1.

When trying to determine why the desired therapeutic effect is not being seen with an oral
drug, the nurse should consider:
a. the blood flow to muscle beds.
b. food altering the makeup of gastric juices.
c. the weight of the patient.
d. the temperature of the peripheral environment.

2. An example of a drug allergy is
a. dry mouth occurring with use of an antihistamine.
b. increased urination occurring with use of a thiazide diuretic.
c. breathing difficulty after an injection of penicillin.
d. skin rash associated with procainamide use.

3. A patient taking glyburide (an antidiabetic drug) has his morning dose and then does not
have a chance to eat for several hours. An adverse effect that might be expected from this
would be
a. a teratogenic effect.
b. a skin rash.
c. an anticholinergic effect.
d. hypoglycemia.

4. A patient with a severe infection is given gentamicin, the only antibiotic shown to be effective
in culture and sensitivity tests. A few hours after the drug is started intravenously, the patient
becomes very restless and develops edema. Blood tests reveal abnormal electrolytes and
elevated BUN. This reaction was most likely caused by
a. an anaphylactic reaction.
b. renal toxicity associated with gentamicin.
c. superinfection related to the antibiotic.
d. hypoglycemia.

5. Patients receiving antineoplastic drugs that disrupt cell function often have adverse effects
involving cells that turn over rapidly in the body. These cells include
a. ovarian cells.
b. liver cells.
c. cardiac cells.
d. bone marrow cells.

6. A woman has had repeated bouts of bronchitis through- out the fall and has been taking
antibiotics. She calls the clinic with complaints of vaginal pain and itching. When she is seen, it
is discovered that she has developed a yeast infection. You would explain to her that
a. her bronchitis has moved to the vaginal area.
b. she has developed a superinfection because the antibiotics kill bacteria that normally provide
protection.
c. she probably has developed a sexually transmitted disease related to her lifestyle.
d. she will need to take even more antibiotics to treat this new infection.

7. Knowing that a patient is taking a loop diuretic and is at risk for developing hypokalemia, the
nurse would assess the patient for
a. hypertension, headache, and cold and clammy skin.
b. decreased urinary output and yellowing of the sclera.
c. weak pulse, low blood pressure, and muscle cramping.
d. diarrhea and flatulence.

8. The nurse is delivering the client's 10 a.m. medications. The client is away from his room for
a diagnostic study. Which action is most appropriate for the nurse to take?
a. Leave the medications on the client's bedside table.
b. Ask the client's roommate to keep the medications for the client until he returns.
c. Lock the medications in the medicine preparation area until the client returns.
d. Have the client skip that dose of medication.

9. A child with type 1 diabetes develops diabetic ketoacidosis and receives a continuous insulin
infusion. Which condition represents the greatest risk to this child?
a. Hypercalcemia
b. Hyperphosphatemia
c. Hypokalemia
d. Hypernatremia

10. The nurse is preparing to discharge a child who has rheumatic fever. Which of the following
medications is prescribed to prevent recurrence of rheumatic fever?
a. Glucocorticoids
b. Digoxin
c. Antibiotics
d. Anti-inflammatory medications

11. Which detail of a client's drug therapy is the nurse legally responsible for documenting?
a. Peak concentration time of the drug
b. Safe ranges of the drug
c. Client's socioeconomic data
d. Client's reaction to the drug

12. The physician orders an I.M. injection for a client. Which factor may affect the drug
absorption rate from an I.M. injection site?
a. Muscle tone
b. Muscle strength
c. Blood flow to the injection site
d. Amount of body fat at the injection site

13. The nurse is to administer an I.M. injection into a client's left vastus lateralis muscle. How
should the nurse position the client?
a. Lying supine
b. Lying on the stomach
c. Lying on the left side
d. Lying on the right side

14. A client is in the bathroom when the nurse enters to give a prescribed medication. What
should the nurse do?
a. Leave the medication at the client's bedside.
b. Tell the client to be sure to take the medication, and then leave it at the bedside.
c. Return shortly to the client's room and remain there until the client takes the medication.
d. Wait for the client to return to bed, and then leave the medication at the bedside.

15. The physician prescribes a loop diuretic for a client. When administering this drug, the nurse
anticipates that the client may develop which electrolyte imbalance?
a. Hypervolemia
b. Hypokalemia
c. Hyperkalemia
d. Hypernatremia