First 100 Mcqs and their answers

? Which of the following is not an indication for Tranexamic Acid -1

a- Treatment of heamorrhage associated with excessive fibrinolysis
b- An antidote for Streptokinase overdose
c- Prophylaxis of hereditary angioedma
d- Prevent heammorhage due to Heparin overdose

i2- Which of the following drugs does not cause insomnia ?i

a- MAOIs
b- Caffeine
c- Beta blockers
d- Barbiturates

?i3- Which of the following is a lipid lowering drugs

a- Aprotinin
b- Tranexamic acid
c- Lansoprazole
d- Acipimox

i4- Which of the following H2 receptors antagonist has the highest affinity for
? cytochrome p450
a- Nizatidine
b- Ranitidine
c- Cimetidine
d- Famotidine

i5- Which of the following side effects will be caused by antacids containing
NAHCO3?i
a- Belching
b- Constipation
c- Diarrhea
d- Blurred vision

i6- Which of the following is a dopamine antagonist?i

a- Granisetron
b- Domperidone
c- Cisapride
d- Loperamide

i7- Which of the following drugs is a systemic amoebicide?i

a- Diloxamide furoate
b- Pyrimethamine
c- Emetin
d- Sodium Stibogluconate

i8- Which of the following drugs is the drug may cause discolouration of nail
beds and mucus membranes?i
a- Tetracycline
b- Chloroquine

c- Doxycycline
d- Rifampicin

i9- Which of following drugs is the drug of choice for the treatment of all forms
of Schistosomiasis?i
a- Praziquantel
b- Mebendazole
c- Niclosamide
d- Thiabendazole

i10- Which of the following drugs can be used for the treatment of influenza A
infection ?i
a- Zidovudine(AZT)i
b- Amantadine
c- Ribavarin
d- Vidarabine

Which of the following drugs is used in the treatment of Leishmaniasis?i -11

a- Pyrimethamine
b- Diloxamide
c- Sodium Stibogluconate
d- Emetin

i12- Which one of the following statements about tetracycline is not correct?i
a- It is useful for the treatment of resistant strains
b- It is contraindicated in pregnancy
c- It is safe in infections caused by Chlamydia
d- It can lead to discolouration of teeth if given to children

i13- Which of the following drug will antagonize Methotrexate?i

a- Thiamine
b- Folic acid
c- Biotin
d- Cyanocobalamin

i14- lodine is found in all of the following except:i

a- Cod liver oil
b- Sea food
c- Kelp
d- Iodized salt

i15- Match the statements (1- 4) to the trace elements (A-D) listed below.each
answer may be used more than once
a- Zinc b- Copper c- Chromium d- Selenium
i1.
i2.
i3.
i4.

Formation of red and white blood cells

Protects cells against damage during cellular m etabolism
Promotes wound healing and normal growth
Helps maintain normal glucose m etabolism

i16- Match the drug characteristics (1- 4) with the drug listed below (a-d). each
answer may be used more than once
a- Auranofin
b- Pencillamine

c- Aspirin
d- Corticosteroids

i1- Platelet function effect

i2- Oral form of gold
i3- Given on an empty stomach
i4- May be given intra articularly

i17- for each side effect (1- 4) list the most likely cause (a-d). each answer may be
used more than onces
a- Sodium Bicarbonate
b- Aluminium Hydroxide
c- Amitriptyline
d- Magnesium Hydroxide
i1i2i3i4-

May cause diarrhea

Should not be used by patient of heart failure
May cause dry mouth
Can be incorporated with an antacids mixture to control diarhoea

i18- Pyridoxine requirements may increase during administration of all the

following except:i
a- Isoniazid
b- Cycloserine
c- Oral contraceptives
d- Levodopa

i19- All of the following preparations contain alcohol except:i

a- Syrup simplex
b- Aromatic ammonia spirit USP
c- Terpin hydrate elixir USP
d- Belladona tincture B.P

i20- Wich of the following solutions is used as an astringent?i

a- Strong iodine soluotin USP
b- Aluminium acetate topical solution USP
c- Acetic acid NF
d- Benzalkonium chloride solution NF

