapid! e''icient (anner. "cienti'ic st%dy on laboratory test rats had deter(ined that e+pos%re to the peptide ca%sed se*eral 'or(s o' cancers in the rats! incl%ding5 /ancer o' the skin /ancer o' the li*er /ancer o' the bladder /ancer o' the sto(ach /ancer o' the thyroid /ancer o' the tong%e /ancer o' the testes 7(ale rats only8 /ancer o' the o*aries 7'e(ale rats only8 /ancer o' the wo(b 7'e(ale rats only8 While the scienti'ic st%dy based on ani(al research s%b)ects ha*e ret%rned with research linking GW501516 to the proli'eration o' cancer! it sho%ld be noted that these tests that res%lted in these types o' associations were based on large ad(inistrati*e a(o%nts o' the peptide. For Scientific Use nl! While there ha*e been se*eral scienti'ic st%dies cond%cted on ani(al test s%b)ects in order to deter(ine GW5015169s range o' (echanis(s and negati*e side e''ects > especially those related to its association with cancer > it sho%ld be noted that any and all 'indings that are associated with the peptide are still considered to be the prod%ct o' c%rrent laboratory research. 4eca%se GW501516 l is c%rrently in the research phase! any st%dy or %sage relating to the (echanics! operations! and side e''ects o' the peptide sho%ld solely be contained to the restrictions o' a strictly controlled en*iron(ent s%ch as a library or a (edical research 'acility.