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1. What is the most common cause of aseptic meningitis of viral etiology?

a. Enteroviruses
b. erpesviruses
c. !rboviruses
". #etroviruses
e. Orthomy$oviruses
%. &rotection against influen'a ! virus in a nonimmune in"ivi"ual can be achieve"
through the a"ministration of a "rug that interferes (ith
a. )iral en"onuclease activity
b. bin"ing of host messenger #N! *m#N!+ caps by the viral &1 protein
c. Synthesis of viral progeny #N!
". ,ncoating of nucleic aci"
e. )iral a"sorption an" penetration
-. Which one of the follo(ing immuni'ations shoul" be a"ministere" imme"iately after
birth?
a. .iphtheria/pertusis/tetanus *.&T+ vaccine
b. aemophilus influen'ae type b vaccine
c. epatitis 0 vaccine
". 1) )accine
e. Oral &olio virus
2. Which one of the follo(ing infection routes is most often involve" in the neonatal
transmission of hepatitis 0 virus *0)+?
a. 0loo" transfusion
b. 3etal contact (ith infecte" bloo" "uring chil"birth
c. 1ngestion of the virus via maternal breast mil4
". Transmission of the virus from hospital personnel "uring chil"birth
e. Transplacental transmission of the virus
5. The fin"ing of large6 multinucleate"6 clumps of cells in the bronchial secretions of a %
year ol" girl (ith acute bronchopneumonia suggests that this infection is cause" by
a. 0or"etella pertusis
b. Epstein/0arr virus
c. Mycoplasma hominis
". a rhinovirus
e. respiratory syncytial virus
7. !ll of the follo(ing picornaviruses are resistant to the aci"ity of the stomach e$cept8
a. Co$sac4ievirus !
b. Co$sac4ievirus 0
c. Echo virus
". &oliovirus
e. #hinovirus
9. ! "ivorce" mother of four tests positive for 1)/1 1nfection "uring investigation of a
febrile illness (ith "isseminate" lympha"enopathy. ! secon" en'yme immunoassay *E1!+ is
performe"6 an" the results are the same. The (oman "enies intravenous "rug use. She has
"ate" several men since her "ivorce an" can not be positive about their se$ual habits or use
of intravenous "rugs. What is the appropriate ne$t step in the management of this patient?
a. Treatment (ith 'i"ovu"ine *a'i"othymi"ine6 !:T+
b. !ll the patients close contacts (houl" be teste" for 1) antibo"ies
c. The public health authorities shoul" be notifie"
". ! (estern blot *immunoblot+ test shoul" be or"ere"
e. The patient shoul" be reassure" an" tol" that her "isease is probably unrelate" to !1.S.
;. 1n a chronic carrier of hepatitis 0 virus *0)+6 (hich positive test is most in"icative of
high infectivity?
a. epatitis 0 Surface !ntigen *bs!g+
b. epatitis 0 Core !ntigen *bc!g+
c. epatitis 0 e !ntigen *be!g+
". !nti/0s!g
e. !nti/0e!g
<. ! retrovirus is foun" in a high proportion of laboratory animals of a given species.
Most viremic animals are asymptomatic6 but others "evelop a fatal (asting syn"rome6 an" a
fe( "evelop leu4emia an" other tumors after long perio"s of latency. The virus in =uestion
most li4ely lac4s (hich one of the follo(ing genes?
a. gag
b. pol
c. env
". onc
1>. ! se$ually active %% year ol" college stu"ent presents to the local clinic (ith a
locali'e" vesicular eruption on the shaft of his penis. ! scraping of the base of one of the
vesicles is positive for T'anc4 cells. The patient mentions that he ha" a similar eruption in
the same area % months earlier. The reappearance of this eruption may be e$plaine" by8
a. Cell me"iate" immunity *CM1+ "eficiency in the patient
b. ! prolonge" perio" of viremia follo(ing the initial infection
c. ! secon" infection (ith a similar virus (ith a "ifferent serotype
". failure of the patient to comply (ith therapy prescribe" at the initial episo"e
e. reactivation of a latent infection
!ns(er ?eys
)irology8
1. b %. c -. a 2. c 5. " 7. b 9. a ;. c <. b 1>. " 11. c
1%. b 1-. e 12. c 15. " 17. a 19. " 1;. "