anextrapyramidal adverse effects is caused by the blocking of:i -21

a- Serotonin receptors in the brain
b- Acetylcholine receptors in the brain
c- Dopamine receptors in the brain
d- Dopamine receptors outside the brain

i22-A rare side effect of some anticonvulsants is Stevens-Johnson

syndrome.this is a severe:i
a- Skin reaction
b- Bone marrow toxicity
c- Renal failure
d- CNS suppression

i23-If a women,receiving carbamazepine becomes pregnant,it is

important that she receives daily supplements of :i
a- Vit A

b- Vit B6
c- Folic acid
d- Riboflavin

i 24-Which of the following are side effects of phenytoin treatment?i

a- Acne
b- Hirsuitism
c- Gingival hyperplasia
d- a,b,and c

i25-Which drug is considered as Alpha-1- Adrenergic blocker : i

a- Hydralazine
b- Minoxidil
c- Prazosin
d- Guanethidine

i26-Nitroglycerin-all the following are true except :i

a- Can be dispensed in hospital pack of 500 and 1000 tabs
b- Containers must be made of glass and be covered with a tight-fitting ----l
c- Close tightly after use
d- Tablets must be stored at controlled R.T
e- Tablets not to be refrigerated

i27-The most important adverse reaction to terbutaline is :i

a- Tachycardia
b- CNS stimulation
c- Fine muscle tremor
d- Gastric irritation
e- All of the above

i28-Which of the following is true about Penicillin V ?i

a- It is inactivated by gastric acid
b- It is acid stable
c- It is more active than Benzylpencillin
d- It is absorbed better after foods

i29- Which of the following is a quinolone antibiotic ?i

a- Clindamycin
b- Chlortetracycline
c- Ciprofloxacin
d- Clarithromycin

i30-Tuberculosis is caused by a :i
a- Mycoplasma
b- Mycobacterium
c- Micrococcus
d- Microbacter

pertussis is another name for :i-31

a- Cough
b- Diphtheria
c- Whooping cough
d- Scarlet fever

i32-in the treatment of pulmonary tuberculosis,antibiotic treatment must

be continued for at least :i

a- 6 months
b- 4 months
c- 2 months
d- 1 month

i33-all of the following are prodrugs except :i

a- Sulindac
b- Diazepam
c- Enalapril
d- Sulfasalazine

i34-which route of drug administration is likely to subject a drug to first

pass effect ?i
a- Intravenous
b- Inhalation
c- Oral
d- Sublingual

i35-which of the following statements is/are correct?i

a- Ketamine is used in the treatment of migraine
b- Acute systemic anaphylaxis should be treated immediately by IV injection of
adrenaline
c- Sulphonylureas are oral anticoagulants
d- None of the above

i36-verapamil exerts its effects through which of the following actions?i

a- Preventing entry of calcium channels through slow channels
b- Increasing sodium entry
c- Antagonizing the opening of the fast sodium channel
d- None of the above

i37-cardiac glycoside may be useful in treating all of the following

except :i
a- Atrial flutter
b- Congestive heart failure
c- Ventricular tachycardia
d- Atrial fibrillation

i38-streptokinase is indicated for the treatment of :i

a- Impaired fat absorption
b- Pulmonary emboli
c- Tuberculosis
d- Psoriasis

i39-tretinoin is used therapeutically :i

a- As a urinary acidifier
b- As an antifungal agent
c- In the treatment of tuberculosis
d- In the treatment of acne

i40-a calcium channel blocker that is used parenterally for cardiac

arrythmias is :i
a- Verapamil hcl

b- Nefedipine
c- Captopril
d- Minoxidil

Wich of the following has not been used for the treatment of -41
Parkinsonism ?i
a- Cogentin
b- Artane
c- Tofranil
d- Kemadrin

i42-The drug that is most likely to induce bronchospasm is :i

a- Pindolol
b- Pentoxyfylline
c- Omeprazole
d- Lisinopril

i43-The anti-inflammatory effect of aspirin is due to :i

a- An anticoagulant effect
b- Inhibition of the synthesis of prostaglandins
c- An antigen-antibody reaction
d- All of the above

