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David Presti
Department of Molecular and Cell Biology
University of California, Berkeley
Summer 2008
Topics
brain and nervous system organization
atoms, molecules, proteins, lipids, membranes
cells, DNA, genes
neurons, ion channels, nerve signaling
synapse, neurotransmitters, neural circuits
molecular pharmacology, drugs
seizures
brain imaging (PET, fMRI, MEG, etc)
brain development
sensation and perception
Topics
vision
audition, music
taste, smell
somatosensory / tactile
movement, paralysis
biological rhythms, sleep, dreaming
learning, memory
language
mental disorders: depression, psychosis, etc
mind, consciousness
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Textbooks
An Introduction to Brain and Behavior
by Bryan Kolb And Ian Whishaw
2nd edition - 2006
The Double Helix
by James Watson - 1968
Norton Critical Edition
edited by Gunther Stent - 1980
Course Grade
Exams:
Two Midterm Exams (online)
Final Exam (proctored)
Homeworks:
neuroscience in the news (one)
Double Helix essay
composing exam questions
neuroscience in the news (two)
Online Discussion Forum participation
2001: A SPACE ODYSSEY
(1968)
directed by Stanley Kubrick
written by Stanley Kubrick (1928-1999)
and Arthur C. Clarke (1917-2008)
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Hominid Evolution
hominid = human-like animal
includes modern humans and recent
(circa past 4 million years)
human ancestors
a timeline of hominid evolution
millions of years ago
Figure 1-12
time spans
are
approximate
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Hominid Evolution
genus Australopithecus
various species have been described:
A. robustus, A. africanus,
A. afarensis, A. aethiopicus
circa 4 million years to 1 million years ago
Hominid Evolution
genus Homo
Homo habilis
circa 2 million years to 1.5 million years ago
Homo erectus
circa 1.6 million years to 200,000 years ago
Homo sapiens
modern humans
circa 200,000 years ago
to the present
only extant hominid species
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Homo neanderthalensis
parallel evolutionary branch of the genus Homo
circa 300,000 to 30,000 years ago
ritual
burial of dead
pet animals
music
ancient music? - circa 50,000 years ago
portion of what appears to be a flute made
from bear bone by Homo neanderthalensis
Figure 9-1
brain
size
cubic
centimeters
(cc)
Figure 1-12
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Killing of conspecifics
hominid human ancestors
~ 4 million years ago
human deaths due to violent conflict
in the 20th century
~160,000,000
I refuse to accept the cynical notion that nation after nation
must spiral down a militaristic stairway....I believe that unarmed
truth and unconditional love will have the final word in reality.
Martin Luther King (1929-1968)
Nobel Peace Prize acceptance speech - 1964
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Does HAL
have a
mind?
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What is Mind?
collection of mental states
internal, subjective experiences:
thoughts
feelings
perceptions
awareness / consciousness
Reading associated with this lecture:
An Introduction to Brain and Behavior
Chapter 1
begin reading
The Double Helix

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