Tumour markers knowledge

Statements
Please select True or False
True Fals
e
1. In general, serum tumour markers are rarely
elevated in patients with early malignancy
2. No single tumour marker in current use is specifc
or malignancy
!. There are tumour markers with a"solute organ
specifcity
#. $e%uesting multiple tumour markers in an
attempt to identiy the primary cancer is rarely o
value.
&. $e%uesting multiple tumour markers in an
attempt to identiy the presence o secondaries is
rarely o value.
'. (easurement o tumour markers is
recommended in patients with vague symptoms
when the likelihood o cancer is low.
Match
Please match the tumour marker with the relevant cancer letter
)one answer*
Tumour
marker
Relevant
cancer
A. +reast cancer
B. ,olorectal cancer
C. -varian cancer
D. Prostate cancer
E. (edullary thyroid
carcinoma
F. Pancreatic cancer
G. Thyroid cancer
)ollicular or papillary*
. .epatocellular cancer
!. /erm cell and testicular
cancers0 gestational
1 etoprotein
,alcitonin
,ancer
antigen 12&
),212&*
,ancer
antigen 1&3!
),21&3!*
,ancer
antigen 1434
),21434*
,arcinoem"ry
onic antigen
),52*
tropho"lastic neoplasia .uman
chorionic
gonadotrophin
Prostate
specifc
antigen )P62*
Thyroglo"ulin
A""ro"r#ate tumour marker use
Please select what is appropriate )one or more answers per row*
Currentl$ recommended cl#n#cal recommendat#ons
Tumour marker
Screen#ng
or earl$
detect#on
D#agnos#s
or case
%nd#ng
&rognos#s
'w#th other
(actors)
Detect#n
g
recurren
ce
Mon#tor#
ng
treatmen
t
1 etoprotein
,alcitonin
,ancer antigen
12& ),212&*
,ancer antigen
1&3! ),21&3!*
,ancer antigen
1434 ),21434*
,arcinoem"ryon
ic antigen ),52*
.uman chorionic
gonadotrophin
Prostate specifc
antigen )P62*
Thyroglo"ulin
Cl#n#cal "ract#ce
Please circle only one answer
1. 7o you use cancer antigen 12& to investigate ovarian cancer or a pelvic
mass "r#or to other tests )e.g. imaging*
Alwa$s Fre*uentl$ Rarel$ +a#t (or other tests %rst
,ever
2. 7o you use cancer antigen 1434 to investigate pancreatic cancer in
Progressive o"structive 8aundice with weight loss "r#or to other tests )e.g.
imaging*
Alwa$s Fre*uentl$ Rarel$ +a#t (or other tests %rst
,ever
3. 7o you use carcinoem"ryonic antigen ),52* to investigate ,olorectal
cancer in Intermittent a"dominal pain, nausea, vomiting or "leeding "r#or
to other tests )e.g. imaging*
Alwa$s Fre*uentl$ Rarel$ +a#t (or other tests %rst
,ever
4. 7o you use prostate specifc antigen )P62* to investigate prostate cancer
in Fre%uency, urgency, nocturia, dysuria0 acute retention "r#or to other
tests )e.g. imaging*
Alwa$s Fre*uentl$ Rarel$ +a#t (or other tests %rst
,ever
5. 7o you use aFP to investigate .epatocellular carcinoma or ascites "r#or
to other tests )e.g. imaging*
Alwa$s Fre*uentl$ Rarel$ +a#t (or other tests %rst
,ever
Grade- S"ec#al#t$-