i44-The most useful drug in the treatment of diabetes insipidus is :i

a- Glibenclamide
b- Insulin
c- Metoclopramide
d- Desmopressin acetate

i45-The tricyclic antidepressant Iimipramine (Tofranil) has been

approved by FDA for use in :i
a- Parkinson's disease
b- Hypertension
c- Eneuresis
d- Peptic ulcer
e- None of the above

i46-Regular use of sublingual doses of Nitroglycerin is likely to result

in :i
a- Hepatotoxicity
b- Nephrotoxicity
c- Peptic ulcer
d- Tolerance

i47-All of the following are beta blockers except :i

a- Metoprolol (Lopressor)i
b- Nadolol (Corgard)i
c- Enalapril (Renitec)i
d- Propranolol (Inderal)i

i48-Bisacodyl frequently can cause :i

a- Abdominal cramps

b- Constipation
c- Skin rashes
d- Dizziness

i49-An example of a pure opioid antagonist :i

a- Naloxone hcl (Narcan)i
b- Pentazocine (Sosegon)i
c- Nalbuphine(Nubain)i
d- Morphine

i50-Carbamazepine (tegretol) is used for treatment of :i

a- Eneuresis
b- Trigeminal neuralgia
c- Attention of defict disorder
d- Psoriasis

Buspirone (Buspar) is classified pharmacologically as :i-51

a- Antidepressant
b- Anxiolytic agent
c- Narcotic analgesic
d- Hypnotic

i52-Dilitiazem is used primarily for its ability to produce :i

a- Cough depreaaion
b- Analgesia
c- Calcium channel blockade
d- Emesis

i53-Carbocysteine is an agent used clinically as :i

a- Laxative
b- Cough suppressant
c- Diagnostic agent
d- Mucolytic

i54-The following drugs may be given by sublingual route except :i

a- Digoxin
b- Nifedipine
c- Nitroglycerin
d- Isoprenaline

i55-Match the following antibiotics to the best description given below

(a-d)i
a- Betalactam antibiotic active against pseudomonas
b- Pencillinase resistant betalactam
c- Contraindicated in children
d- Inhibits renal metabolism
i1- Piperacillin
i2- Tetracycline
i3- Flucloxacillin
i4- Cilastin

i56-Disinfectants are expected to destroy or inhibit the growth of

microbes which are in :i
a- The vegetative stage

b- The sporing stage

c- Both a and b
d- None of the above

i57-Which of the following is not a storage area for iron:i

a- Reticuloendothelial system
b- Kidney
c- Hepatocytes
d- Muscle

i58-Which of the following is a sulphonylurea antidiabetic drugs?i

a- Chlorpropamide
b- Bum etanide
c- Acetazolamide
d- Frusemide

i59-One drop has a volume of :i

a- 0.5 ml
b- 0.1 ml
c- 0.15 ml
d- Variable, depending on the liquid and the dropper

: i60-Ketorolac is used in eye preparations as a/an

a- Anti-inflammatory
b- Antihistamine
c- Astringent
d- Corticosteroid

i61-Which of the following drugs is a vasodilator?i

a- Methyldopa
b- Mexitilline
c- Prazocin
d- Propranolol

i62-Which of the following drugs is not associated with haemolytic

aneamia?i
a- Mefenamic acid
b- Methyldopa
c- Methadone
d- Methyl testosterone

i63-Which of the following Vitamins is essential in the formation of

Prothrombin?i
a- Vitamin A
b- Vitamin B complex
c- Vitamin E
d- Vitamin K

i64-Which of the following is not used as an antitussive ?i

a- Noscapine
b- Pethidine
c- Codeine
d- Diphenhydramine

i65-Which of the following Local Anaesthetics is useful for topical

administration only?i
a- Lidocaine

b- Bupivacaine
c- Benzocaine
d- Procaine

i66-The iron preparation given by the intravenous route is:i

a- Ferrous sulphate
b- Iron-dextran
c- Ferrous gluconate
d- Iron-sorbitol citric acid

i67-Carotenoids are precursors for which vitamin?i

a- Vitamine E
b- Vitamine D
c- Vitamine A
d- Vitamine K

i68-Which of the following is recommended for dyspepsia in pregnancy?

