RevistaBolivianaDeQuímica

Rev. Bol. Quim.

Vol. 26, No. 1, 2009
Abstracts Résume

E VALUACION DE LA FLORA EN EL VALLE DE ZONGO CONTRA LEISHMANIA Y

CHAGAS
Sandra L. Ibáñez-Calero, Grace Ruiz, Rosaura de Michel, Michel Sauvain Página 1

Keywords: Native Flora, Zongo Valley, Bolivia, Leishmaniasis, Chagas’ disease

ABSTRACT

Tropical diseases caused by protozoan produce great suffering in developing countries and result in high
morbidity and mortality rates. Among these illnesses, Leishmania and Chagas are of importance. Leishmania
consists in a critical heath problem for the social and economical consequence that result. Due to these aspects,
WHO has classified leishmaniasis, along with African tripanosomiasis and denge, within category 1 for the
research of new prevention methods, diagnosis and treatment [1]. In addition, the same organization has
classified Chagas disease as the third most important worldwide tropical illness due to its severity and mortality
[2]. Botanical collects sort by altitude in the Valley of Zongo, Bolivia, have presented two species with important
activities. The specie Bocconia integrifolia ( Papaveraceae) with un IC50 of 6 µg/ml against Chagas and 0.4
µg/ml against three strains of leishmania and the specie Liabum hastifolium (Compositae) with un IC50 of 10.4
µg/ml against three strains of leishmania.

Corresponding author: caleros@acelerate.com

A ISLADOS PROTEÍNICOS DE GRANOS ALTOANDINOS CHENOPODIACEAS; QUINUA

“CHENOPODIUM QUINOA” – CAÑAHUA “CHENOPODIUM PALLIDICAULE” POR
PRECIPITACIÓN ISOELÉCTRICA
J. Carlos Callisaya A., J. Antonio Alvarado K. Página 12

Keywords: Quinoa, Canihua, Protein isolate, Protein solubility

ABSTRACT

The quinoa (Chenopodium Quinoa Willd) and the canihua (Chenopodium Pallidicaule Aellen), pseudocereals of
the region of the Andes of South America, report an exceptional composition of amino acids. Considering these
antecedents this study has the purpose of to isolate and to optimize the extraction effects and precipitation of the
proteins in the point isoeléctrico in two quinoa varieties and canihua, respectively. The isolated proteic got ready
by means of the extraction to pH 8,0 - 8,9 to protect the material proteic of the oxidation, an antioxidant was
added in the extract watery sulphite of sodium 0,1% p/p and precipitation of the proteins to pH 4,5 at 5,3. The
content of proteins is of 85,86; 83,60; 87,74; 82,68% for QIK, QST, CAK, CVT respectively with a humidity of
7,71; 8,11; 7,59; 8,10 for CVT, CAK, QIK and QST respectively, value relatively low that confer stability in the
time. The solubility of the isolated proteic increases until the 45 ºC and diminish above the 45 ºC observed the
denaturalization of the protein. The solubility of the proteins to pH 4,5 are smaller, being observed a higher
solubility to pH different from the point isoelectric, what shows us that the method applied in the obtaining and
optimization of the isolated quinoa proteic and canihua is adapted.

Corresponding author: jaalvkir@gmail.com

A 5-METHYLCOUMARIN GLUCOSIDE AND A COUMESTAN DERIVATIVE FROM

MUTISIA ORBIGNYANA
Yonny Flores, Gloria Rodrigo, Patricia Mollinedo, Bjorn Akesson, Olov Sterner, Giovanna R. Almanza Página 21

Keywords: Mutisia orbignyana; Compositae; coumarins, antiproliferative capacity; scavenging effect; Bolivian medicinal
plants

ABSTRACT

The ethanolic extract of the aerial parts from Mutisia orbignyana afforded two major compounds:
mutisifurocoumarin (1) and 5-methylcoumarine-4-β-glucoside (2). The completely assignment of 1H and 13C
NMR data of compound (2) is presented for the first time as well as some reassignments of 13C NMR spectrum
for compound (1), applying 2D NMR techniques. In addition, the antiproliferative effect on colon cancer cells
(CaCo2) and the scavenging effect using the ABTS test were measured The results showed an interesting
scavenging activity and a non proliferative effect on colon cancer cells.

Corresponding author: giovyalmanza@yahoo.com.ar

EL PRODUCTO DE LA REACCION DE STENHOUSEN COMO COLORANTE PARA EL

RECONOCIMIENTO DE LA POLIAMIDA
Willy J. Rendón P. Página 27

Keywords: colorante, poliamida, tinción

ABSTRACT

The pink product of the J. Stenhousen reaction was used for colouring fibres such as cotton, polyester, white
cardboard, newspaper, silk paper, bond paper, filter paper, Dacron, wool’s sheeps, plastoform, polyamide,
viscous rayon, polymeric rayon, and alpaca’s wool. Polyamide fibres posses affinity for the Stenhousen’ reaction
product being coloured of intense pink, therefore allowing to recognize the polyamide among all other used
materials, as it can be observed in Tabla Nº 3

Corresponding author: willyjrendon@yahoo.com

COMPLEX FORMATION OF SOME DIVALENT METAL IONS WITH OXYGEN DONOR

LIGANDS
Brij B. Tewari Página 30

Keywords: Paper electrophoretic technique; overall mobility; beryllium(II) complexes; cobalt(II) complexes; α-
aminobutyric acid, stability constant
ABSTRACT

Complexation reaction of α-aminobutyric acid with beryllium(II) and cobalt(II) have been studied in solution
phase using paper electrophoretic technique. This method is based on the movement of a spot of metal ion in an
electric field at various pH’s of the background electrolyte. A plot of overall mobility of metal / complex ion
versus pH was used to obtain information on the binary complexes and to calculate stability constants. The
stability constant of the ML and ML2 complexes of beryllium(II) - α-aminobutyric and cobalt(II) - α-
aminobutyric acid have been found to be (7.19 ± 0.05, 6.81 ± 0.13) and (4.47 ± 0.04, 2.81 ± 0.09) (logarithm
stability constant values), respectively at 35°C and ionic strength 0.1 M

Corresponding author: brijtew@yahoo.com

E STUDIO COMPARATIVO DE LA ADSORCIÓN DE NITRÓGENO SOBRE NANOCONOS

Y NANOTUBOS DE CARBÓN
Alberto G. Albesa, José L. Vicente Página 37

Keywords: Nanoconos, nanotubos, adsorción, calor isostérico, mecanismo

ABSTRACT

We studied the adsorption of nitrogen on nanostructures of carbon with cylindrical (nanotubes) and conical
(nanocones) geometries, when their ends are open or closed. It was found that the adsorption capacity of open
nanotubes is more than in the open nanohorns. Calculations of the isosteric heat of adsorption were performed for
both structures and it appears that, it is smaller for nanocones than for nanotubes in case that both are closed, on
the entire range of pressures. For open structures at low pressure the isosteric heat of adsorption is greater for
nanoconos than for nanotubes, and increasing the pressure, the opposite behaviour is observed

Corresponding author: albesa@inifta.unlp.edu.ar