SYLLABUS HUMAN GENETICS, BIO 1318, Fall, 2005, MC 2.410 (TR 9:30-10:45) Textbook: Essential Genetics: A Genomics Perspective, 4th ed.

, by Hartl & Lewis, 2006* Instructor: Dr. Lee Bulla (FN3.112), 972.883.4226, lee.bulla@utdallas.edu Office hours: Tue & Thur 11:00-12:00 Teaching Assistant: Dr. A. Dixit, and044000@utdallas.edu Genetics is the study of biologically inherited traits. Each species of living organisms is united by a common set of inherited traits, observable characteristics that set it apart from all other species of organisms. In this course, we will address three major questions. What is the chemical nature of the genetic material? How is the genetic material transmitted? And what does it do? These questions will be examined and discussed from a genomics perspective. Five exams will be given throughout the semester. The final grade will be based on the average of four of the five exams. No make-up exam will be given for absence from an exam other than for official university business or illness (both require either a written university authorization or a physician’s statement). All hand-held electronic devices, including cell phones, must be stored away during exams. Lecture outlines will be posted on the course web site. It is fully expected that students will attend and participate in the lectures and discussions. LECTURE 1 2 3 4 5 6 7 8 9 10 11 12 13 DATE 18 Aug 23 Aug 25 Aug 30 Aug 1 Sep 6 Sep 8 Sep 13 Sep 15 Sep 20 Sep 22 Sep 27 Sep 29 Sep 4 Oct 6 Oct 11 Oct 13 Oct 18 Oct 20 Oct 25 Oct 27 Oct 1 Nov 3 Nov 8 Nov 10 Nov 15 Nov 17 Nov 22 Nov LECTURE SCHEDULE TOPIC The Genetic Code of Genes and Genomes Transmission Genetics: Heritage from Mendel - 1 Transmission Genetics: Heritage from Mendel - 2 The Chromosomal Basis of Heredity - 1 The Chromosomal Basis of Heredity - 2 EXAM 1 Human Chromosomes and Chromosome Behavior DNA Structure, Replication and Manipulation - 1 DNA Structure, Replication and Manipulation - 2 DNA Structure, Replication and Manipulation - 3 EXAM 2 The Molecular Genetics of Gene Expression - 1 The Molecular Genetics of Gene Expression - 2 Molecular Mechanisms of Gene Regulation -1 Molecular Mechanisms of Gene Regulation - 2 Review for Exam 3 EXAM 3 Genomics, Proteomics and Genetic Engineering - 2 Genomics, Proteomics and Genetic Engineering - 2 The Genetic Control of Development - 1 The Genetic Control of Development - 2 Molecular Mechanisms of Mutation and DNA Repair EXAM 4 Molecular Genetics of the Cell Cycle and Cancer -1 Molecular Genetics of the Cell Cycle and Cancer - 2 Molecular Evolution and Population Genetics - 1 Molecular Evolution and Population Genetics -2 The Genetic Basis of Complex Inheritance EXAM 5 CHAPTER 1 2 2 3 3 1, 2, & 3 5 6 6 6 5&6 8 8 9 9 8&9 10 10 11 11 12 10, 11 & 12 13 13 14 14 15 13, 14 & 15

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