..................................................................................HN..

Naranjo's algorithm:
.. .. ..
...

1.

+1

2.

3.
(specific antagonist)
4.

5. ()

+2

-1

+1

+2

-1

-1

+2

6.

-1

+1

7. ()

8.

9.

10.
(objective evidence)

+1

+1

+1

+1

Definite

5-8

Probable

1-4

Possible

Doubtful

.....................................
........................................

 Naranjo's algorithm

1.

Naranjo,s algorithm 1 1 1

2.

Naranjo,s algorithm 10 "" "" ""

1 "Doubtful" ()
1-4 "Possible" ()
5-8 "Probable" ()
8 "Definite" ()

3.

() Naranjo's
algorithm
Naranjo's algorithm

1
:

:
(1) Penicillin = +1
(2) = 0
(3) = 0
2
:
:
penicillin 10
(1) 2543 10 2543
= +2
(2)

penicillin 10 2544
9 2544 = -1

(3) = 0
3 (specific antagonist)

:

(1) penicillin penicillin
= +1

(2) penicillin penicillin
= 0
(3)

= 0

4
:
:

penicillin
(1) penicillin penicillin (
)
= +2
(2) 1 = -1
(3)

= 0

5 ()
: ( ()

:

(1) cisparide
= -1
(2)

= +2

(3)

= 0

 6 (placebo)
:

:
(1) = -1
(2) = +1
(3)

= 0

7 ()
: ()

:

digoxin
(1)
digoxin 2 ng/ml
= +1
(2)

1 2
ng/ml = 0

(3) = 0
8
:
:
(1)

digoxin = +1

(2)

1 digoxin
= 0

(3)

= 0

9
:

penicillin
(1)
penicillin
= +1
(2)

1 penicillin
= 0

(3)

= 0

10 (objective evidence)
:
EKG
:
(1)
AST, ALT
= +1
(2)

1 AST, ALT
= 0

(3) = 0