Académique Documents
Professionnel Documents
Culture Documents
14.12.07
http://www.oie.int/downld/imprimeur/pdfs%20review
24-3/Dhand879-886.pdf
Year; 2005
Out of 18644 animals of 57 villages
973 Buffalo serum tested using ELISA
Overall incidences 12 %
Ranged from 0 to 24%
3 times higher incidences animals having the abortion history
Leptosprosis (zoonotic)
Economic loss
Infertility
Decrease milk
Occasionally death
Cause
Parasitic spirochetes genus Leptospira &
serovars
L. hardjo cattle
L. pomona pig and rodents
Transmission
Via
Infected urine
Post-abortive uterine discharge
Infected placenta
Sexual contact
Pathogenesis
Leptsira enters through m.membrane or water
softened skin
Incubation 4-10 days
________________ last for 7 days
Pyrexia
Excretion of lepto in milk
Clinical signs
Acute
in young
Pyrexia, anorexia, hemolytic anemia and jaundice
Lactating cow
Sever drop in milk production
Pink or red milk ?
Chronic
Fetal infection with 3rd trimester abortion 1-6
wks later or stillbirth
Control
Limit the contact of animal with contaminated
areas
Closed vaccination
Chlamydial infections
Epizootic bovine abortion
Mycobacterium
Salmonella
Fungal
Unknown bovine abortions
Sample collection:
Consult your veterinarian immediately. Collect all samples separately into clean containers
such as unused rectal sleeves, heavy garbage bags or sterile containers. Refrigerate
samples immediately and submit to diagnostic lab as soon as possible. Provide the
laboratory with the relevant history, clinical signs and diseases suspected.
____ aborted fetus
____ placenta &/or amniotic sac
____ amniotic fluids
____ feed samples (if mycotoxicosis is suspected - take a large, representative sample)
Paired blood samples provide the most useful diagnostic information. A (minimum) fourfold rise in the antibody titre to a specific disease agent in the second sample strongly
suggests that the animal was recently infected. Titres are commonly run for BVD / IBR /
Lepto / BRSV... Collect the blood samples in a tube that allows blood to clot (eg. a "red top
Vacutainer") and have your veterinarian freeze the first sample until the second is
collected.
____ acute blood sample - taken as soon as possible after abortion is observed
____ convalescent blood sample - collected 2 - 4 weeks after acute sample