THERAPEUTIC FLOW SHEET

1. Citicoline 1 gm/tab 1 tab OD

MOA: Citicoline seems to increase a brain chemical called phosphatidylcholine. This brain chemical is important
for brain function. Citicoline might also decrease brain tissue damage when the brain is injured.
Indications: Citicoline is used for Alzheimer's disease and other types of dementia, head trauma,
cerebrovascular disease such as stroke, age-related memory loss, Parkinson's disease, attention deficithyperactive disorder (ADHD), and glaucoma.
2. Ciprofloxacin (ciprobay) 500mg/tab 1tab BID
MOA: The bactericidal action of Ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA
gyrase) and topoisomerase IV (both Type II topoisomerases), which are required for bacterial DNA replication,
transcription, repair, and recombination.
Indications: Urinary Tract Infections, Acute Uncomplicated Cystitis in Females, Chronic Bacterial Prostatitis,
Lower Respiratory Tract Infections, Acute Sinusitis, Skin and Skin Structure Infections , Bone and Joint Infections,
Complicated Intra-Abdominal Infections (used in combination with metronidazole), Infectious Diarrhea.
3. Valsartan + amlodipine (exforge) to 160 mg/10mg, 1 tab OD
MOA:
Amlodipine = Inhibits movement of calcium ions across cell membranes in systemic and coronary vascular
smooth muscle.
Valsartan = Antagonizes the effect of angiotensin II (vasoconstriction and aldosterone secretion) by blocking the
angiotensin II receptor in vascular smooth muscle and the adrenal gland, producing decreased BP.
Indications: Treating high blood pressure. It may be used alone or with other medicines. It may also be used for
other conditions as determined by your doctor.Amlodipine/valsartan is a calcium channel blocker and
angiotensin II receptor blocker combination. It works by relaxing the blood vessels.
4. Metoprolol 50mg/tab 1 tab BID
MOA: Metoprolol tartrate is a beta1-selective (cardioselective) adrenergic receptor blocker. This preferential
effect is not absolute, however, and at higher plasma concentrations, Metoprolol tartrate also inhibits beta2adrenoreceptors, chiefly located in the bronchial and vascular musculature.
Indications: Hypertension, Angina Pectoris, Myocardial Infarction
5. Metformin 500mg/tab 1 tab OD
MOA: Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2
diabetes, lowering both basal and postprandial plasma glucose. Its pharmacologic mechanisms of action are
different from other classes of oral antihyperglycemic agents. Metformin decreases hepatic glucose production,
decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose
uptake and utilization.
Indications: are indicated as an adjunct to diet and exercise to improve glycemic control in adults and children
with type 2 diabetes mellitus.

6. Aspirin 80mg 1tab 1tab OD

MOA: Low doses (typically 75 to 81 mg/day) are sufficient to irreversibly acetylate serine 530 of cyclooxygenase
(COX)-1. This effect inhibits platelet generation of thromboxane A2, resulting in an antithrombotic effect.
Intermediate doses (650 mg to 4 g/day) inhibit COX-1 and COX-2, blocking prostaglandin (PG) production, and
have analgesic and antipyretic effects.
Indications: Aspirin is used to treat pain, and reduce fever or inflammation. Aspirin is sometimes used to treat or
prevent heart attacks, strokes, and chest pain (angina). Aspirin should be used for cardiovascular conditions only
under the supervision of a doctor.
7. Omeprazole 20mg/ cap 1 cap OD pre Break fast
MOA: Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress
gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the
gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric
mucosa, Omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of
acid production.
Indications: omeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other
conditions caused by excess stomach acid. It is not for immediate relief of heartburn symptoms.Omeprazole is
also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Omeprazole may also be given together with antibiotics to treat gastric ulcer caused by infection with
helicobacter pylori (H. pylori).
8. Atorvastatin (Lipitor) 40mg/tab 1 tab OD at HS
MOA: Atorvastatin calcium is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme
that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of sterols, including
cholesterol.
Indications: Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other
heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.Atorvastatin is
used in adults and children who are at least 10 years old.Atorvastatin may also be used for purposes not listed in
this medication guide.
9. Allopurinol (allurase) 300mg/tab 1tab OD
MOA: Allopurinol is a structural analogue of the natural purine base, hypoxanthine. It is an inhibitor of xanthine
oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid, the
end product of purine metabolism in man.
Indications: Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who
are receiving cancer treatment. Allopurinol may also be used for purposes not listed in this medication guide