BioS 220 Mendelian and

Molecular Genetics
Lecture 1. Cells and Genes
Chapter 1
Overview of genetics and the course
Syllabus
Some housekeeping details

Why Genetics?

Scuba Rice : a case study

Fig. 1 Swarna (left) and Swarna-Sub1 (right) in a farmer's field

after 10 days of complete submergence with turbid water in
Uttar Pradesh, India. The photo was taken 27 days after the
water receded.

http://www.youtube.com/watch?v=apWCqcury90
The contribution of submergence-tolerant (Sub1) rice varieties to food
security in flood-prone rainfed lowland areas in Asia.
Ismail, Singh,
Singh, Dar, Mackill. 2013. Field Crops Research 152: 83 - 93

http://www.youtube.com/watch?feature=player_detailpage&v=shCHe1eAQoQ

Fig. 3 Yield of Samba Mahsuri and Samba Mahsuri-Sub1 after variable durations of
submergence in farmers fields. Data are from farmers in Uttar Pradesh, India, during the
wet season of 2011 ( n = 59).

Website for s\detailed stories of SUB1

and accelerated genetic improvement of crops.
http://www.authorstream.com/Presentation/aSGuest10
8849-1136509-marker-assisted-breeding/

0.001 mm

10 mm

Genetics asks:
Why are children like their parents?

0.001 mm

10 mm

Genetics asks:
Why are children like their parents?
Why are children different from their parents?

Tools of Genetic Analysis

Mutation
Crosses
Biochemistry
Cytology
DNA Structure
DNA
manipulation

Gregor Mednel at
Augustinian Abbey, Brno, Bohemia

GENETICS
I. Rules of inheritance (of genes)
a. are inferred from PATTERNS of gene
transmission from one generation to the next

Mendel, 1865

b. are used, once known,

to study nature and function of genes
to deduce individual genes properties
to predict offspring types
II. Biochemical study of gene function gives more
precise understanding of gene action.

Avery, 1944

Genetics: careful examination of CROSSES

Parent 1
genes
traits

n offspring:
Mating

Parent 2
genes
traits

1: genes / traits
2: genes / traits
3: genes / traits
4: genes / traits
5: genes / traits
...
n: genes / traits

DNA ----> RNA ----> PROTEIN

New fig 1-9 here!

RNA ----> PROTEIN

BioS 220 -

Course Plan

Grading
Final Exam
Hour Exam I
Hour Exam II
Quizzes
i-clicker credit
Homework sets
Problem set I
Problem set II
Total

150
100
100
90
50
30
20
20
560

Sources of Information
Text: Griffiths, Genetic Analysis 10th Ed
>>> do many problems ! <<<
Lectures
(notes posted before class)
Discussions (Fridays, starting week 2)
Office Hours
Morrison: Weds 4-5 in SCE cafeteria
TAs:
SLC Darwin, starting week 2
(Lab) (Other texts ad lib)

Note:
in week 1 (only),
we have three lectures
and no Discussion sections

Where are TA Office Hours held?

A LC-A1
B SCE Cafeteria
C BSB Cafeteria
D SLC Darwin
E BSB Cafeteria

Where are my Wednesday Office Office Hours held?

A LC-A1
B SCE Cafeteria
C BSB Cafeteria
D
SLC Darwin
E
BSB Cafeteria

Where does class meet this Friday?

A
B
C
D
E

No lecture, only disc. Sections

LC-A1
Giordanos
BSB Cafeteria
SES 250

What should you always bring to class?

A
B
C
D
E

Hat and Gloves

Textbook
Lecture notes
i>Clicker remote
C and D

Have you completed General Chemistry

(112/114 or 116/118)?
A Completed
B This semester
C Not yet

Have you completed Organic Chemistry (232/234)?

A Completed
B This semester
C Not yet

Have you completed Introductory Physics?

A Completed
B This semester
C Not yet

Have you completed Bios 222 Cell Biology?

A Completed
B This semester
C Not yet

Where are test answer keys posted?

A
B
C
D
E

LC-A1
SEL 3289
SLE
MBRB
Addams Hall

How many of your classes have used i>Clickers?

A
B
C
D
E

None
1
2 or 3
4 or 5
More than 5

BioS 220
An i>clicker remote is
required for this course.
You can purchase it
through the bookstore.

How will we
use the clicker?

I pose questions on the screen during

lecture.

You answer using your i>clicker remote.

Class results are tallied.

I display a graph with the class results

on the screen.

We discuss the questions and answers.

You get 1 point for participating and 4

for answering correctly)!

How do you vote?

Turn on the clicker by
pressing the bottom
On/Off button.
A blue Power light will
appear at the top of the
remote.

How do you vote?

When I ask a question in
class (and start the
timer), select A, B, C, D,
or E as your vote.

How do you know your

vote was received?
Check your Vote Status Light:
Green light = your vote was sent
AND received.
Red flashing light = you need to vote
again.
Not sure you saw the light? Just
vote again.
Want to change your vote? You can
vote again as long as the timer is still
going.

Registering your i>clicker

You can earn points for your i>clicker
responses [for participation and/or
answering questions correctly].
Until you register your i>clicker, your
responses are tied to your clicker remote ID
(located on the back of your clicker), rather
than to you.
When you do register, your previously
recorded voting responses will be assigned
to you.

Registering
your i>clicker unit
1.
2.
3.
4.

Go to BlackBoard.
Go to Bio 220.
Under Tools:
Enter your iClicker
serial number.

Other tips
If you bought a used clicker, replace the batteries.
Register your clicker by January 21.
Before using a new clicker for the first time, pull the
plastic tab out of the battery compartment.
Bring your clicker to class every day!
Make sure your remote is on when voting!
Check out www.iclicker.com for FAQs.
Contact support@iclicker.com for help.