i
a- Gaviscon
b- Pylorid
c- De-nol
d- Zantac

i69-Which of the following drug interactions is not used therapeutically?

i
a- Epinephrine / Lidocaine
b- Probenicid / Penicillin
c- Pseudoephedrine / Salbutamol
d- Trimethoprim / Sulphamethoxazole

i70-The maximum daily dose of Glibenclamide is

a- 2.5 mg/day
b- 5 mg/day
c- 20 mg/day
d- 30 mg/day

i71-Which of the following is not used to treat psychosis?i

a- Aluoxetine
b- Haloperidol
c- Perphenazine
d- Resperidone

i72-A sympathomimetic often present in OTC appetite suppressant is:i

a- Ephedrine
b- Phenylephedrine
c- Phenylpropanolamine (PPA)i
d- Caffeine

i73-Opioids have the following uses except:i

a- Anti tussive
b- Anti-inflammatory
c- Analgesics
d- Pre anaestetics

i74-Levocabastine is a/an:i
a- Antihistamine
b- Anti microbial
c- Anti inflammatory
d- Corticosteroid

i75-Which of the following is not used as aprophylaxis for migraine?i

a- Pizotifin
b- Metoprolol
c- Prazocin
d- Propranolol

i76-The most common side effect of sublingual glyceryl trinitrate is:i

a- Nausea
b- Throbbing headache
c- Hypertension
d- Skin rash

i77-All of the following are common iodine deficiency symptoms

except:i
a- Goitre
b- Intellectual disability
c- Growth retardation
d- Decreased early and late pregnancy miscarriage

i78-Which of the following insulins has the shortest duration of action?i

a- Isophane insulin
b- Soluble insulin
c- Insulin zinc suspension
d- Protamine zinc insulin

i79-Vasopressin (ADH) is used therapeutically for:i

a- Treatment of polyuria caused by hypercalceamia
b- Treatment of pituitary diabetes insipidus
c- Decrease chest pain in refractory unstable angina
d- Increasing uterine contractivity

i80-oral sympathomimetic decongestants should be avoided in patients

who have:i
a- Asthma
b- Cough
c- Hypertension
d- Throat infections

Percentage of total body iodine in thyroid glands is :i-81

a- 50%
b- 75%
c- 90%
d- 95%

i82-Daily saliva secretion is :i

a- 1 litres
b- 1.5 litres
c- 1.8 litres
d- 2 litres

i83-Normal serum bilirubin is :i

a- 0.5 - 1 mg %i
b- 1 - 3 mg %i
c- 3 - 4 mg %i
d- 4 - 5.5 mg %i

i84-Ovary secretes :i
a- FSH and LH only
b- Oestrogen and Progestrogen only
c- Oestrogen, Progestrogen and Androgen
d- All of these

i85- The absence of anti-A and anti-RH agglutinin plasma means that the
subject is :i
a- A+ve or AB+ve
b- A-ve or AB-ve
c- B+ve or AB+ve
d- Type O

i86-The most important buffer in extracellular fluids is:i

a- Acetate
b- Bicarbonate
c- Phosphate
d- Protein

i87- Reticulocytosis indicate :i

a- Increased RBC formation
b- Decreased WBC formation
c- Decreased RBC formation
d- Increased WBC formation

i88-Ketosteroids in urine include :i

a- Adrenal and testicular function
b- Pituitary function
c- Hypothalamic function
d- Pancreatic function

i89-Which blood can be safely given to a patient of blood group AB

positive?i
a- AB negative
b- A positive
c- B positive
d- O positive

i90- Function of gall bladder is :i

a- Increase alkalinity of bile
b- Increase concentration of bile
c- Increase intrabiliary presence
d- Increase phosphate level

