CALIFORNIA STATE UNIVERSITY, LOS ANGELES

COLLEGE OF ENGINEERING AND TECHNOLOGY

DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
EE 485 Introduction to Biomedical Devices
Fall 2014
Time and location T & Th 11:40 13:20, E&T C255-E
Instructor Deborah Won
Office location E&T A306
E-mail dwon@calstatela.edu
Course webpage
Office hours THU 13:30 15:00, FRI 08:30 09:00, FRI 11:30-12:30*
* If you are unable to come to these office hours, please e-mail me to make an appointment.
Course description
In this introduction to biomedical devices, students will explore the use of electronic circuit design in medical
instrumentation and gain basic skills and knowledge used in the biomedical device industry and research.
Topics include electronic device design of neural prostheses and signal conditioning circuitry for
bioelectrical signal acquisition and career options for biomedical engineers.
Co-requisites
EE 204 Circuit Analysis
Course objectives
By the end of this course, the student should
be able to describe a broad range of applications of electronics in biomedical instrumentation
explain the basic operation and design principles of certain major medical technologies (e.g., pacemaker,
EEG, retinal and cochlear prostheses)
be aware of various biomedical device companies and their major product lines
know fundamental issues in biomedical device design
have the capability to design solutions to common biomedical instrumentation problems (in biomedical
signal acquisition and stimulation)
have a general concept of translating technology to industry and the market
Topics covered include:
Sensors, transducers
Bioelectric potentials
Noise reduction
Amplifier circuits
Data sampling and transmission
Packaging
Biomedical applications:
EKG, EEG
cardiac pacing
cochlear implant
retinal prosthesis
NMES
CALIFORNIA STATE UNIVERSITY, LOS ANGELES
COLLEGE OF ENGINEERING AND TECHNOLOGY
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
DBS
medical imaging
Careers in biomedical device industry
Textbooks
Required: Medical Device Technologies, by Gail D. Baura (ISBN: 978-0-12-374976-5)
Recommended: Medical Instrumentation: Application and Design, by John G. Webster, 4
th
ed.
Supplementary material sets (SMS) will be supplied during the course:
1. SMS-MEMS: MEMS
2. SMS-EEG: EEG and BMIs
3. SMS-OA: OpAmps
4. SMS-SC: Signal conditioning circuits
5. SMS-DBS: Deep brain stimulation
6. SMS-NMES: Neuromuscular electrical stimulation
7. SMS-CI: Cochlear implant
8. SMS-RP: Retinal prosthesis

Course outline
Topic Reading Related Assignment
Introduction to biomedical devices Baura pp. 3-5; 33-34
Optional: Webster 1.1 1.5, 1.10
Problem Set 1
Introduction to prosthetic devices Baura pp. 389-392 + 433 444 +
322 326 + Optional: Webster
13.1 13.4
Problem Set 1
Sensors (mechanical + MEMS) Baura pp. 11-21
Optional: Webster 2.0 2.9;
Webster 13.8; SMS-MEMS
Problem Set 2
Bioelectric potentials and applications in
brain-machine interfaces
Baura pp. 40-41; 276-279.
Optional: Webster 4.1 - 4.2; 5.1 -
5.3 through p. 199
Problem Set 2
Electrode interface and nervous system
recordings
Baura pp. 42-47; 280-286; 289-
290. Optional: Webster 5.4 -
5.11, 4.4-4.5
Problem Set 3
Electroencephalogram and brain-machine
interfaces
Baura pp. 279-292; SMS-EEG.
Optional: Webster 4.8; 6.6
Problem Set 3
Review of op-amps; noise sources Data sheets (SMS-OA). Optional:
Webster 1.6 - 1.9
Problem Set 4
Signal conditioning SMS-SC; Webster 3.1 3.14 Problem Set 4
Amplifier circuits for signal conditioning SMS-SC Problem Set 4
CALIFORNIA STATE UNIVERSITY, LOS ANGELES
COLLEGE OF ENGINEERING AND TECHNOLOGY
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Electrocardiogram Baura p. 42-50; 52-56.Optional:
Webster 4.6; 6.1 - 6.5, 6.9
ECG lab
Cardiac pacemaker Baura pp. 60-65; 69-79.
Optional: Webster 13.0-13.1
through p. 599; 13.2-13.3
Project
Deep brain stimulation Baura pp. 298-311. SMS-DBS Project
Biomedical device design flow Project
Neuromuscular electrical stimulation +
EMG
Baura pp. 336-442; 345-352.
SMS-NMES. Optional: Webster
p. 602
Project, Reflex circuit
lab
Cochlear implant Baura pp. 316-332. SMS-CI Project
Retinal prosthesis Baura pp. 358-360; SMS-RP.
Optional: Webster p. 605
Project
Artificial pancreas Baura pp. 424-448 Project
Grading policy
10% Problem sets
30% Exam 1
30% Exam 2
30% Research paper
Homework is to be turned in by the start of class on the day it is due. Late homework will not be
accepted. Solutions will be posted online by 1 week after the due date (from the EE 485 Moodle page).
Grading scale
88 <= A <= 100
75 <= B < 88
62 <= C < 75
47 <= D < 63
F < 47
Academic Honesty
By taking this class, you agree to abide by the academic honesty policies described on the webpage:
http://www.calstatela.edu/usu/csi/StudentRights15.html. The University in its quest for truth and
knowledge embraces honesty and integrity. These fundamental values must not be compromised. The
trust and respect among professors, students and the society need to be vigilantly protected. Cheating
and plagiarism can be neither justified nor condoned as this would destroy the ideals and purposes of
higher education. Students enter the University to gain the knowledge and tools necessary for
participation in society. Academic integrity is one foundation for a society based on trust and honesty.
Therefore, the University takes seriously its responsibility for academic honesty.