FC Path(SA) Chem

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain
Reg No 1955/000003/08

The Examination for the Fellowship of the
College of Pathologists of South Africa - Chem

22 March 2011

Paper 1 Laboratory Management and Practice (3 hours)

Answer any FOUR questions. Each question to be answered in a separate book (or books if more than one is required
for the one answer)
Beantwoord enige VI ER vrae. Elke vraag moet in aparte boek (of boeke indien meer as een nodig is vir n vraag)
geskryf word.

1 The Department of Health is currently planning to implement a National Health
Insurance (NHI) plan. Discuss in detail the effect that this would have on the
rendering of diagnostic pathology services and how you would manage these effects.
(Guideline to candidates: Take care to discuss the effects on both the private sector
as well as the National Health Laboratory Service). [25]

1 Die Departement van Gesondheid is tans besig om Nasionale Gesondheids
Versekering plan teimplimenteer. Bespreek in detail die effek so plan kan h op die
lewering van diagnostiese patologie dienste en hoe u hierdie gevolge sou bestuur.
(Riglyn aan kandidate: Neem sorg om die gevolge op beide die privaat sektor sowel
as die Nasionale Gesondheidsdiens Laboratorium Dienste (NHLS) in aanmerking
teneem). [25]


2 Discuss the various practical approaches and tools that can be used to improve
quality in the pathology laboratory. [25]

2 Bespreek die verskillende praktiese benaderings en hulpbronne wat gebruik kan
word om gehalte in die patologie laboratorium te verbeter. [25]


3 What factors and standards would you use in implementing point of care testing
(POCT) for glucose and cholesterol in health care clinics in South Africa? [25]

3 Watter faktore en standaarde sou u gebruik met die implimentering van punt van
sorg toetse (PVST) vir glukose en cholesterol in gesondheidsorg-klinieke in Suid-
Afrika? [25]






PTO/ Page-2-Question-4...

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4 2011 has been designated as the International Year of Chemistry by the International
Union of Pure and Applied Chemistry (IUPAC) and the United Nations Educational
Scientific and Cultural Organisation (UNESCO). Outline the major achievements in
the field of Clinical Chemistry over the past 40 years (1971 2011). [25]

4 Die International Union of Pure and Applied Chemistry (IUPAC) en die Verenigde
Nasies se Educational Scientific and Cultural Organisation (UNESCO) het 2011
geoormerk as die jaar internationale van Chemie. Beskryf die grootste mylpale wat
bereik is in die afgelope 40-jaar in die veld van Kliniese Chemie (1971 2011). [25]


5 Discuss the following statement The quality of evidence and strength of
recommendations for diagnostic tests seems to be becoming more important in
defining diagnostic strategies. (25)

5 Bespreek die volgende stelling Die gehalte van bewyse en die sterkte van
aanbevelings vir diagnostiese toetse word waarskynlik van al groter belang in die
definiring van diagnostiese strategie. [25]
































FC Path(SA) Chem

THE COLLEGES OF MEDICINE OF SOUTH AFRICA
Incorporated Association not for gain
Reg No 1955/000003/08

The Examination for the Fellowship of the
College of Pathologists of South Africa - Chem

23 March 2011

Paper 2 Applied Clinical Biochemistry (3 hours)

Answer any FOUR questions. Each question to be answered in a separate book (or books if more than one is required
for the one answer)
Beantwoord enige VI ER vrae. Elke vraag moet in aparte boek (of boeke indien meer as een nodig is vir n vraag)
geskryf word.

1 Critically discuss the use of cardiac troponin in the diagnosis of acute coronary
syndrome, also refer to other conditions than acute coronary syndromes and heart
failure which may cause an increase in cardiac troponins. [25]

1 Bespreek krities die gebruik van kardiale troponien in die diagnose van akute
koronre sindroom, verwys ook na ander toestande as akute koronre sindrome en
hartversaking wat verhoging van kardiale troponien mag veroorsaak. [25]

2 Discuss the pathophysiology of excessive peritoneal fluid formation (ascites) and the
diagnostic pathology tests which should be performed on such fluids. [25]

2 Bespreek die patofisiologie van die vorming van oormatige peritoneale vog (askitis)
en die diagnostiese patologie ondersoeke wat uitgevoer moet word op
peritoneale vog. [25]

3 You are employed as the new Chemical Pathologist at a hospital with a busy
emergency department. Your main responsibility is to establish a laboratory for the
diagnosis and management of patients with acute poisoning. Discuss your approach.
[25]

3 U is in diensgeneem as die nuwe Chemiese Patoloog by hospitaal met besige
ongevalle department. U hoof verantwoordelikheid is om laboratorium daar te stel
vir die diagnose en bestuur van pasinte met akute vergiftiging. Bespreek u
benadering. [25]

4 Critically discuss the use of haemoglobin A1c (HbA1c) in the diagnosis of diabetes
and pre-diabetes. [25]

4 Bespreek krities die gebruik van hemoglobien A1c (HbA1c) vir die diagnose van
diabetes en pre-diabetes. [25]



PTO/-Page-2-Question-5...
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5 Discuss the challenges and pitfalls of plasma protein standardisation and the
success achieved to date. [25]

5 Bespreek die uitdagings en struikelblokke van plasma protin standardisasie en die
sukses wat tot dusver daarmee behaal is. [25]