Insulin causes :i-91

a- Increase glucose m etabolism
b- Increase gluconeogenesis
c- Increase lipolysis
d- Increase glycogenolysis

i92- Major pathway of excretion of Calcium is :i

a- Kidney
b- Gut
c- Kidney and Gut
d- None of the above

i93- The secretion of aldosterone is controlled by :i

a- Angiotensin
b- ACTH
c- Epinephrine
d- Insulin

i94- First relay station of pain is :i

a- spinal cord
b- Medulla
c-pons
d- thalamus

i95- Testosterone is secreted by :i

a- sertoli cells
b- leydig cells
c- germ cells
d- adrenal medulla

i96- Which neurotransmitter controls secretion of prolactin?i

a- Dopamine
b- Serotonin
c- Somatostatin
d- GABA

i97- Nucleus of a atom contains :i

a- Electrons
b- Only Protons
c- Electrons and Protons
d- Protons and Neutrons

i98- Which of the following is the fastest to be absorbed from the

stomach?i
a- Carbonhydrate
b- Proteins
c- Fats
d- Water

i99- Function of calcitonin is to :i

a- Decrease level of Calcium
b- Increase level of Calcium
c- Increase level of Mg
d- Increase level of Potassium

i100- The following are true of insulin except :i

a- Glycopeptide
b- Secreted by beta cells
c- Causes lipogenesis
d- Promotes glycogenesis

i1-----------------------D
i2-----------------------D
i3-----------------------D
i4-----------------------C
i5-----------------------A
i6-----------------------B
i7-----------------------A
i8-----------------------D
i9-----------------------A
i10----------------------B
---------------------------------------------------------------i11----------------------C
i12----------------------A
i13----------------------B
i14----------------------A
i15
i1------------------B
i2------------------D
i3------------------A
i4------------------C
i16
i1------------------C
i2------------------A
i3------------------B
i4------------------D
i17
i1------------------D
i2------------------A
i3------------------C
i4------------------B
i18-----------------D
i19-----------------A
i20-----------------B
----------------------------------------------------------------

i21-----------------------C
i22-----------------------A
i23-----------------------C

i24-----------------------D
i25-----------------------C
i26-----------------------A
i27-----------------------E
i28-----------------------B
i29-----------------------C
i30-----------------------B
----------------------------------------------------------------

i31-----------------------C
i32-----------------------A
i33-----------------------B
i34-----------------------C
i35-----------------------B
i36-----------------------A
i37-----------------------C
i38-----------------------B
i39-----------------------D
i40-----------------------A

----------------------------------------------------------------

i41-----------------------C
i42-----------------------A
i43-----------------------B
i44-----------------------D
i45-----------------------C
i46-----------------------D
i47-----------------------C
i48-----------------------A
i49-----------------------A
i50-----------------------B
----------------------------------------------------------------

i51-----------------------B
i52-----------------------C
i53-----------------------D
i54-----------------------A
i55
i1------------------A
i2------------------C
i3------------------B
i4------------------D
i5------------------C
i56-----------------------A
i57-----------------------B
i58-----------------------A
i59-----------------------D
i60-----------------------A
----------------------------------------------------------------

i61-----------------------C
i62-----------------------D
i63-----------------------D
i64-----------------------B
i65-----------------------C
i66-----------------------B
i67-----------------------C
i68-----------------------A
i69-----------------------C
i70-----------------------C
----------------------------------------------------------------

i71-----------------------A
i72-----------------------C
i73-----------------------B
i74-----------------------A
i75-----------------------B
i76-----------------------B
i77-----------------------D
i78-----------------------B

i79-----------------------B
i80-----------------------C
----------------------------------------------------------------

i81-----------------------C
i82-----------------------D
i83-----------------------A
i84-----------------------C
i85-----------------------A
i86-----------------------B
i87-----------------------A
i88-----------------------A
i89-----------------------A
i90-----------------------B
----------------------------------------------------------------

i91-----------------------A
i92-----------------------B
i93-----------------------A
i94-----------------------A
i95-----------------------B
i96-----------------------A
i97-----------------------D
i98-----------------------D
i99-----------------------A
i100----------------------A